LeeLemonoil
Member
- Joined
- Sep 24, 2016
- Messages
- 4,265
Seems like Tianeptine is helpful for mood-disorders not least because anti-inflammatory actions directly in brain structures stemming from protection against LPS.
Chronic administration of tianeptine balances lipopolysaccharide-induced expression of cytokines in the spleen and hypothalamus of rats. - PubMed - NCBI
Anti-inflammatory properties of tianeptine on lipopolysaccharide-induced changes in microglial cells involve toll-like receptor-related pathways. - PubMed - NCBI
The latter publication was retracted, because of formal issues not the validity of the findings.
Chronic administration of tianeptine balances lipopolysaccharide-induced expression of cytokines in the spleen and hypothalamus of rats. - PubMed - NCBI
Anti-inflammatory properties of tianeptine on lipopolysaccharide-induced changes in microglial cells involve toll-like receptor-related pathways. - PubMed - NCBI
The latter publication was retracted, because of formal issues not the validity of the findings.