My List of Actions to Prevent or Cure COVID-19???

md_a

Member
Joined
Aug 31, 2015
Messages
468
The nocebo and placebo effect is very strong, the daily indoctrination that is done through the media and social networks is difficult to control and avoid, and we can hardly know what is true and what is false. Certainly chemical experiments are done as biological weapons, and we all know that we live in a super polluted environment, from food, food, air, clothes, electronics, furniture, so the degree of toxicity is huge and so we are bombarded and programmed daily to inflammation. The saddest part is that we have been infected with vaccines with all kinds of dangerous substances since we were born. It is quite clear that a clean environment, without toxicity and without dubious people who experiment on us for profit and control, we would have enjoyed the peace of a normal life. But because we are caught in this dirty and vicious game, preventively I made a list of `anti-covid` protection, but without working too hard on it. Intuitively I have accumulated some information that I think could be useful in this context.

Methylene blue (1mg -15 mg per day) and related quinones such as EMODIN (from Aloe vera, Rhubarb, Cascara Sagrada) and vitamin K, ubiquinone, tetracycline, minocycline, azithromycin, erythromycin, Pau D'Arco - lapacho, etc.) have direct effects against many versions of coronavirus.
Methylene blue used in combination with light / sun treatment, is more efficient, but not needed, because methylene blue itself is quite potent virucidal.

Quinine inhibited SARS-CoV-2 infection more effectively than chloroquine (CQN) and hydroxychloroquine (H-CQN) and is less toxic.

Inhibiting inflammation with marmalade:

Naringenin is a powerful inhibitor of SARS-CoV-2

Apigenin and Quercetin are able to inhibit the 3CLpro activity up to 92% and 52%. This enzyme is one of the proteins responsible for this coronaviral replication.

“Orange juice contains the anti-inflammatory chemicals naringin and naringenin, which protect against endotoxin by suppressing the formation of nitric oxide and prostaglandins (Shiratori, et al., 2005).” Ray Peat

“Substances that inhibit inflammation are likely to also inhibit excessive collagen synthesis, serotonin secretion, and the formation of estrogen. Besides aspirin, some effective substances are apigenin and naringenin, found in oranges and guavas. These flavonoids also inhibit the formation of nitric oxide and prostaglandins, which are important for inflammation and carcinogenesis (Liang, et al., 1999).” Ray Peat


Anti-serotonin / anti-endotoxin chemicals such as Ciproheptadine and Benadryl have anti-viral effects even against viruses considered lethal.
Famotidine - The known on-target activity of famotidine considered the known primary mechanism of action is as an antagonist of the histamine H2 receptor.
Methylene blue in large quantities can have harmful serotonergic effects and ciproheptadine which is a potent antiviral should control for any adverse effects from higher doses of methylene blue.
Niacinamide is also a powerful antiviral.
Pau D’arco tea is anti-viral, antimicrobial, antibacterial, anti-fungal, anti-inflammatory, analgesic, antioxidant, anti-aging and supports metabolism.
Pure Pau D’arco peel is known for its healing properties through naphthoquinone called Beta-lapachone.
Glycine / gelatine is antiviral.
Antiparasitic ivermectin destroys COVID-19 ???
Chronic viral infection is usually due to high cortisol and endotoxin-promoting estrogen. Estrogens in food / estrogenic toxins in the environment activate retroviruses. Increased adrenaline suppresses the immune system and both increase vulnerability to viral infection. Unsaturated fats (omega 3 and 6), carotenes stimulate estrogen through aromatase.
The "virus" does not kill, but the immune reaction is what causes a cycle of inflammation (cytokine storm), which can lead to the death of the infected person. If there is a cytokine storm, then beta-blockers: clonidine, propranolol give the body a better chance to fight.
Excess iron is involved in the cytokine storm.
L-Theanine, aspirin, niacinamide, salt, honey.
Sun / Vitamin D / light treatment, vitamin K, vitamin E, Thyroid, Natural progesterone, Pregnenolone, easily digestible foods: sufficient protein in combination with fruit, Maple syrup (Maple Syrup), avoidance of PUFA (omega 3 and 6 ), Iron avoidance, Iron chelation; honey, salt, coffee, aspirin, niacinamide, L-Theanine and glycine / gelatine, lactoferrin, vitamin C, oregano oil, baking soda, magnesium oil, zinc, vitamin B1, B2, B6, medicinal charcoal (absorbs toxins) , chamomile tea.
Gargle with salt and lemon a very effective solution, aerosols with salt, aerosols with baking soda, with Methylene Blue. Hydrogen Peroxide Nebulization???

When used in sublingual and nebulised form Methylene Blue helps remarkably in clearing alveolar capillary block.

Covid patients show resemblance to methemoglobinemia. MB is considered an approved drug of choice for methemoglobinemia. Additionally, M.B. has a strong antifibrotic action and is very fast acting.

