Melanin Pigmentation In Mammalian Skin And Its Hormonal Regulation

[Drareg]

This is a comprehensive run through of said topic. It has a category/search bar on the side for specific topics.

Vitamin E ,T3, androgens all discussed.


http://physrev.physiology.org/content/84/4/1155

 

[LeeLemonoil]

Wow, this is an invaluable Ressource, very good work by the authors

 

[golder]

Anyone got any ideas if Melanotan 2 is safe? I've read that it stimulates melanin to darken the skin pigment. Thanks for any input!

 

[Mauritio]

From here:

http://physrev.physiology.org/content/84/4/1155

The semiquinone units are also responsible for eumelanin actions as redox pigment with both reducing and oxidizing capabilities towards oxygen radicals and other chemical redox systems (126, 597, 598).

Additional properties of melanin may include a bactericidal potential via the production of orthoquinones (618),

Taken together, these data imply that melanin is important for skin homeostasis and that tanning itself represents a distress signal.

 

[golder]

From here:

http://physrev.physiology.org/content/84/4/1155

The semiquinone units are also responsible for eumelanin actions as redox pigment with both reducing and oxidizing capabilities towards oxygen radicals and other chemical redox systems (126, 597, 598).

Additional properties of melanin may include a bactericidal potential via the production of orthoquinones (618),

Taken together, these data imply that melanin is important for skin homeostasis and that tanning itself represents a distress signal.

I’m guessing this means to avoid Melanotan 2?

 

[Mauritio]

I’m guessing this means to avoid Melanotan 2?

How do you arrive at that conclusion?

 

[golder]

How do you arrive at that conclusion?

My bad I haven’t given this a thorough read through, I was on the way to work. I picked up on tanning being representative of a stress signal.