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- Aug 24, 2017
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- 5,858
No I have not experienced that it messes with my sleep or affects how I wake up even at 20mg daily.
The purpose of uncoupling is to increase heat and CO2 production. There are obviously a lot of other benefits to uncoupling but those are the main reasons. Uncoupling does improve mitochondrial function, but not directly restore it to normal function when broken, but can help indirectly by lowering ROS, RLS, RNS, etc. Creating new mitochondria is probably the best idea as then you'll have more prefectly working cells. Methylene blue increases it. MB and niacinamide keeps NAD/NADH ratio high which is essential cellular function, DNA repair, etc.
Keeping PUFAs low and increasing uncoupling will keep new mitochondrial happy.
The purpose of uncoupling is to increase heat and CO2 production. There are obviously a lot of other benefits to uncoupling but those are the main reasons. Uncoupling does improve mitochondrial function, but not directly restore it to normal function when broken, but can help indirectly by lowering ROS, RLS, RNS, etc. Creating new mitochondria is probably the best idea as then you'll have more prefectly working cells. Methylene blue increases it. MB and niacinamide keeps NAD/NADH ratio high which is essential cellular function, DNA repair, etc.
Keeping PUFAs low and increasing uncoupling will keep new mitochondrial happy.