• tca300: I understand this is off topic from what you typically teach, but I was wondering if you have run across any information or learned on your own, things that help people grieve over lost loved ones, and or fear of losing others to death? Thank you!

    Ray Peat: It activates the “helplessness” reactions in the body, stress weakening your own life, and I think it can help to get out of that if you think of your life as a continuation of theirs—the same life, though with fewer bodies.

    Rest in Paradise, Raymond Peat  October 12, 1936 - November 24 2022

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Potential Anti-aging Role Of Taurine Via Proper Protein Folding: A Study From Taurine Transporter Kn

paymanz

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Potential Anti-aging Role of Taurine via Proper Protein Folding: A Study from Taurine Transporter Knockout Mouse - Springer

Taurine is effective to several aging-related diseases. Taurine mediates a variety of biological actions, including osmoregulation and protein folding, which may contribute to its anti-aging role. Recent studies have proposed that the decline of protein homeostasis with advancing age leads to several aging-related disorders. Therefore, it is possible that the contribution of taurine to proper protein folding may be associated with the effectiveness against aging-related diseases. Meanwhile, Evidence accumulating from the studies with taurine transporter knockout (TauTKO) mouse has indicated that tissue taurine depletion led to aging-associated disorders in several tissues, including heart, skeletal muscle, liver, skin, and shortened the lifespan. Moreover, muscle taurine depletion causes ER stress to activate unfolded protein response. In conclusion, endogenous taurine acts as an anti-aging molecule via, in part, proper protein folding property.
 

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