Lots of hypotheses in this thread, so read with an open mind. There are just ideas and a way to look at things, not telling people to stop taking vit K or something. Also, this is about chronic usage and not about using these substances just once or a few times to break out of a stress state and then stopping them.
On a spiritual level, I think issues like high cortisol, nitric oxide, calcification mean that you have lessons to learn in life. They only happen if your life is led in a way such that your brain is not following your heart (leading to chronic hyperventilation). So if you take substances that lower NO or fix calcification, you have to make sure you're not taking a "shortcut substance" that heals you without making you learn the lessons you need to learn. You could say that there's no point in "learning lessons" when you could be healthy immediately by just taking a few supplements, but I think if you learn these lessons, then once you're healed your quality of life will be much greater/deeper than it would have been than if you had just relied on the supplement.
And I think the way to know whether something is a short-cut substance is to know whether or not it raises metabolic rate indefinitely. For example, although pregnenolone might temporarily raise metabolism and appetite (by lowering stress hormones and cortisol), you can take unlimited quantities without any effects, so it's not actually raising metabolic rate the way thyroid does. So it's a "short-cut" substance. Methylene blue is the same, by lowering NO it might temporarily turn on a metabolism that has been blocked by excess NO, but after the initial dose, you can take basically unlimited quantities without a raise in metabolism. Same with vitamin K (Dr. Peat has mentioned there is no "upper limit" to vitamin K dosage).
In contrast, things like coffee, aspirin, thyroid do raise metabolic rate infinitely the more you take them; the more coffee you drink or the more thyroid you take, the higher your temperature, and the more aspirin you take, the more you deplete nutrients like vit K and glycine. They don't "plateau" like pregnenolone/vitamin K/methylene blue. What that means is that whereas pregnenolone/methylene blue/vitamin K are "shortcut substances" that make you healthy without making you learn the lessons you need to learn, these substances make you healthy by making you learn needed lessons at an accelerated pace.
I have 0 evidence to back this up, but it just came to me and made sense to me in my head. (But it could also be utter nonsense.) Thoughts?
On a spiritual level, I think issues like high cortisol, nitric oxide, calcification mean that you have lessons to learn in life. They only happen if your life is led in a way such that your brain is not following your heart (leading to chronic hyperventilation). So if you take substances that lower NO or fix calcification, you have to make sure you're not taking a "shortcut substance" that heals you without making you learn the lessons you need to learn. You could say that there's no point in "learning lessons" when you could be healthy immediately by just taking a few supplements, but I think if you learn these lessons, then once you're healed your quality of life will be much greater/deeper than it would have been than if you had just relied on the supplement.
And I think the way to know whether something is a short-cut substance is to know whether or not it raises metabolic rate indefinitely. For example, although pregnenolone might temporarily raise metabolism and appetite (by lowering stress hormones and cortisol), you can take unlimited quantities without any effects, so it's not actually raising metabolic rate the way thyroid does. So it's a "short-cut" substance. Methylene blue is the same, by lowering NO it might temporarily turn on a metabolism that has been blocked by excess NO, but after the initial dose, you can take basically unlimited quantities without a raise in metabolism. Same with vitamin K (Dr. Peat has mentioned there is no "upper limit" to vitamin K dosage).
In contrast, things like coffee, aspirin, thyroid do raise metabolic rate infinitely the more you take them; the more coffee you drink or the more thyroid you take, the higher your temperature, and the more aspirin you take, the more you deplete nutrients like vit K and glycine. They don't "plateau" like pregnenolone/vitamin K/methylene blue. What that means is that whereas pregnenolone/methylene blue/vitamin K are "shortcut substances" that make you healthy without making you learn the lessons you need to learn, these substances make you healthy by making you learn needed lessons at an accelerated pace.
I have 0 evidence to back this up, but it just came to me and made sense to me in my head. (But it could also be utter nonsense.) Thoughts?
