EustaceBagge
Member
I don't feel that the half life of t3 is short, I take it on an empty stomach in the morning and have no issues getting through the day really. Some places state that the half life of cynoplus is 24+ hours.Hey man. Great point! I had actually theorized that this could be happening myself!
However, I had come to understand that T3 itself actually supports the conversion of more T4 -> T3 rather than reverse T3, which was partly why I went with the 2:1 ratio in the first place, rather than the higher 4:1 ratio of NDT / cynoplus by itself (also because I did not want to jump straight on 40mcg of T4, but felt that 5mcg of T3 was so little that it was probably pointless).
But still, you could be correct. The only thing with T3 only is that it's half-life is so short... like a couple of hours or so. Difficult to use as a standalone therapy, especially when I feel this bad.
Triiodothyronine - an overview | ScienceDirect Topics
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But maybe your individual experience varies, just try t3 only and see whether you feel down later that day.