This study might show that reducing acid production in stomach Luman reduces co2 intracellularly and that co2 protects the mucosal barrier of the stomach. Important to note not extra cellular or in Luman but metabolically and within the cell.
Another thought I had is I have seen studies that disrupted blood flow to the gut will cause damage to mucosa.. Is it possible if tissue concentrations of co2 are lower vasoconstriction and reduced blood flow will occur?
Metabolic base production and mucosal vulnerability during acid inhibition in a mammalian stomach in vitro. - PubMed - NCBI
Another thought I had is I have seen studies that disrupted blood flow to the gut will cause damage to mucosa.. Is it possible if tissue concentrations of co2 are lower vasoconstriction and reduced blood flow will occur?
Metabolic base production and mucosal vulnerability during acid inhibition in a mammalian stomach in vitro. - PubMed - NCBI