I have been taking Cypro for a while at 2mg/day. It seems to stop high cortisol & adrenaline in its tracks. However i find it increases anxiety/panicky feelings. This is similar feeling to when my prolactin gets high.
Many studies state that cypro actually low prolactin, however some show it actually increases it. This is what I feel could be happening to myself and others who dont respond well to cypro.
Many studies state that cypro actually low prolactin, however some show it actually increases it. This is what I feel could be happening to myself and others who dont respond well to cypro.
.Effect of cyproheptadine on TRH stimulated PRL and TSH release in man
A C EggeA C EggeAlan D RogolAlan D RogolM M VarmaM M VarmaR M BlizzardR M Blizzard
Journal of Clinical Endocrinology & Metabolism (Impact Factor: 6.21). 02/1977; 44(1):210-3. DOI: 10.1210/jcem-44-1-210
Source: PubMed
ABSTRACT
TRH-stimulated prolactin release was determined in four male volunteers with and without pre-treatment with cyproheptadine. All showed a marked increase in the TRH-mediated prolactin rise and a marked decrease in the TRH-mediated TSH rise when receiving cyproheptadine pre-treatment
Augmentation of prolactin response to TRH after cyproheptadine
A. C. Ammini, R. J. Dash, R. Sialy
Abstract
Serum PRL, TSH, T3 and T4 were estimated in the basal state and following iv bolus injection of 100 μg synthetic thyrotropin releasing hormone before and 7 days after cyproheptadine treatment in 5 healthy adult males. Only the PRL response to TRH was augmented after cyproheptadine. This is perhaps related to the antidopaminergic effect of cyproheptadine.
Cyproheptadine Stimulated Prolactin Release in the Young Turkey (Meleagris gallopavo)1
S. C. FEHRER, J. L. SILSBY and M. E. EL HALAWANI
+ Author Affiliations
Department of Animal Science, University of Minnesota, St. Paul, Minnesota 55108
Received January 1, 1984.
Abstract
Cyproheptadine (CHD) at doses of .1 to 10.0 mg/kg body weight produced a dose-related elevation in prolactin (PRL) and no change in luteinizing hormone (LH) levels. Cyproheptadine pretreatment failed to depress the quipazine (serotonin agonist)-induced PRL rise. Rather than inhibiting the serotonergic induction of PRL release in the young turkey, CHD exerted a stimulatory influence on PRL release through another mechanism.