Given the above presentations, Methylene Blue can be used as a treatment to all Coronavirus symptomatic patients & as a prophylactic drug to all vulnerable population. Used in low dosage (as prescribed below) it shows no significant side effects (less than 2% of patients complained of irritation in the nose/nausea for a day which subsided on its own). Given its low cost, it is also a viable regime for poorer countries like India. A number of patients (with varying levels of respiratory distress) have been treated using MB in nebulised/sub-lingual for over the course of my years of practice.

Primary course of administration is in Nebulized form and sublingually together. For patients with severe Cyanosis (oxygen levels less than 85%), IV may be required based on the clinical condition of the patient.

Administration steps as below (under medical supervision only as MB is known to be toxic in incorrect dosages)

0.1% Methylene Blue to be administered as inhalation through a nebulizer (Primary line of treatment)

Nebulization to be given through a nasal mask

Sublingual administration will be as a supportive line of treatment



Riboflavin and endotoxin charcoal.
Copper prevents the spread of respiratory viruses.
Olive leaf extract have anti-viral properties.
Monolaurin has been found to be effective against viruses.
EMODINE: Anti-viral / anti-bacterial / Anti-parasitic / anti-fungal
Lidocaine has an antibacterial effect.
Lactoferrin has anti-fungal, anti-viral and anti-bacterial properties.
Policosanol is anti PUFA (polyunsaturated fat)
Hesperidin is a bioflavonoid in citrus fruit which has a similar effect as other Iron binding compounds. It is somewhat like lactoferrin for fruit, and in our bodies has the added benefit of protecting internal organs from elevated iron toxicity.
Hesperidin decrease AT1.
The virus activates the angiotensin receptor, so the receptor blockers are protective - losartan, telmisartan, etc. Progesterone is a natural inhibitor of that receptor.
The virus uses ACE2 (angiotensin 2 conversion enzyme) as a receptor and enters cells through the AT1 angiotensin receptor. Losartan, an angiotensin blocker, is an effective protection and has many other anti-inflammatory effects. Cinanserine a serotonin blocker and Ciproheptadine could help. Progesterone lowers the angiotensin receptor, but does not act immediately as losartan does.
Vitamin B1 decreases the type 1 angiotensin 2 receptor or AT1 receptor through which the virus has access to the cell.


"The role of our endogenous DNA mobile elements in stress, aging, and inflammation, and their structural similarity to viruses, suggests that substances that are helpful for stress-induced inflammation could be helpful for viral infections, and vice versa. All of the effective treatments for Covid-19 have had anti-inflammatory effects—angiotensin blockers, cinanserin (a serotonin blocker), antihistamines, naringenin, hesperidin, fisetin and other flavonoids (Clementi, et al., 2021; Bellavite and Donzelli, 2020; Mishra, et al., 2020; Jo, et al., 2020), progesterone (Jakovac, 2020), and calcium channel blockers (Solaimanzadeh, 2020; Jayaseelan VP and Paramasivam, 2020).
These substances reduce intracellular calcium and increase carbon dioxide in relation to oxygen and lactate, with the effect of reducing random and meaningless excitation and activation of tissues, making energy available for purposeful organized activities of the organism." Ray Peat

"The coronas, like polio, have a strong tendency to grow on the intestine (also heart, lungs, blood vessels), and the (or any) inflammation in the bowel releases large amounts of serotonin, histamine, and endotoxin into the blood, adding to any lung problem from direct infection.

The angiotensin system increases estrogen, prostaglandins, nitric oxide and other inflammation mediators, so many anti-inflammatory things help with this virus. Before big stringy, plugging clots form, the thin fibrin film that always coats red blood cells and the inside of capillaries begins getting thicker as the equilibrium between forming and dissolving the fibrin film shifts toward faster forming, and oxygenation of tissues lags behind deoxygenation of blood cells.

Lactic acid formation in response to hypoxia and stress signals adds to the inflammation of the lungs, causing them to take up water even if they aren’t infected."-Dr. Ray Peat

Focus on the induction of antibodies by vaccines to define immunity has led to a dangerous disregard for the basic facts of health. The present testing of a vaccine containing the RNA that specifies the most destructive spike protein of the corona virus, the part that inactivates our protective ACE2 enzyme, is being done in a culture that avoids consideration of the meaning of our massive endogenous system of RNA-responsive reverse transcriptases and retroelements. The consequences of incorporating the spike protein of the virus into our genetic repertoire are hard to imagine. The mindless activation of our huge epigenetic system of retroelements, with no knowable benefits, should be stopped. – Ray Peat

