Randle Cycle, Insulin Resistence

[Felipe]

Hey :)
You mentioned in one of your podcasts, getting Insulin resistance via too much PUFA floating around. Did I get it right, by too many free fatty acids floating around, the body misinteprets Insulins signaling and eventually shuts it down which in turn leads to that resistance?

 

[paymanz]

Hey :)
You mentioned in one of your podcasts, getting Insulin resistance via too much PUFA floating around. Did I get it right, by too many free fatty acids floating around, the body misinteprets Insulins signaling and eventually shuts it down which in turn leads to that resistance?

I'm not sure exactly what's difference between PUFA,MUFA and SFA in this regard but high circulating free fatty acids in general causes insulin resistance.

 

[Felipe]

That PUFA are highly reactive and cause more damage,as far as I kmow. But thanks for your reply