Prolactin As A Causative Agent In Prostate Cancer

Discussion in 'Scientific Studies' started by haidut, Mar 28, 2016.

  1. haidut

    haidut Member

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    Just wanted to post this, given the almost perfect correlation between prolactin and expression of estrogen "receptors" in tissues. If prolactin is a causative agent in prostate cancer, than the current idea of treating prostate cancer with estrogen is laughable. I also posted a study showing that PSA is raised by estrogen, not DHT or T.

    http://www.ncbi.nlm.nih.gov/pubmed/1724345

    "...With regard to Nodular Hyperplasia, once its hormone dependency is rated, it also appears to be stimulated by high levels of prolactin. The NH cell cultures with human prostate increase their growth, cell division, as well as the DNA synthesis. The aspects of the prolactin-prostate carcinoma interaction involve considering this hormone as a possible carcinogenic agent, emphasizing the existence of high plasma levels of this hormone in individuals with prostate carcinoma, where any androgen excess is considered a major factor at the genesis of this tumour, and prolactin increases indirectly its testicular synthesis. Also, prolactin itself stimulates the growth and development of carcinomatous human cell lines, increasing its effect in the presence of testosterone. For this reason, controlling this hormone levels becomes an element to have into consideration in the treatment and follow-up of these patients; also, the reevaluation of any drug therapy that, besides the initial goal pursued, does not maintain baseline prolactin levels. The association of anti-prolactin drugs has to be understood as a co-adjuvant therapy when there is androgenic deprivation, never as a single treatment."
     
  2. Kasper

    Kasper Member

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    I was wondering, what do you think about the prolactin increase after sex, is this harmful?
     
  3. OP
    haidut

    haidut Member

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    I think there are studies showing that after sex prolactin jumps higher than masturbation but it also drops much faster. Masturbation can keep prolactin moderately elevated for days.
     
  4. milk_lover

    milk_lover Member

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    Maybe it's a reason religions in general advise against masturbation? A friend of mine, when he masturbates the previous day, is a different person the next day. He looks angry and he gets very quite. His thinking skills plummet. He does eat a lot of PUFA and grains though. He told us about this one day over lunch with friends in a joking manner. There are several youtube TedX videos of hot women with revealing outfit informing the masses about how good for health it is to masturbate. Maybe there are paid by the porn industry.
     
  5. Soren

    Soren Member

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    Correct me if I'm wrong Haidut but the authors of this study, whilst acknowledging that prolactin is a cauasative agent they seem to be saying that its due to its effect on androgens which they say it enhances and that these androgens are the real cause of the prostate cancer. So they are falling back to the mainstream view and trying to twist the study results to fit their pre-established dogma.

    This is unfortunate given the real world cases of people having prostate cancer cured from the use of testosterone.

    Man 'cured' of prostate cancer after doctors shock tumour to death with testosterone
     
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