The spike protein causes inflammation by inactivating the enzyme (ACE2) that inactivates angiotensin, so the spike protein essentially turns on our inflammatory system, the angiotensin system, and the RNA allows our own cells to manufacture spike protein, so we are being prepared to manufacture the activator of our own inflammatory system which is basically the only thing that causes people to die from Covid, if they die from it, mostly none of that diagnosis or determination of the cause of death, none of that has been done in a traditional scientific manner but to the extent that virus is harmful to week people, then is causing our body to produce the agent that kills people, and they ignore the fact that we have reverse transcriptase that can turn RNA to DNA and integrated it into our genes so that we can pass on the ability to destroy our defences against inflammation. - Ray Peat

For years, corona viruses have been known to bind to the angiotensin converting enzyme 2 (ACE2), and that enzyme has been known to have protective effects, destroying angiotensin, and losartan, an angiotensin receptor blocker, has been known to be protective against corona viruses. Angiotensin increases intracellular calcium, and losartan lowers intracellular calcium. In reaction to the new corona virus, a few groups responded quickly, treating successfully with anti-inflammatory things—losartan, cinanserin (a serotonin antagonist), aspirin, and azithromycin or erythromycin, which lower intracellular calcium. Aspirin’s effects overlap those of losartan, and it downregulates the angiotensin receptor, ATR1 (Mitra, et al., 2012). - Ray Peat

The problem is that our bodies can copy foreign RNA and DNA and incorporate the copies into our chromosomes. If they are genes for viral proteins, it’s possible that during a future stress, those foreign genes could be expressed throughout our body, creating overwhelming amounts of those toxic proteins. The copies could be inserted into sperm cells and eggs as well as body cells, forming part of future generations. No sane person would consider doing it, if they understood how our cells respond to alien nucleic acids. - Ray Peat


Ideal body temperature 37 C, pulse 75-90
 

Inaut

Member
Joined
Nov 29, 2017
Messages
3,620
agreed. Thanks for your helpful contributions!
 

RealNeat

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Joined
Jan 9, 2019
Messages
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HI
Dang great list. A good summary, it's amazing that the approach to this "illness" is similar to what Ray has been touting as the solution to many ailments over the years, but now the mainstream tier of alternative/ natural health is recognizing it. They however still don't have the biochemical and physiological explanations down as cohesively as Dr. Peat puts it. All of these compounds are beneficial even without a so called pandemic of a coronavirus.
 

pauljacob

Member
Joined
Mar 9, 2018
Messages
435
Thank you @md_a for this generous and potent contribution. I currently use a tincture of Pau D'arco to fight a stomach ulcer or virus. Would that be sufficient, or do I have to get the tea?

Also Ginger is missing from your impressive antiviral arsenal. According to a Healthline article "Ginger has been shown to have impressive antiviral activity thanks to its high concentration of potent plant compounds. Additionally, specific compounds in ginger, such as gingerols and zingerone, have been found to inhibit viral replication and prevent viruses from entering host cells.

 

GreenTrails

Member
Joined
Jul 31, 2020
Messages
169
The nocebo and placebo effect is very strong, the daily indoctrination that is done through the media and social networks is difficult to control and avoid, and we can hardly know what is true and what is false. Certainly chemical experiments are done as biological weapons, and we all know that we live in a super polluted environment, from food, food, air, clothes, electronics, furniture, so the degree of toxicity is huge and so we are bombarded and programmed daily to inflammation. The saddest part is that we have been infected with vaccines with all kinds of dangerous substances since we were born. It is quite clear that a clean environment, without toxicity and without dubious people who experiment on us for profit and control, we would have enjoyed the peace of a normal life. But because we are caught in this dirty and vicious game, preventively I made a list of `anti-covid` protection, but without working too hard on it. Intuitively I have accumulated some information that I think could be useful in this context.

Methylene blue (1mg -15 mg per day) and related quinones such as EMODIN (from Aloe vera, Rhubarb, Cascara Sagrada) and vitamin K, ubiquinone, tetracycline, minocycline, azithromycin, erythromycin, Pau D'Arco - lapacho, etc.) have direct effects against many versions of coronavirus.
Methylene blue used in combination with light / sun treatment, is more efficient, but not needed, because methylene blue itself is quite potent virucidal.

Quinine inhibited SARS-CoV-2 infection more effectively than chloroquine (CQN) and hydroxychloroquine (H-CQN) and is less toxic.

Inhibiting inflammation with marmalade:

Naringenin is a powerful inhibitor of SARS-CoV-2

Apigenin and Quercetin are able to inhibit the 3CLpro activity up to 92% and 52%. This enzyme is one of the proteins responsible for this coronaviral replication.

