Testosterone Optimization On RP-inspired Nutrition

youngsinatra

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I think the testosterone will increase further from now on, now that your LH increased.

Vitamin D can raise LH and also have been shown to improve sleep quality (so recovery & overall healing) and also helping digestion, so these could indirectly contribute to higher testosterone. Vitamin D deficiency can be a cause of low LH.

Prolonged stress, whether it’s emotional, physiological, environmental or chemical stress reduces LH.

NMDA agonism stimulates Gnrh (-> LH) and it‘s antagonism inhibits Gnrh/LH surges.
(https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1365-2826.1996.04462.x)

So the D-aspartic acid might play into the NMDA part there as it‘s an agonist of it. Maybe stay away from supplemental zinc and magnesium (or at least not above RDA levels) as these are natural NMDA antagonists.

Vitamin E might also play into this.
(Vitamin E stimulates luteinizing hormone-releasing hormone and ascorbic acid release from medial basal hypothalami of adult male rats - PubMed)
 
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GreekDemiGod

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@younggenius Hopefully. I now have proof that when LH and FSH increase, T production will follow.
I'm getting a full-night, non-interrupted sleep.
Could the VD have also been the reason for my lowered TSH?

About the D-aspartic acid, I read that it's only effective for short periods at a time.
I'm also trying to determine why my DHEA-S blood test was so low...
 

youngsinatra

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@younggenius Hopefully. I now have proof that when LH and FSH increase, T production will follow.
I'm getting a full-night, non-interrupted sleep.
Could the VD have also been the reason for my lowered TSH?

About the D-aspartic acid, I read that it's only effective for short periods at a time.
I'm also trying to determine why my DHEA-S blood test was so low...
I think vitamin D (25OHD) is inversely correlated with TSH, so yes, I think it’s possible.

Low DHEA is associated with burnout in young people, so prolonged chronic stress can be a potential cause of low DHEA, because the body preferentially converts pregnenolone into progesterone (instead of DHEA) to produce cortisol in that case.
 

BigShoes

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Guys, something great happened. Today's results from the lab arrived, there are significant improvements across the board for all parameters. A lot changed from 30 May to 13 June, less than 2 weeks.

Total Testosterone went from 192 ng/dL to 484 ng/dL. My highest T levels registered! It more than doubled in 2 weeks
Serum Cortisol went from 464 nmol/L to 416 nmol.L
Estradiol
went from 13.3 pg/mL to 21.9 pg/mL
FSH went from 1.97 mUI/ml to 2.77 mUI/mL
LH
from 2.62 mIU/ml to 5.24 mUI/mL
Prolactin
went down from 284 to 207 uUI/mL
TSH went down from 2.45 to 1.62 uUI/mL

Changes I've implemented

DHEA 25mg(only been on it for 4 days)
Vitamin D 15k IU
Vitamin E 300 IU(raises LH and FSH?)
D-Aspartic Acid(LH, FSH)

more eggs and liver(Retinol?) as per @Hans advice
Diet consists of: meat, eggs, fruits, raw honey. Zero starch/ gluten, zero dairy.

These seem like really great improvemnts. My testosterone increased by, my LH and FSH which were very low, now are in the middle range and signalling the body to produce. But why? The DHEA would be prime suspect, but I've only been taking it for 4 days. It would also explain the slight increase in E2.

Is it fair to assume this confirms that I do not have secondary hypogonadism? I really want to avoid going the TRT route.
Something was keeping my LH and FSH low and I have to find out why.
TSH went down to under 1 and I have no idea why. Is it the Vitamin D? The DHEA?

@Hans @youngsinatra
This is so awesome dude. Keep going.
 
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GreekDemiGod

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Guys, something great happened. Today's results from the lab arrived, there are significant improvements across the board for all parameters. A lot changed from 30 May to 13 June, less than 2 weeks.

