Evaluation Of Natural Products On Inhibition Of (COX-2) & Nitric Oxide

Discussion in 'Scientific Studies' started by Lewis Acid, Mar 18, 2020.

  1. Lewis Acid

    Lewis Acid Member

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    Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells.

    Inhibition of COX-2 activity:
    Aristolochia debilis, Cinnamomum cassia, Cinnamomum loureirii, Curcuma zedoaria (Ginger Family), Eugenia caryophyllata (Cloves), Pterocarpus santalius (Sandalwood), Rehmania glutinosa and Tribulus terrestris showed potent inhibition of COX-2 activity.

    Inhibitors of iNOS activity:
    A. debilis (Green Toad), Caesalpinia sappan, Curcuma longa (Turmeric), C. zedoaria (Ginger Family), Daphne genkwa and Morus alba (Mulbery) were also considered as potential inhibitors of iNOS activity.
     
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