“Orange juice contains the anti-inflammatory chemicals naringin and naringenin, which protect against endotoxin by suppressing the formation of nitric oxide and prostaglandins (Shiratori, et al., 2005).” Ray Peat

“Substances that inhibit inflammation are likely to also inhibit excessive collagen synthesis, serotonin secretion, and the formation of estrogen. Besides aspirin, some effective substances are apigenin and naringenin, found in oranges and guavas. These flavonoids also inhibit the formation of nitric oxide and prostaglandins, which are important for inflammation and carcinogenesis (Liang, et al., 1999).” Ray Peat


Anti-serotonin / anti-endotoxin chemicals such as Ciproheptadine and Benadryl have anti-viral effects even against viruses considered lethal.
Famotidine - The known on-target activity of famotidine considered the known primary mechanism of action is as an antagonist of the histamine H2 receptor.
Methylene blue in large quantities can have harmful serotonergic effects and ciproheptadine which is a potent antiviral should control for any adverse effects from higher doses of methylene blue.
Niacinamide is also a powerful antiviral.
Pau D’arco tea is anti-viral, antimicrobial, antibacterial, anti-fungal, anti-inflammatory, analgesic, antioxidant, anti-aging and supports metabolism.
Pure Pau D’arco peel is known for its healing properties through naphthoquinone called Beta-lapachone.
Glycine / gelatine is antiviral.
Antiparasitic ivermectin destroys COVID-19 ???
Chronic viral infection is usually due to high cortisol and endotoxin-promoting estrogen. Estrogens in food / estrogenic toxins in the environment activate retroviruses. Increased adrenaline suppresses the immune system and both increase vulnerability to viral infection. Unsaturated fats (omega 3 and 6), carotenes stimulate estrogen through aromatase.
The "virus" does not kill, but the immune reaction is what causes a cycle of inflammation (cytokine storm), which can lead to the death of the infected person. If there is a cytokine storm, then beta-blockers: clonidine, propranolol give the body a better chance to fight.
Excess iron is involved in the cytokine storm.
L-Theanine, aspirin, niacinamide, salt, honey.
Sun / Vitamin D / light treatment, vitamin K, vitamin E, Thyroid, Natural progesterone, Pregnenolone, easily digestible foods: sufficient protein in combination with fruit, Maple syrup (Maple Syrup), avoidance of PUFA (omega 3 and 6 ), Iron avoidance, Iron chelation; honey, salt, coffee, aspirin, niacinamide, L-Theanine and glycine / gelatine, lactoferrin, vitamin C, oregano oil, baking soda, magnesium oil, zinc, vitamin B1, B2, B6, medicinal charcoal (absorbs toxins) , chamomile tea.
Gargle with salt and lemon a very effective solution, aerosols with salt, aerosols with baking soda, with Methylene Blue. Hydrogen Peroxide Nebulization???

When used in sublingual and nebulised form Methylene Blue helps remarkably in clearing alveolar capillary block.

Covid patients show resemblance to methemoglobinemia. MB is considered an approved drug of choice for methemoglobinemia. Additionally, M.B. has a strong antifibrotic action and is very fast acting.

Given the above presentations, Methylene Blue can be used as a treatment to all Coronavirus symptomatic patients & as a prophylactic drug to all vulnerable population. Used in low dosage (as prescribed below) it shows no significant side effects (less than 2% of patients complained of irritation in the nose/nausea for a day which subsided on its own). Given its low cost, it is also a viable regime for poorer countries like India. A number of patients (with varying levels of respiratory distress) have been treated using MB in nebulised/sub-lingual for over the course of my years of practice.

Primary course of administration is in Nebulized form and sublingually together. For patients with severe Cyanosis (oxygen levels less than 85%), IV may be required based on the clinical condition of the patient.

Administration steps as below (under medical supervision only as MB is known to be toxic in incorrect dosages)

0.1% Methylene Blue to be administered as inhalation through a nebulizer (Primary line of treatment)

Nebulization to be given through a nasal mask

Sublingual administration will be as a supportive line of treatment



Riboflavin and endotoxin charcoal.
Copper prevents the spread of respiratory viruses.
Olive leaf extract have anti-viral properties.
Monolaurin has been found to be effective against viruses.
EMODINE: Anti-viral / anti-bacterial / Anti-parasitic / anti-fungal
Lidocaine has an antibacterial effect.
Lactoferrin has anti-fungal, anti-viral and anti-bacterial properties.
Policosanol is anti PUFA (polyunsaturated fat)
Hesperidin is a bioflavonoid in citrus fruit which has a similar effect as other Iron binding compounds. It is somewhat like lactoferrin for fruit, and in our bodies has the added benefit of protecting internal organs from elevated iron toxicity.
Hesperidin decrease AT1.
The virus activates the angiotensin receptor, so the receptor blockers are protective - losartan, telmisartan, etc. Progesterone is a natural inhibitor of that receptor.
The virus uses ACE2 (angiotensin 2 conversion enzyme) as a receptor and enters cells through the AT1 angiotensin receptor. Losartan, an angiotensin blocker, is an effective protection and has many other anti-inflammatory effects. Cinanserine a serotonin blocker and Ciproheptadine could help. Progesterone lowers the angiotensin receptor, but does not act immediately as losartan does.
Vitamin B1 decreases the type 1 angiotensin 2 receptor or AT1 receptor through which the virus has access to the cell.


