Brewer's Yeast A Cure For Diabetes And More..

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“This study suggests that chronic consumption of vitamin A-enriched diet decreases 11β-HSD1 activity in liver and visceral fat of WNIN/Ob obese rats. Decreased 11β-HSD1 activity by vitamin A may result in decreased levels of active glucocorticoids in adipose tissue and possibly contribute to visceral fat loss in these obese rats. Studying the role of various nutrients on the regulation of 11β-HSD1 activity and expression will help in the evolving of dietary approaches to treat obesity and insulin resistance."’


 
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“A 2012 review article published in “Diabetic Medicine” (here) examined 16 studies of Ceylon cinnamon specifically, and uncovered beneficial effects of Ceylon cinnamon for diabetics, yet found no toxicity to the liver and kidneys.

In fact, coumarin-free Ceylon cinnamon may actually be beneficial to the liver, according to studies reviewed by “BMC Complementary and Alternative Medicine”, while showing no negative effects to any other organ systems.

5) Additional Benefits of Ceylon Cinnamon​

Antioxidant​

Ceylon cinnamon also contains antioxidant compounds called proanthocyanidins. Proanthocyanidins are similar to the antioxidant compounds found in green tea and grapes, which have been shown to strengthen capillaries and offer antioxidant protection against heart disease and cancer. It also contains the mineral manganese, which helps the body manage enzymes that produce hormones, repair bones, and works as an antioxidant to protect the body from free radicals.

Insulin Response Improvement​

Cinnamon may also benefit people with insulin resistance or diabetes by improving the body’s natural response to insulin, moderating blood sugar levels, and reducing the risk of hypoglycemia or hyperglycemia incidents.”

 
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This was posted by @charlie in his thread linked below…

“A recent study in the Journal of Agriculture, Food & Chemistry found that coffee had an anti-diabetic effect on mice, improving fatty liver and suppressing hyperglycemia, or high blood sugar. Coffee contains high concentrations of magnesium, antioxidants, niacin (Vitamin B3) and thiamin (Vitamin B1), as well as the beta cells, which may explain why coffee drinkers statistically have less diabetes. Studies on diabetics, actually show the benefits appear to increase with cups of coffee drank.”

 
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“Magnesium plays a role in how our body handles sugar,” Keatley says. “It helps with the action of insulin, the hormone that controls blood sugar levels.” When you have enough magnesium in your body, insulin can work better and your body can manage blood sugar more effectively, Keatley says.”

 
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“Sprouting partially breaks down the starch in the grains, which lowers the carb content (5Trusted Source).

One older study found that sprouted grain bread had the lowest available carbs, with 34 grams (g) in a 4-ounce (oz), or 110-g, serving, compared with 44 g in a 12-grain bread (6Trusted Source).

What’s more, due to its lower carb and higher fiber content, sprouted grain bread had the lowest glycemic index, compared to 11-grain, 12-grain, sourdough, or white bread. Glycemic index is a measure of how quickly a food raises your blood sugar (6Trusted Source).

For this reason, sprouted grain bread is an especially good choice for people living with diabetes or high blood sugar.

In addition, the grains absorb water during the sprouting process, making sprouted grains lower in calories than whole grain flours (6Trusted Source).

Substituting sprouted grain bread for other types of bread may help you lose weight, if that’s a goal for you.”
 
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“Several studies suggest a link between a reduced intake of vitamin K and an increased risk of diabetes. However, the biological mechanisms by which vitamin K protects against diabetes remained a mystery until now. In their study, UdeM associate research professor of medicine Mathieu Ferron and his team at the IRCM were first able to determine that the enzymes involved in gamma-carboxylation and therefore in the use of vitamin K were present in large quantities in pancreatic beta cells, the very cells that produce the precious insulin that controls blood sugar levels. "Diabetes is known to be caused by a reduction in the number of beta cells or by their inability to produce enough insulin, hence our keen interest in this novel finding," said Ferron, a leading researcher in molecular biology. "In order to elucidate the cellular mechanism by which vitamin K maintains beta cell function, it was essential to determine which protein was targeted by gamma-carboxylation in these cells." "We were able to identify a new gamma-carboxylated protein called ERGP," added Julie Lacombe, who conducted the work in Ferron's laboratory. "Our study shows that this protein plays an important role in maintaining physiological levels of calcium in beta cells in order to prevent a disturbance of insulin secretion. Finally, we show that vitamin K through gamma-carboxylation is essential for ERGP to perform its role." This is the first time in 15 years that a novel vitamin K-dependent protein has been identified, opening a new field of research in this area."

