I have posted here before about my 33 year old daughter who took Gabapentin for three weeks. It caused her hands and feet to swell and the swelling was very painful. She has been off of it a year and the pain and swelling are still with her. We have seen too many doctors to count and they all say the swelling should resolve. This has greatly impacted her life. Her health has basically been ruined by this drug. She took 300-600 3 times a day. She had no other side effects. It didnt even begin to cause her to be sleepy or high. We have researched the action of this drug. Some papers say Gabapentin raises Gaba and some say it blocks glutamate. She actually feels a little better take collegen and aminos so this seems like high GABA but magnesium seems to help as well. We are so lost. Has anyone here ever heard of this condition? Or dose anyone understand how this drug actually works. She seems irritated but has no energy some symptoms point to high Gaba and some point to low.