"The role of our endogenous DNA mobile elements in stress, aging, and inflammation, and their structural similarity to viruses, suggests that substances that are helpful for stress-induced inflammation could be helpful for viral infections, and vice versa. All of the effective treatments for Covid-19 have had anti-inflammatory effects—angiotensin blockers, cinanserin (a serotonin blocker), antihistamines, naringenin, hesperidin, fisetin and other flavonoids (Clementi, et al., 2021; Bellavite and Donzelli, 2020; Mishra, et al., 2020; Jo, et al., 2020), progesterone (Jakovac, 2020), and calcium channel blockers (Solaimanzadeh, 2020; Jayaseelan VP and Paramasivam, 2020).
These substances reduce intracellular calcium and increase carbon dioxide in relation to oxygen and lactate, with the effect of reducing random and meaningless excitation and activation of tissues, making energy available for purposeful organized activities of the organism." Ray Peat

"The coronas, like polio, have a strong tendency to grow on the intestine (also heart, lungs, blood vessels), and the (or any) inflammation in the bowel releases large amounts of serotonin, histamine, and endotoxin into the blood, adding to any lung problem from direct infection.

The angiotensin system increases estrogen, prostaglandins, nitric oxide and other inflammation mediators, so many anti-inflammatory things help with this virus. Before big stringy, plugging clots form, the thin fibrin film that always coats red blood cells and the inside of capillaries begins getting thicker as the equilibrium between forming and dissolving the fibrin film shifts toward faster forming, and oxygenation of tissues lags behind deoxygenation of blood cells.

Lactic acid formation in response to hypoxia and stress signals adds to the inflammation of the lungs, causing them to take up water even if they aren’t infected."-Dr. Ray Peat

Focus on the induction of antibodies by vaccines to define immunity has led to a dangerous disregard for the basic facts of health. The present testing of a vaccine containing the RNA that specifies the most destructive spike protein of the corona virus, the part that inactivates our protective ACE2 enzyme, is being done in a culture that avoids consideration of the meaning of our massive endogenous system of RNA-responsive reverse transcriptases and retroelements. The consequences of incorporating the spike protein of the virus into our genetic repertoire are hard to imagine. The mindless activation of our huge epigenetic system of retroelements, with no knowable benefits, should be stopped. – Ray Peat

The spike protein causes inflammation by inactivating the enzyme (ACE2) that inactivates angiotensin, so the spike protein essentially turns on our inflammatory system, the angiotensin system, and the RNA allows our own cells to manufacture spike protein, so we are being prepared to manufacture the activator of our own inflammatory system which is basically the only thing that causes people to die from Covid, if they die from it, mostly none of that diagnosis or determination of the cause of death, none of that has been done in a traditional scientific manner but to the extent that virus is harmful to week people, then is causing our body to produce the agent that kills people, and they ignore the fact that we have reverse transcriptase that can turn RNA to DNA and integrated it into our genes so that we can pass on the ability to destroy our defences against inflammation. - Ray Peat

For years, corona viruses have been known to bind to the angiotensin converting enzyme 2 (ACE2), and that enzyme has been known to have protective effects, destroying angiotensin, and losartan, an angiotensin receptor blocker, has been known to be protective against corona viruses. Angiotensin increases intracellular calcium, and losartan lowers intracellular calcium. In reaction to the new corona virus, a few groups responded quickly, treating successfully with anti-inflammatory things—losartan, cinanserin (a serotonin antagonist), aspirin, and azithromycin or erythromycin, which lower intracellular calcium. Aspirin’s effects overlap those of losartan, and it downregulates the angiotensin receptor, ATR1 (Mitra, et al., 2012). - Ray Peat

The problem is that our bodies can copy foreign RNA and DNA and incorporate the copies into our chromosomes. If they are genes for viral proteins, it’s possible that during a future stress, those foreign genes could be expressed throughout our body, creating overwhelming amounts of those toxic proteins. The copies could be inserted into sperm cells and eggs as well as body cells, forming part of future generations. No sane person would consider doing it, if they understood how our cells respond to alien nucleic acids. - Ray Peat


Ideal body temperature 37 C, pulse 75-90
Thank you for this information.
 

miquelangeles

Member
Joined
Mar 18, 2021
Messages
928
Good summary.

