RWilly
Member
- Joined
- Aug 30, 2018
- Messages
- 479
It could be a protective antioxidant from high iron:
Does bilirubin protect against hemochromatosis gene (HFE) related mortality? - PubMed - NCBI
"Taken together, our data suggest that the high levels of the antioxidant bilirubin may counteract the adverse effect of oxidative stress induced by iron overload."
Also, you might look into fat soluble vitamin deficiencies. A study in alcoholics, found that:
"All subjects with elevated serum bilirubin levels demonstrated depressed serum retinol levels. However, elevated molar ratios of retinol to RBP suggest that the carrying capacity of RBP was at times exceeded, even with low serum retinol levels. Follow-up of 12 subject after 2 weeks of hospitalization revealed significant individual changes in blood chemistry, but no general trends. Although this study emphasizes the need for individual evaluation and treatment, elevated bilirubin levels may be indicative of low serum retinol levels in the alcoholic."
And here is a study in infants:
Total serum bilirubin predicts fat-soluble vitamin deficiency better than serum bile acids in infants with biliary atresia. - PubMed - NCBI
"We found that TB [total bilirubin] was a better predictor of FSV [Fat-soluble vitamin] deficiency than SBA [serum bile acid] in infants with biliary atresia.
And speaking of babies, light therapy is used for babies who have jaundice.
Does bilirubin protect against hemochromatosis gene (HFE) related mortality? - PubMed - NCBI
"Taken together, our data suggest that the high levels of the antioxidant bilirubin may counteract the adverse effect of oxidative stress induced by iron overload."
Also, you might look into fat soluble vitamin deficiencies. A study in alcoholics, found that:
"All subjects with elevated serum bilirubin levels demonstrated depressed serum retinol levels. However, elevated molar ratios of retinol to RBP suggest that the carrying capacity of RBP was at times exceeded, even with low serum retinol levels. Follow-up of 12 subject after 2 weeks of hospitalization revealed significant individual changes in blood chemistry, but no general trends. Although this study emphasizes the need for individual evaluation and treatment, elevated bilirubin levels may be indicative of low serum retinol levels in the alcoholic."
And here is a study in infants:
Total serum bilirubin predicts fat-soluble vitamin deficiency better than serum bile acids in infants with biliary atresia. - PubMed - NCBI
"We found that TB [total bilirubin] was a better predictor of FSV [Fat-soluble vitamin] deficiency than SBA [serum bile acid] in infants with biliary atresia.
And speaking of babies, light therapy is used for babies who have jaundice.