Total Testosterone went from 192 ng/dL to 484 ng/dL. My highest T levels registered! It more than doubled in 2 weeks
Serum Cortisol went from 464 nmol/L to 416 nmol.L
Estradiol
went from 13.3 pg/mL to 21.9 pg/mL
FSH went from 1.97 mUI/ml to 2.77 mUI/mL
LH
from 2.62 mIU/ml to 5.24 mUI/mL
Prolactin
went down from 284 to 207 uUI/mL
TSH went down from 2.45 to 1.62 uUI/mL

Changes I've implemented

DHEA 25mg(only been on it for 4 days)
Vitamin D 15k IU
Vitamin E 300 IU(raises LH and FSH?)
D-Aspartic Acid(LH, FSH)

more eggs and liver(Retinol?) as per @Hans advice
Diet consists of: meat, eggs, fruits, raw honey. Zero starch/ gluten, zero dairy.

These seem like really great improvemnts. My testosterone increased by, my LH and FSH which were very low, now are in the middle range and signalling the body to produce. But why? The DHEA would be prime suspect, but I've only been taking it for 4 days. It would also explain the slight increase in E2.

Is it fair to assume this confirms that I do not have secondary hypogonadism? I really want to avoid going the TRT route.
Something was keeping my LH and FSH low and I have to find out why.
TSH went down to under 1 and I have no idea why. Is it the Vitamin D? The DHEA?

@Hans @youngsinatra
Updating with another result from yesterday:
DHEA-S went from 143 to 207. Amazing how fast things can change.

@BigShoes Thanks, I'm excited.

Another change that I've forgot to mention is that I have also reduced the number of workouts from 4-5 per week to 3.
 

Sefton10

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Oct 19, 2019
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Were the tests done by the same lab? Not wanting to rain on any parades, I’ve just seen in the past how the same tests can get quite different results in different labs.
 

cs3000

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Jul 27, 2022
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UK
Guys, something great happened. Today's results from the lab arrived, there are significant improvements across the board for all parameters. A lot changed from 30 May to 13 June, less than 2 weeks.
Total Testosterone went from 192 ng/dL to 484 ng/dL. My highest T levels registered! It more than doubled in 2 weeks
Serum Cortisol went from 464 nmol/L to 416 nmol.L
Estradiol
went from 13.3 pg/mL to 21.9 pg/mL
FSH went from 1.97 mUI/ml to 2.77 mUI/mL
LH
from 2.62 mIU/ml to 5.24 mUI/mL
Prolactin
went down from 284 to 207 uUI/mL
TSH went down from 2.45 to 1.62 uUI/mL
Changes I've implemented
DHEA 25mg(only been on it for 4 days)
Vitamin D 15k IU
Vitamin E 300 IU(raises LH and FSH?)
D-Aspartic Acid(LH, FSH)

more eggs and liver(Retinol?) as per @Hans advice
Diet consists of: meat, eggs, fruits, raw honey. Zero starch/ gluten, zero dairy.
These seem like really great improvemnts. My testosterone increased by, my LH and FSH which were very low, now are in the middle range and signalling the body to produce. But why? The DHEA would be prime suspect, but I've only been taking it for 4 days. It would also explain the slight increase in E2.
Is it fair to assume this confirms that I do not have secondary hypogonadism? I really want to avoid going the TRT route.
Something was keeping my LH and FSH low and I have to find out why.
TSH went down to under 1 and I have no idea why. Is it the Vitamin D? The DHEA?
Updating with another result from yesterday:
DHEA-S went from 143 to 207. Amazing how fast things can change.
@BigShoes Thanks, I'm excited.
Another change that I've forgot to mention is that I have also reduced the number of workouts from 4-5 per week to 3.
decent have you been taking that dhea orally on empty stomach?
 
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GreekDemiGod

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@cs3000 Yes, orally, not always on empty stomach.
But I don’t think it’s just the Dhea, I’ve only been taking it for 4 days before testing.
But my voice got deeper once I started taking it, that also happened to me in the past on Pansterone.
 