Also:

- selenium, very important too
- melatonin (Ray is not a fan but he says 1mg is safe; I'd say 5mg is fine too since you'd be taking it for a limited period during sickness; it was also part of Trump's treatment along with famotidine, vit D, zinc, aspirin, monoclonals)
- ranitidine is likely more effective than famotidine, since they had to falsify studies in order to take it off the market everywhere
- medicinal mushrooms such as Coriolus versicolor, Reishi etc
- onions
- plain hot water alone can stop almost any cold in its tracks if taken early, even better with some sugar or honey
- a lot of natural herbs, foods etc are antiviral but their mechanisms are overlapping
- it is important that people use herbs and natural remedies that they are familiar with and they have used in the past
- taking a new herbal supplement that you are even mildly allergic to (without knowing) during sickness will do more harm than good, because you will not be able to tell if the worsening is due to the virus or from the supplement
 

Motif

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Joined
Nov 24, 2017
Messages
2,757
That’s a lot of stuff.

Would you take all of it?
And the question is how much of it?

Still super sceptical, cause I took lots of recommended stuff and it did not improve my last two simple colds.

Also there’s quite a lot people in ray peat groups and the forum that had not too mild cases and even longterm symptoms.
 
P

Peatness

Guest
I would add Taurine to this list. It’s an angiotensin receptor blocker, anti-inflammatory agent, calcium channel blocker, heart/brain protective, and more.

"Magnesium, taurine, and niacinamide have many protective functions, and can help to reduce or reverse inflammatory and fibrogenic processes." Ray Peat
 
OP
md_a

md_a

Member
Joined
Aug 31, 2015
Messages
468
Thank you @md_a for this generous and potent contribution. I currently use a tincture of Pau D'arco to fight a stomach ulcer or virus. Would that be sufficient, or do I have to get the tea?

Also Ginger is missing from your impressive antiviral arsenal. According to a Healthline article "Ginger has been shown to have impressive antiviral activity thanks to its high concentration of potent plant compounds. Additionally, specific compounds in ginger, such as gingerols and zingerone, have been found to inhibit viral replication and prevent viruses from entering host cells.

I have no idea because being more expensive I did not use Pau D'arco, instead I often make tea from ginger, chamomile and dandelion. (Common dandelion (Taraxacum officinale) efficiently blocks the interaction between ACE2 cell surface receptor and SARS-CoV-2 spike protein D614, mutants D614G, N501Y, K417N and E484K in vitro)
 

aaron2211

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Joined
Oct 21, 2021
Messages
5
Location
Australia
I would add Taurine to this list. It’s an angiotensin receptor blocker, anti-inflammatory agent, calcium channel blocker, heart/brain protective, and more.

"Magnesium, taurine, and niacinamide have many protective functions, and can help to reduce or reverse inflammatory and fibrogenic processes." Ray Peat
Interesting, I have been taking magnesium taurate recently so this is welcomed, and beginning niacinamide soon. Seems to be a high content of taurine in this supplement and probably won’t be taking it for a too lengthy duration. New to the forum but have seen many of your posts and thank you for your input. Also in Australia so I keep up to date with that psycho-Australia one too. ;)
 
Last edited:
OP
md_a

md_a

Member
Joined
Aug 31, 2015
Messages
468
That’s a lot of stuff.

Would you take all of it?
And the question is how much of it?

Still super sceptical, cause I took lots of recommended stuff and it did not improve my last two simple colds.

Also there’s quite a lot people in ray peat groups and the forum that had not too mild cases and even longterm symptoms.
Although it is very difficult in the city, I try to focus on a proper and sufficient diet and then, depending on the symptoms, I turn to that list plus other ideas that come to my mind. The quantity differs depending on what I have available. By my own logic, when the thyroid condition (metabolic rate decreases) suffers from countless stressors we are vulnerable to all kinds of toxins, the body's reaction is to maintain a balance through elimination and recovery, and its ability to eliminate toxins and heal is related with the level of energy, and this energy we receive from the sun and food, and because we live mostly in the city, the degree of pollution and toxicity is huge, and food is plasticized and full of pesticides, so the body's ability to stay in -a healthy euphoric state is difficult to obtain. My list is a set of `tricks` that I use and experiment with when I feel I need it, and when something doesn't work, I adjust as I accumulate other ideas. And of course, it gets more and more complicated as the degree of toxicity and radiation increases, and in the meantime, we are exposed to all sorts of genetic experiments plus the trauma of conditioning and deprivation of liberty.

What I mean is that each of us responds to inflammation through toxicity differently, depending on the level of stress, emotional stress, the body's resistance, the cleanest and sufficient diet, radiation, unsaturated fats accumulated in the tissue, heavy metals ...

I recently lived in my grandparents' village for 3 weeks, and I ate daily 5 litters of raw milk, gelatine soups, fruits. Clean air, exposure to natural light from morning to evening at bedtime, without radiation, deep and restful sleep. I felt very good and energetic, the quality of my skin and hair improved significantly.

Instead, in the city I have to put a lot of effort and resort to many tricks to feel as normal as possible with my health.

