J
j.
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Some have mentioned that after trying aspirin for a few days, they feel uncomfortable and stop. Could the main reason be more intestinal permeability due to aspirin?
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Source:Gut 1995;37:749-757Gastric adaptation to ASA enhances the mucosal resistance to injury by strong irritants probably as a result of restoration of gastric blood flow and increased cell proliferation that may result from increased mucosal expression of epithelial growth factor and it's receptors.
Blossom said:I'm not sure if this applies directly to the energy failure we are calling 'leaky gut' but I found this interesting:Source:Gut 1995;37:749-757Gastric adaptation to ASA enhances the mucosal resistance to injury by strong irritants probably as a result of restoration of gastric blood flow and increased cell proliferation that may result from increased mucosal expression of epithelial growth factor and it's receptors.
Forum member haidut has also posted on aspirin strengthening the gastric mucosa. I'm wondering if aspirin could help the gut be less leaky?
If aspirin strengthens the mucosa wouldn't that help with permeability? When I was first diagnosed with 'celiac disease' the research was indicating that a protein called zonulin was involved in opening the tight junctions in the intestine and increasing permeability. I'm not sure if that has been proven or not and that's about the limit of my knowledge on the topic.j. said:People with AIDS have twice the amount of serum PUFA as normal people. Aspirin restricts the release of fatty acids to the bloostream.
AIDS medicines also increase intestinal permeability. Is taking aspirin topically better to avoid more intestinal permeability?
j. said:People with AIDS have twice the amount of serum PUFA as non-infected people. Aspirin restricts the release of fatty acids to the bloostream.
AIDS medicines also increase intestinal permeability. Is taking aspirin topically better to avoid more intestinal permeability?
Blossom said:If aspirin strengthens the mucosa wouldn't that help with permeability? When I was first diagnosed with 'celiac disease' the research was indicating that a protein called zonulin was involved in opening the tight junctions in the intestine and increasing permeability. I'm not sure if that has been proven or not and that's about the limit of my knowledge on the topic.j. said:People with AIDS have twice the amount of serum PUFA as normal people. Aspirin restricts the release of fatty acids to the bloostream.
AIDS medicines also increase intestinal permeability. Is taking aspirin topically better to avoid more intestinal permeability?
j. said:If PUFAs weaken the immune system, and aspirin restricts their actions, then aspirin problem strengthens the immune system.
I heard that too about celiac and also that it's related to excess estrogen. I don't identify with that diagnosis the same way I used to but I still don't eat gluten. I'm healthier since discovering Peat and if I get cross-contaminated or eat something by accident (which is hard to do eating Peaty) I no longer get sick. That's positive. I personally like aspirin and use it daily as well. Everything I've read indicates it is helpful in numerous ways but I'm sure one can find contradictory views on everything. I'm just keeping it simple and sticking with Peat since he helped me figure out how to save my life. That approach has worked so far and I fully anticipate it will continue to work.Milklove said:Blossom said:If aspirin strengthens the mucosa wouldn't that help with permeability? When I was first diagnosed with 'celiac disease' the research was indicating that a protein called zonulin was involved in opening the tight junctions in the intestine and increasing permeability. I'm not sure if that has been proven or not and that's about the limit of my knowledge on the topic.j. said:People with AIDS have twice the amount of serum PUFA as normal people. Aspirin restricts the release of fatty acids to the bloostream.
AIDS medicines also increase intestinal permeability. Is taking aspirin topically better to avoid more intestinal permeability?
I am not going to pretend that I know a lot about celiac disease, but I heard that a thyroid defiency causes celiac disease.
It's the beautiful simplicity of Peat's work that has always resonated with me. Science can often be a challenge for lay people but fortunately Peat has made it simplified for those with a limited science background. If I can manage to heal coming from a dogmatic medical background I think anyone motivated to apply his work can do the same. In spite of not getting everything 'right' I have still experienced a level of healing I never thought possible and I haven't done anything out of the norm in my Peat inspired approach. The process of challenging our beliefs about healing and taking action on our own behalf is healing in itself in my opinion.j. said:I think the oh my god this is so complex attitude can lead to paralysis in action, and the problems can become worse while feeling perplexed doing nothing.