M
metabolizm
Guest
The following snippets are taken from Ray's newsletter from 2008.
"Protective inhibition is one of the most important principles in biology. Heart disease, cancer, anxiety, allergies, epilepsy, degenerative nerve diseases, endocrine disorders, inappropriate inflammation and shock all involve defects of protective inhibition."
"Nitric oxide increases the ratio of glutamate to GABA ('the excitatory index')... while lowering mitochondrial energy production."
"The PUFA increase the susceptibility to excessive serotonin in the nervous system. One of the functions of the GABA system is to inhibit serotonergic nerves... Eating a diet with very low tryptophan content, and lacking PUFA, can support that function of the GABA system. The tea amino acid, thianine, suppresses serotonin by supporting the effects of GABA."
"It's important not to confuse the process of inhibition with psychological depression, which often involves an inability to inhibit the stress responses. The GABA system restrains the production of cortisol, which is typically increased in depression... The Diazepam type of antianxiety, antiseizure drug activates the GABA system, and this system is involved with the synthesis of steroids. Several varieties of that type of sedative increase the synthesis of neurosteroids, derived from progesterone. Progesterone and some of its metabolites protect the mitochondria, while acting with GABA to increase the state of inhibition."
"It [estrogen] is antagonistic to the GABA system, and promotes the action of excitatory transmitters, and increases formation of nitric oxide and prostaglandins."
"The saturated fats, rather than simply lacking the toxic and excitatory properties of the polyunsaturated fats, are being shown by many types of research to have protective, inhibitory, and restorative functions."
"Niacinamide, one of the B vitamins, happens to have GABAergic sedative activity."
"Maintaining an adequate supply of glucose is directly protective against excitotoxicity and helps to prevent stress reactions systemically."
"Although caffeine is a stimulant that can offset the sedative effects of GABA, it also functions as a neuroprotectant, protecting against some of the effects of glutamate. It is also a very good source of two other protective factor, magnesium and niacin. 'French-roast' (dark) coffee is an especially rich source of niacin, which might be responsible for the 'French paradox', the low incidence of heart disease in a country that doesn't follow the AHA's 'heart protective diet'."
"Protective inhibition is one of the most important principles in biology. Heart disease, cancer, anxiety, allergies, epilepsy, degenerative nerve diseases, endocrine disorders, inappropriate inflammation and shock all involve defects of protective inhibition."
"Nitric oxide increases the ratio of glutamate to GABA ('the excitatory index')... while lowering mitochondrial energy production."
"The PUFA increase the susceptibility to excessive serotonin in the nervous system. One of the functions of the GABA system is to inhibit serotonergic nerves... Eating a diet with very low tryptophan content, and lacking PUFA, can support that function of the GABA system. The tea amino acid, thianine, suppresses serotonin by supporting the effects of GABA."
"It's important not to confuse the process of inhibition with psychological depression, which often involves an inability to inhibit the stress responses. The GABA system restrains the production of cortisol, which is typically increased in depression... The Diazepam type of antianxiety, antiseizure drug activates the GABA system, and this system is involved with the synthesis of steroids. Several varieties of that type of sedative increase the synthesis of neurosteroids, derived from progesterone. Progesterone and some of its metabolites protect the mitochondria, while acting with GABA to increase the state of inhibition."
"It [estrogen] is antagonistic to the GABA system, and promotes the action of excitatory transmitters, and increases formation of nitric oxide and prostaglandins."
"The saturated fats, rather than simply lacking the toxic and excitatory properties of the polyunsaturated fats, are being shown by many types of research to have protective, inhibitory, and restorative functions."
"Niacinamide, one of the B vitamins, happens to have GABAergic sedative activity."
"Maintaining an adequate supply of glucose is directly protective against excitotoxicity and helps to prevent stress reactions systemically."
"Although caffeine is a stimulant that can offset the sedative effects of GABA, it also functions as a neuroprotectant, protecting against some of the effects of glutamate. It is also a very good source of two other protective factor, magnesium and niacin. 'French-roast' (dark) coffee is an especially rich source of niacin, which might be responsible for the 'French paradox', the low incidence of heart disease in a country that doesn't follow the AHA's 'heart protective diet'."