`My list` helps to calm the inflammation mediators so that they are not secreted excessively and together with a proper diet they should provide enough energy to the body to heal.



Mediators of inflammation:

Histamine, Bradykinin, Prostaglandins (PGE2, PGD2, and PGF2), NO, Leukotrienes (C4, D4, T4), Serotonin

A series of humoral alterations are a characteristic finding in sepsis, polytrauma, and other affections, which are often followed by an acute lung failure ARDS (adult respiratory distress syndrome) or multiple organ failure (MOF). Based on experimental and clinical findings, the cooperation of a variety of mediators and mediator systems are responsible for causing the disturbance of vascular tone and permeability and inducing the morphological transformation which finally may result in the failure of vital organs. Beside the classical mediators, such as catecholamines, histamine, serotonin, and bradykinin, increasing attention has recently focused on metabolites of arachidonic acid, cytokines, and products from circulating or resident inflammatory cells. Of all these humoral and cellular alterations, the activation and liberation of proteinases seems to play an essential role with regard to loss of capillary barrier function and interstitial edema formation.

Inflammation results in the release of mediators that cause vasodilation, increase microvascular permeability, and induce leukocyte infiltration.

An increase in serum C18 unsaturated free fatty acids is a predictor of the development of acute respiratory distress syndrome. Because activation of phospholipid-signaling pathways involving the acyl chains oleate and linoleate may initiate and amplify the inflammatory response, and thereby lead to the development of ARDS.

During intensive care treatment, patients with ARDS decrease their percentage plasma concentrations of total plasma linoleic acid, but increase their percentage concentrations of oleic and palmitoleic acids. As plasma linoleic acid concentrations decreased, there was usually an increase in plasma 4-hydroxy-2-nonenal (HNE) values, one of its specific peroxidation products, suggestive of severe oxidative stress leading to molecular damage to lipids.

Because activation of phospholipid-signaling pathways involving the acyl chains oleate and linoleate may initiate and amplify the inflammatory response, and thereby lead to the development of ARDS.

Increases in unsaturated serum acyl chain ratios differentiate between healthy and seriously ill patients, and identify those patients likely to develop ARDS. Thus, the serum acyl ratio may not only prospectively identify and facilitate the assessment of new treatments in patients at highest risk for developing ARDS, but may also lead to new insights about the pathogenesis of ARDS.

Arachidonic acid (AA), an unsaturated fatty acid directly from the diet or indirectly from the metabolism of linoleic acid, is released from the breakdown of cell membrane phospholipids by the action of the enzyme phospholipase A2. Numerous stimuli, ranging from simple mechanical to specific chemical stimulation may activate what has been named the arachidonic acid cascade.

Injury in ARDS involves the alveolar and pulmonary capillary epithelium. A cascade of cellular and biochemical changes is triggered by the specific causative agent. When initiated, this injury triggers neutrophils, macrophages, monocytes, and lymphocytes to produce various cytokines. The cytokines promote cellular activation, chemotaxis, and adhesion. The activated cells produce inflammatory mediators, including oxidants, proteases, kinins, growth factors, and neuropeptides, which initiate the complement cascade, intravascular coagulation, and fibrinolysis.

The cellular triggers result in vascular permeability to proteins, affecting the hydrostatic pressure gradient of the capillary. Elevated capillary pressure, such as the resulting from fluid overload or cardiac dysfunction in sepsis, increases interstitial and alveolar edema, which is evident in dependent lung areas and can be visualized as whitened area on X-rays. Alveolar closing pressure then exceeds pulmonary pressures, and alveolar closure and collapse begins.

In ARDS, fluid accumulation in lung interstitium, the alveolar spaces, and the small airways causes the lungs to stiffen, thus impairing ventilation and reducing oxygenation of the pulmonary capillary blood. The resulting injury reduces normal blood flow to the lungs. Damage can occur directly – by aspiration of gastric contents and inhalation of noxious gases – or indirectly – from chemical mediators released in response to systemic disease.

Platelets begin to aggregate and release substances, such as serotonin, bradykinin, and histamine, which attract and activate neutrophils. These substances inflame and damage the alveolar membrane and later increase capillary permeability. In the early stages, signs and symptoms may be undetectable.

Capillary permeability

Additional chemotactic factors released include endotoxins (such those present in septic states), tumor necrosis factor and interleukin-1. The activated neutrophils release several inflammatory mediators and platelet aggravating factors that damage the alveolar capillary membrane and increase capillary permeability.

