inflammation

  1. haidut

    Blocking endotoxin (TLR4) may prevent death from viral infections (COVID-19/ARDS)

    Almost a decade ago I posted about a "rogue" study which had the audacity to suggest that most of so-called viral infections (including HIV) produce most of their most severe symptoms not through the virus or its direct effects, but through synergism with the bacterial endotoxin (LPS) that we...
  2. haidut

    Dietary PUFA (linoleic acid) causes inflammatory bowel disease (IBD)

    The rates of IBD have truly skyrocketed over the last 10-15 years, significantly surpassing the general increase seen in most chronic conditions, especially in people younger than 40. Over the last couple of years, I posted about studies showing artificial colors (e.g. Red 40), silicon dioxide...
  3. haidut

    Vitamin E reduces exercise-induced muscle damage

    Nothing much to add here and the article title is essentially identical to my post. I am mostly posting this as a possible "remedy" for the many people who engage in endurance exercise, usually with the (misguided) goal to lose weight. As the study says, the effects of vitamin E are most...
  4. haidut

    Media: Endotoxin (LPS) drives obesity/diabetes

    I did not think we will ever see such a headline in a major news outlet, but here is is. And in The Guardian of all places, which is a newspaper that rarely deviates from the official medical narrative on any condition, especially obesity and diabetes. The official narrative for those conditions...
  5. haidut

    Vitamin E may prevent, treat rheumatoid arthritis (RA) by restoring the gut barrier

    This is one of those studies where the most important finding is not directly stated, but implied. Namely, if healing the gut barrier, as the study says, may prevent/treat RA then the condition is most likely tied to the microbiome in our GI tract. More specifically, to the byproducts of the...
  6. haidut

    Endotoxin, cold, flue increase risk of dementia

    I am posting this study not so much because of the link between chronic low-grade inflammation and neurological conditions it demonstrates. That link is by now well-known even in mainstream medical circles. The main reason this study/article caught by eye is that the experiment mimicked the...
  7. haidut

    Vitamin D may ameliorate/resolve (allergic) asthma

    It looks like vitamin D may be the "vitamin" (actually, seco-steroid) analog of aspirin - i.e. there is hardly a condition where this humble "vitamin" has not demonstrated beneficial effects. The new study now adds asthma to the list of chronic, debilitating (and potentially lethal) conditions...
  8. haidut

    Aspirin may treat (idiopathic) pulmonary fibrosis (PF)

    I mentioned in several of my latest podcast appearances that Pfizer is running clinical trials with a serotonin antagonist to reverse/treat several lethal conditions, for which medicine claims there is no cure. Those conditions include heart fibrosis / heart failure, pulmonary hypertension...
  9. B

    Aspirin in the context of Endotoxin Tolerance

    Summary of studies: Endotoxin tolerance (ET) is a reduced responsiveness to a LPS challenge following a first encounter with endotoxin. Chronically, this may lead to local or systemic immunosuppression. Despite ongoing low-grade tissue irritation, only a blunted immune response is mounted. On...
  10. haidut

    Declining DHT in aging linked to cardiovascular disease (CVD)

    Yet another study demonstrating that the "villain of all males around the world" - the dastardly androgen dihydrotestosterone (DHT) - actually is, in all likelihood, beneficial for males, at least when it comes to their cardiovascular health. However, since CVD is one of the risk factors for...
  11. haidut

    Serum endotoxin level is a reliable biomarker of liver disease

    It looks like the interest in gut-derived pathogenic substances is steadily increasing in the medical field. After claiming for decades (and still doing so) that liver disease is either genetic in origin or driven mostly by sugar (especially fructose) consumption, now studies like the one below...
  12. haidut

    A ubiquitous dishwasher rinse agent may cause many serious diseases

    Another article demonstrating that a ubiquitous chemical, widely used in both industrial and household settings, has very toxic effects on the GI tract of humans and can directly cause a number of GI and neurological diseases, as well as cancer. While the study only looked at the so-called...
  13. P

    Doxycycline , intestinal health, hypertension

    Changes in Gut Microbiota Induced by Doxycycline Influence in Vascular Function and Development of Hypertension in DOCA-Salt Rats DOX decreased lactate-producing bacterial population and plasma lactate levels, improved gut barrier integrity, normalized endotoxemia, plasma noradrenaline levels...
  14. haidut

    Mitochondrial dysfunction is a major cause of cardiovascular disease (CVD)

    At a first glance, mitochondrial dysfunction (a "functional" problem) has little in common with the build-up of plaque on arterial walls (a "structural" problem). However, as my readers know quite well, structure and function cannot be separated and a functional pathology is perfectly capable...
  15. haidut

    Glycine may prevent/treat diabetic neuropathy

    A very interesting study, which adds more evidence in favor of the recent hypothesis that glycine (just as taurine) is in fact an essential amino acid. Namely, despite our ability to synthesize glycine, as needed, from the truly essential amino acids, its absence in the diet leads to pathologies...
  16. haidut

    Blocking PUFA metabolism may treat Amyotrophic Lateral Sclerosis (ALS)

    The disease ALS needs no introduction. It is perhaps the most dreaded disease in current/former athletes as it is currently considered incurable, invariably lethal, and is known to strike athletes in much higher rates than the general population. Medicine claims that about 10% of the ALS cases...
  17. haidut

    SSRI drug use during pregnancy linked (again) to autism

    I don't think the topic needs much of an introduction. At this point, the only people who deny the causal link between SSRI use by pregnant or soon-to-become pregnant women and autism in their children are either pharma employees...or doctors who receive so much money from pharma companies to...
  18. haidut

    Ubiquitous food dye causes inflammatory bowel disease (IBD)...by increasing serotonin

    It is rare these days to get a so-called "one-two punch" study. Namely, a study that not only discovers that instead of a genetic (medicine's favorite) there is a purely environmental (and man-made at that) cause of yet another chronic, degenerative conditions medicine considers incurable, but...
  19. cs3000

    Aluminium at "tolerable" human intakes causes gut inflammation & colon damage, higher doses ulcerative colitis, lower doses gut pain

    Yesterday i noticed dark grey residue on a pan again after scouring with a metal pad & cleaning it with some kitchen tissue. This stuff is likely Aluminium , which is damaging in the gut >10mg, & brain...
  20. haidut

    Finasteride causes gut inflammation, high serotonin, low dopamine; allopregnanolone may treat

    A great new study, which goes a long way towards explaining the dreaded post-finasteride syndrome (PFS). Currently, medicine does not recognize PFS as a formal disease and in fact attempts to gaslight the patients with PFS into believing they are simply mentally ill and in need of SSRI drugs...
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