ddjd
Member
- Joined
- Jul 13, 2014
- Messages
- 6,734
MSM has been shown to decrease the production of nitric oxide (NO) and mitochondrial ROS, decreasing initial levels of oxidative stress.
I have long suspected that the root cause of hair loss is high nitric oxide (and estrogen, cortisol), and low CO2.
I believe Red Light, Methylene Blue and Emodin, which all dissociate Nitric Oxide from Cytochrome C Oxidase are the most effective tools in the fight against hair loss.
I now suspect that MSM may also possess similar properties due to scientific literature proving that it reduces Nitric Oxide, and the astoundingly large anecdotal evidence that it halts hair loss and stimulates new hair growth.
STUDIES:
The anti-inflammatory effects of methylsulfonylmethane on lipopolysaccharide-induced inflammatory responses in murine macrophages. - PubMed - NCBI
"MSM significantly inhibited the release of nitric oxide and prostaglandin E(2) by alleviating the expression of inducible nitric oxide synthase and cyclooxygenase-2 in LPS-stimulated RAW264.7 cells."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372953/
"MSM can also diminish the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) through suppression of NF-κB; thus lessening the production of vasodilating agents such as nitric oxide (NO) and prostanoids [86]. NO not only modulates vascular tone [92] but also regulates mast cell activation [93]; therefore, MSM may indirectly have an inhibitory role on mast cell mediation of inflammation. "
I have long suspected that the root cause of hair loss is high nitric oxide (and estrogen, cortisol), and low CO2.
I believe Red Light, Methylene Blue and Emodin, which all dissociate Nitric Oxide from Cytochrome C Oxidase are the most effective tools in the fight against hair loss.
I now suspect that MSM may also possess similar properties due to scientific literature proving that it reduces Nitric Oxide, and the astoundingly large anecdotal evidence that it halts hair loss and stimulates new hair growth.
STUDIES:
The anti-inflammatory effects of methylsulfonylmethane on lipopolysaccharide-induced inflammatory responses in murine macrophages. - PubMed - NCBI
"MSM significantly inhibited the release of nitric oxide and prostaglandin E(2) by alleviating the expression of inducible nitric oxide synthase and cyclooxygenase-2 in LPS-stimulated RAW264.7 cells."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372953/
"MSM can also diminish the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) through suppression of NF-κB; thus lessening the production of vasodilating agents such as nitric oxide (NO) and prostanoids [86]. NO not only modulates vascular tone [92] but also regulates mast cell activation [93]; therefore, MSM may indirectly have an inhibitory role on mast cell mediation of inflammation. "