Histamine and other inflammatory substances increase capillary permeability allowing fluids to move into the interstitial space. Consequently, the patient experience tachypnea, dyspnea, and tachycardia. As capillary permeability increases, proteins, blood cells, and more fluid leak out, increasing interstitial pressure and causing pulmonary edema. Tachycardia, dyspnea, and cyanosis may occur. Hypoxia (usually unresponsive to increasing fraction of inspired oxygen), decreased pulmonary compliance, crackles, and rhonchi develop. The resulting pulmonary edema and hemorrhage significantly reduce lung compliance and impair alveolar ventilation. The fluid in the alveoli and decreased blood flow damage surfactant in the alveoli. The reduces the ability of alveolar cells to produce more surfactant. Without surfactant, alveoli and bronchioles fill with fluid or collapse, gas exchange is impaired, and the lungs are much less compliant. Ventilation of the alveoli is further decreased. The burden of ventilation and gas exchange shifts to uninvolved areas of the lung, and pulmonary blood flow is shunted from right to left. The work of breathing is increased, and the patient may develop thick, frothy sputum and marked hypoxemia with increasing respiratory distress.

Mediators released by neutrophils and macrophages also cause varying degrees of pulmonary vasoconstriction, resulting in pulmonary hypertension. The result of the changes is a ventilation-perfusion mismatch. Although the patient responds with an increased respiratory rate, sufficient oxygen can’t cross the alveolar capillary membrane. Carbon dioxide continues to cross easily and is lost with every exhalation. As oxygen and carbon dioxide levels in the blood decrease, the patient develops increasing tachypnea, hypoxemia, and hypocapnia (low partial pressure of arterial carbon dioxide [PaCO2]).

Pulmonary edema worsens, and hyaline membranes form. Inflammation leads to fibrosis, which further impedes gas exchange. Fibrosis progressively obliterates alveoli, respiratory bronchioles, and the interstitium. Functional residual capacity decreases, and shunting becomes more serious. Hypoxemia leads to metabolic acidosis. At this stage, the patient develops increasing PaCO2, decreasing Ph and partial pressure of arterial oxygen (PaO2), decreasing bicarbonate (HCO3-) levels, and mental confusion.

The end result is respiratory failure. Systematically, neutrophils and inflammatory mediators cause generalized endothelial damage and increased capillary permeability throughout the body. Multiple organ dysfunction syndrome (MODS) occurs as the cascade of mediators affects each system. Death may occur from the influence of ARDS and MODS.


Local inflammatory responses

Summary:

Inflammation is the response of the body's vascularized tissues to harmful stimuli such as infectious agents, mechanical damage, chemical irritants, etc. Inflammation has both local and systemic manifestations and may be either acute or chronic. Local inflammatory response (local inflammation) occurs within the area affected by the harmful stimulus. Acute local inflammation develops within minutes or hours after the influence of a harmful stimulus, has a short duration, and primarily involves the innate immune system. The five classic signs of acute local inflammation are redness, swelling, heat, pain, and loss of function. These classical signs result from the sequence of events that are triggered by tissue damage and allow leukocytes to get to the site of damage to eliminate the causative factor. This sequence involves changes in local hemodynamics and vessel permeability, as well as a complex interaction of leukocytes with endothelium and interstitial tissue through which leukocytes escape the blood vessels. To sustain the vascular changes and attract more immune cells to the site of inflammation, leukocytes and tissue cells secrete a range of inflammatory mediators including interleukins and chemokines. Elimination of the causative factor by leukocytes leads to the resolution of acute inflammation and tissue repair with complete regeneration or scarring. Failure to eliminate the causative agent or prolonged exposure to the causative agent leads to chronic inflammation. It aims to confine the causative agent, may last months to years and primarily involves the adaptive immune system.


Chronic local inflammation:

Chronic local inflammation is due to nondegradable pathogens, prolonged exposure to toxic pathogens, or autoimmune reactions.

Cells involved: mononuclear cells (monocytes, macrophages, lymphocytes, plasma cells), fibroblasts

Leads to necrosis and fibrosis (simultaneous destruction and formation of new tissue)



How Coronavirus Kills: Acute Respiratory Distress Syndrome (ARDS)
 
P

Peatness

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Interesting, I have been taking magnesium taurate recently so this is welcomed, and beginning niacinamide soon. Seems to be a high content of taurine in this supplement and probably won’t be taking it for a too lengthy duration. New to the forum but have seen many of your posts and thank you for your input. Also in Australia so I keep up to date with that psycho-Australia one too. ;)
Thank you and welcome to the forum. That title was intended to draw attention to the region it wasn’t meant to be flippant (perhaps a little bit tongue in cheek). I take what’s happening there very seriously and fear for the safety of everyone who is standing up against medical tyranny and authoritarianism. I didn’t think it would go this far. Each day that passes sees more draconian laws being passed. :welcome
 

Don

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Sep 12, 2020
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Thanks so much for this great post. I dont think you mentioned Oil of Oregano. that might be another good one to use as well
 

Inaut

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EMF Mitigation - Flush Niacin - Big 5 Minerals

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