PUFA is the root of hypothyroidism, along with protein deficiencies and starvation/dieting/low cal among other things.
Depleting fat stores by becoming leaning(depleting PUFA), will go a long way to help liver detox estrogen. Increasing metabolism with sucrose, calcium, quality protein, salt, magnesium, sleep, sunlight, extreme low PUFA intake, and coconut oil will help.
Tissue-bound estrogen in aging
"Many kinds of liver impairment decrease its ability to excrete estrogen, and estrogen contributes to a variety of liver diseases. The work of the Biskinds in the 1940s showed that a dietary protein deficiency prevented the liver from detoxifying estrogen. Hypothyroidism prevents the liver from attaching glucuronic acid to estrogen, and so increases the body’s retention of estrogen, which in turn impairs the thyroid gland’s ability to secrete thyroid hormone. Hypothyroidism often results from nutritional protein deficiency."