-Luke-

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Nice autofill Freudian slip.

But seriously, great news that you were able to turn things around in such a short time. And your perception and symptoms seem to reflect the change in the lab values. After years it would be awesome if you were able to make long-lasting changes.
 
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GreekDemiGod

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One sign of increasing Test in me is a much deeper voice. My normal voice is not that deep/ masculine, when I started on DHEA last Friday, it started getting deeper. And I also have that effect within minutes of applying either Kuinone or Pansterone on the testicles.
I'm too cautious with using Pansterone, I've had mixed experiences with it in the past, it feels like it's making my flaccid really soft, but I still get a proper erection if properly stimulated.
 
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GreekDemiGod

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Frequency of morning erections has increased. Hardness has also increased to almost optimal levels.
I was on vacation last week at the sea, spent a lot of time chilling in the sun.
 
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GreekDemiGod

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So I went back to the endocrinologist with the results of the investigations:

Testicular ultrasound - NORMAL
Sperm analysis- NORMAL, but sperm count a little bit sub-optimal, he'd like to see that go higher.

After he saw my latest blood tests, with increased T, he said he can't consider TRT anymore. Said it was a transient hypogonadism. Also said something about sperm cells/ fertility cycle lasting 3 months. He was more concerned about the fertility angle than my ED symptoms.
He also said that psychological stress/ depression can lower T.
Said that T levels are pulsatory and a more accurate measurement would be to take 3 blood samples at 30m intervals each and mix/ average the results together.
He recommended a specific multivitamin formula for men that is good for increasing fertility/ Testosterone and said to take that for a month, then one month break, then another month. Then do another sperm analysis after 3 months.

This is the product. You can translate the page in English.
These are the active ingredients:

  • L-Carnitine - 500mg
  • N-Acetyl L-Carnitine - 250mg
  • Vitamin E - 100mg (1000% NRV* )
  • Coenzyme Q10 - 100mg
  • Selenium - 90μg (164% NRV*)
  • Zinc - 15mg (200% NRV*)
  • Copper - 2mg (200% NRV*)
  • L-glutathione - 50mg
  • Lycopene (tomato extract standardized to 6% lycopene) - 4mg
  • Folate group (folic acid 200μg, active folate 200μg) - 400μg (200% NRV*)
  • L-arginine - 200mg
  • Vitamin D - 50 μg (2000IU) – (1000% NRV*)
  • Myo Inositol - 500mg

In the meantime, I will stick increasing nutrient density(eggs, liver) and all the other recent measures that I've written about.
 
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GreekDemiGod

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Yeah buddy. I'm looking forward to your next test.
I am scheduled for blood tests in 2 days. Luckily my insurance covers most of it, else I wouldn’t be testing so often.
It will be useful to see if talking Pansterone and/ or Kuinone had any effects, I added those since last time.
 
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GreekDemiGod

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Do you guys have any experiences with Clomid or HCG monotherapy? I'm thinking of asking my endocrinologist to prescribe me HCG. I believe it would do me good. My Leydig cells are working fine, my testicles are fine, it's just the signal from the pituitary to produce LH and FSH that's the problem.
 

youngsinatra

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Do you guys have any experiences with Clomid or HCG monotherapy? I'm thinking of asking my endocrinologist to prescribe me HCG. I believe it would do me good. My Leydig cells are working fine, my testicles are fine, it's just the signal from the pituitary to produce LH and FSH that's the problem.
HCG seems like a good idea for secondary hypogonadism. It maintains fertility in contrast to TRT.
 
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GreekDemiGod

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How’s it going, brother?
Same, not much has changed, honestly.
I’ve been taking DHEA, and Pansterone on and off in small doses.
What worries me is I noticed a reduction in ejaculate volume in the past 6 months or so. This can’t be good. I have got to really cut down on any form of artificial stumulation(porn) and masturbation.
Luckily I started dating someone recently, this should help a lot.
 
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