 
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“"...A cohort of Canadian adults prescribed statins, and hydrophilic statins, in particular, had higher levels of insulin resistance compared with non-statin users, according to findings published in the Journal of the Endocrine Society. “There is emerging data to suggest that by inhibiting the production of intermediates of cholesterol biosynthesis, statins also inhibit the mevalonate pathway and impede the production of vitamin K2 in peripheral tissues,” Rachel M. Holden, MD, a nephrologist and associate professor in the department of medicine at Queen’s University in Kingston, Ontario, Canada, and colleagues wrote in the study background. There is growing evidence to suggest that vitamin K2 plays a key role in glucose homeostasis as well as vascular calcification. On this background, we hypothesized that statin use would be associated with both insulin resistance and vascular calcification in community-dwelling participants of a large longitudinal study of osteoporosis.””

 
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“Niacinamide, used in moderate doses, can safely help to restrain the excessive production of free fatty acids, and also helps to limit the wasteful conversion of glucose into fat. There is evidence that diabetics are chronically deficient in niacin. Excess fatty acids in the blood probably divert tryptophan from niacin synthesis into serotonin synthesis.” -Ray Peat
 
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“… a new study just found that the Vitamin D in egg yolks might be particularly good for diabetics. People with diabetes often have Vitamin D deficiencies, and the form of Vitamin D in eggs could be particularly beneficial.

Free-range eggs have 3-4 times the Vitamin D of eggs from hens kept indoors.“



“Research has shown that when eggs are baked for 40 minutes, they may lose up to 61% of their vitamin D, compared to up to 18% when they’re fried or boiled for a shorter period of time (11Trusted Source).”

 
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This video that @J.R.K posted elsewhere is really good information as to what happens if we don’t eat enough carbs/sugars, especially for diabetics. One can developed insulin resistance from lack of potassium. The potassium benefit from Ray Peat’s recommended orange juice and milk comes into play here, potatoes too, all are high in potassium…


View: https://youtu.be/xuXIb538Gfs?si=yht7E2ZVPH5hA82v
 
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“Several studies of keto diets have shown that an increased risk of type 2 diabetes does exist early during the diet. In a study by ETH Zurich and University Children's Hospital Zurich, mice were put on one of two different diets - the ketogenic diet or a high fat diet. Metabolic tests showed that abnormal glucose levels and insulin resistance developed in the livers of mice fed a keto diet to a greater extent than in mice fed a high fat diet. As the liver was unable to deal with normal levels of insulin for glucose control, the risk of type 2 diabetes also increased.“

 
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“The ketogenic diet is a high fat diet. When followed 100% the diet requires an individual to consume 50 grams or less of carbohydrates on a daily basis. Often people talk about becoming “fat burners” and having to be on the ketogenic diet long enough to adapt to fat-burning. This is a complete misunderstanding. Humans are not designed to burn fat, except for when there is an emergency. So when we create an environment in which our body has to use a resource to make energy that it would otherwise only use in the case of an emergency, we purposely create an emergency situation in our body.

Emergency situation = chronic exposure to stress hormones. 24 hours. 7 days a week. 365 days a year (if you last on the ketogenic diet that long). The entire purpose of these stress hormones is to increase access to energy for the body. What’s this energy? SUGAR. So, purposely inducing an emergency situation in the body leads to chronically high levels of sugar in the blood. Long-term excess sugar in the blood = insulin resistance. Pre-diabetes. Or even diabetes.

Now, this high fat diet has taken an individual who already has issues with processing carbohydrates farther away from a metabolism that can process carbs well. Not even just poor tolerance of carbohydrates, but full blown insulin resistance. Now, when this individual reintroduces carbohydrates, they will experience immediate weight gain or other side effects of putting excess carbs in a body that doesn’t know how to process them very well.

#2 – The Body Cannot Burn Carbohydrates Well, if There’s Too Much Fat in the Diet​

The name for this concept: the Randle Cycle. In the 1960s, Dr. Randle discovered that there is an inverse relationship between fat and carb burning. Essentially, when there is too much fat in the diet, as is the case for a ketogenic diet or the typical American diet, the body’s ability to burn the carbs we eat goes down. Which means that when we reintroduce carbs after a ketogenic diet, our body doesn’t know how to handle the carbohydrates. It’s pretty similar to a muscle – if you don’t use it, you lose it. A ketogenic diet dramatically reduces the body’s needs to burn carbs, which then stunts its ability to burn carbs when we do eat carbs. Which then leads to a poor tolerance of carbs and insulin resistance. It’s not just the ketogenic diet. Eating too much fat (>25% of your daily calories) also works in the same way.

