So I know many will agree that excitatory and inhibitory need to be in balance. However I’d say excitatory neurotransmitter action and excitotoxicity gets blamed too often.
In the sense that glycine supplements and gelatin and lowering glutamate etc lowering estrogen etc are often reccomended for many complaints. Will it help many. Yes sure.
So Ive done so many of these things and felt worse or no results. And then I really figured out my situation once i ramped up the glycine and gelatin. It’s just too damn inhibitory for me. I took magnesium glycinate often and gelatin, but kept blaming it on the magnesium. Until I switched forms.
Glycine constantly gives me a very slow heart beat/anxiety feeling. I often chalked it to up to oh it’s just relaxing me. But it just never feels right.
I stop glycine and gelatin and feel better right away. I’m confused. So I do some digging. I have very low norepinephrine(which ray speaks FAVORABLY of). Very low histamine, and very low estrogen. So it makes sense that I don’t need to tilt the balance towards inhibitory any more.
I realize the benefits of glycine though and it’s not like I have too much glycine, I just dont have enough excitatory action going on. So when I take gelatin I just add additional l-proline as that can convert to glutamate, or just straight glutamine itself/ and I’ve used l-histidine. All seem unpeaty but so be it. Works for me. WhAt I’m really trying to do long term is get my excitatory system working more. I think I’m lacking copper/copper toxic. Some sort of defiency Trying to boost the enzymes to support histamine/estrogen/glutamate. Might be the opposite of most ppls problems, but it is mine.
Can anyone relate ? I think this is why many feel a little wonky w glycine/gelatin. It’s just pushing them too far towards an inhibitory vibration and they’re already low energy and it’s slowing them down even more. Too calm. Where as for some ppl glycine can give energy. We’re all unique
In the sense that glycine supplements and gelatin and lowering glutamate etc lowering estrogen etc are often reccomended for many complaints. Will it help many. Yes sure.
So Ive done so many of these things and felt worse or no results. And then I really figured out my situation once i ramped up the glycine and gelatin. It’s just too damn inhibitory for me. I took magnesium glycinate often and gelatin, but kept blaming it on the magnesium. Until I switched forms.
Glycine constantly gives me a very slow heart beat/anxiety feeling. I often chalked it to up to oh it’s just relaxing me. But it just never feels right.
I stop glycine and gelatin and feel better right away. I’m confused. So I do some digging. I have very low norepinephrine(which ray speaks FAVORABLY of). Very low histamine, and very low estrogen. So it makes sense that I don’t need to tilt the balance towards inhibitory any more.
I realize the benefits of glycine though and it’s not like I have too much glycine, I just dont have enough excitatory action going on. So when I take gelatin I just add additional l-proline as that can convert to glutamate, or just straight glutamine itself/ and I’ve used l-histidine. All seem unpeaty but so be it. Works for me. WhAt I’m really trying to do long term is get my excitatory system working more. I think I’m lacking copper/copper toxic. Some sort of defiency Trying to boost the enzymes to support histamine/estrogen/glutamate. Might be the opposite of most ppls problems, but it is mine.
Can anyone relate ? I think this is why many feel a little wonky w glycine/gelatin. It’s just pushing them too far towards an inhibitory vibration and they’re already low energy and it’s slowing them down even more. Too calm. Where as for some ppl glycine can give energy. We’re all unique