unsubscribed
Member
Great thanks!Fast and slow COMT affect how quickly you deactivate catecholamines. PEMT is about endogenous choline synthesis.
I came across this.
"So is it all about getting enough choline? No! Certain supplements target PEMT directly.
S-adenosylmethionine or SAM-e enhances PEMT activity by supplying a methyl group. More SAM-e means your liver can make more choline and prevent deficiency [R, R].
According to limited clinical evidence, SAM-e may help with fatty liver, which is the most common sign of choline deficiency [R].
Keep in mind that most supplements can't be used to treat or prevent a medical condition."