Evaluation Of Natural Products On Inhibition Of (COX-2) & Nitric Oxide

Discussion in 'Scientific Studies' started by Lewis Acid, Mar 18, 2020.

  1. Lewis Acid

    Lewis Acid Member

    Mar 26, 2019
    Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells.

    Inhibition of COX-2 activity:
    Aristolochia debilis, Cinnamomum cassia, Cinnamomum loureirii, Curcuma zedoaria (Ginger Family), Eugenia caryophyllata (Cloves), Pterocarpus santalius (Sandalwood), Rehmania glutinosa and Tribulus terrestris showed potent inhibition of COX-2 activity.

    Inhibitors of iNOS activity:
    A. debilis (Green Toad), Caesalpinia sappan, Curcuma longa (Turmeric), C. zedoaria (Ginger Family), Daphne genkwa and Morus alba (Mulbery) were also considered as potential inhibitors of iNOS activity.