There you have it. Two reasons why a ketogenic/high-fat diet can lead to insulin resistance, pre-diabetes, or diabetes.”

 
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"Intense exercise damages cells in ways that cumulatively impair metabolism. There is clear evidence that glycolysis, producing lactic acid from glucose, has toxic effects, suppressing respiration and killing cells. Within five minutes, exercise lowers the activity of enzymes that oxidize glucose. Diabetes, Alzheimer's disease, and general aging involve increased lactic acid production and accumulated metabolic (mitochondrial) damage." -Ray Peat
 
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“Additional Sprouted Rice Benefits
Research shows that after germination, brown rice is higher in several antioxidants, vitamin E, protein, healthy fats, and fiber. It also has a lower glycemic index, so it’s better for your blood sugar. Early studies also suggest that sprouted brown rice might have some anti-diabetic properties.”

 
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“People who have liver disease or diabetes should not take vitamin A supplements without their doctor's supervision.

Smokers and people who drink heavy amounts of alcohol should not take beta-carotene supplements.

Both vitamin A and beta-carotene may increase triglycerides, which are fats in the blood. They may even increase the risk of death from heart disease, particularly in smokers.

Vitamin A is found in many different vitamin formulas. Supplements that say "wellness formula," "immune system formula," "cold formula," "eye health formula," "healthy skin formula," or "acne formula," all tend to contain vitamin A. If you take a variety of different formulas, you could be at risk for too much vitamin A.”

https://www.mountsinai.org/health-library/supplement/vitamin-a-retinol#:~:text=People%20who%20have%20liver%20disease,supplements%20without%20their%20doctor's%20supervision.
 
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“Several studies suggest a link between a reduced intake of vitamin K and an increased risk of diabetes. However, the biological mechanisms by which vitamin K protects against diabetes remained a mystery until now. In their study, UdeM associate research professor of medicine Mathieu Ferron and his team at the IRCM were first able to determine that the enzymes involved in gamma-carboxylation and therefore in the use of vitamin K were present in large quantities in pancreatic beta cells, the very cells that produce the precious insulin that controls blood sugar levels.”

 
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“Many people are claiming that fructose consumption has increased greatly in the last 30 or 40 years, and that this is responsible for the epidemic of obesity and diabetes. According to the USDA Economic Research Service, the 2007 calorie consumption as flour and cereal products increased 3% from 1970, while added sugar calories decreased 1%. Calories from meats, eggs, and nuts decreased 4%, from dairy foods decreased 3%, and calories from added fats increased 7%. The percentage of calories from fruits and vegetables stayed the same. The average person consumed 603 calories per day more in 2007 than in 1970. If changes in the national diet are responsible for the increase of obesity, diabetes, and the diseases associated with them, then it would seem that the increased consumption of fat and starch is responsible, and that would be consistent with the known effects of starches and polyunsaturated fats.” -Ray Peat
 
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“When the idea of "glycemic index" was being popularized by dietitians, it was already known that starch, consisting of chains of glucose molecules, had a much higher index than fructose and sucrose. The more rapid appearance of glucose in the blood stimulates more insulin, and insulin stimulates fat synthesis, when there is more glucose than can be oxidized immediately. If starch or glucose is eaten at the same time as polyunsaturated fats, which inhibit its oxidation, it will produce more fat. Many animal experiments show this, even when they are intending to show the dangers of fructose and sucrose.” -Ray Peat
 
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I’ve been eating Marmite every day or so, on sourdough bread. I’m not sure that is it the reason, but i am feeling fantastic since I started this. Maybe it is other factors.
 
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I’ve been eating Marmite every day or so, on sourdough bread. I’m not sure that is it the reason, but i am feeling fantastic since I started this. Maybe it is other factors.
Funny you should say that because I tried again the Vegemite two days ago, and I still am not liking it. The brewers yeast is much easier for me to get down, but I don’t enjoy it either. Nutritional yeast tastes better to me, but like you and I on the collagen, I am unsure about the yeast in nutritional yeast.
 
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