SIBO, GERD, LPR, IBS, & Colitis Could Be Vitamin B3 Deficiency - "Niacin Treats Digestive Problems"

[charlie]

Look what "utilaman" says about Chrohns/Proctitis:

You have Chron's ?

You need to buy Magnesium tablets 250mg and take at least 3 per day....One after each meal and when you start going diahrea just cut back down to 2 or 1 tablet per day. Next add Niacin and fish pills and WALK because walking, niacin, and magnesium have cured my Proctitis. And Proctitis is the same as Chrons in the rectal area..

Magnesium and Niacin are like wonder drugs when it comes to IBD. Just give them 6 months and a year to really start enjoying life again.

Check this from Merck on Niacin DEFICIENCY and GI tract in Chrons and UC I guess.....
,,,,,,,,,,,,,
Niacin - Nutritional Disorders - Merck Manuals Professional Edition
GI symptoms early in the deficiency include burning in the pharynx and esophagus and abdominal discomfort and distention. Constipation is common. Later, nausea, vomiting, and diarrhea may occur. Diarrhea is often bloody because of bowel hyperemia and ulceration.

Source(he is the second reply down):
Having had a bowel movement in over a week? - Crohn's Disease / Ulcerative Colitis - MedHelp

So utilaman and the other article posted above are in agreement that it can take 6 months to turn this deficiency around. Which makes sense because it took a long time to get in this deficient predicament. Although I think some will see results much sooner.

 

[ilhanxx]

good thread, but i used no flush version 500 mg for 3 month, nothing happened, a little good for my anger.

 

[charlie]

good thread, but i used no flush version 500 mg for 3 month, nothing happened, a little good for my anger.

Did you use niacinamide? Also I think all the B vitamins work together so making sure to hit them all along with their co-factors would be prudent. Zinc and B6 status come into play also:
Interaction among niacin, vitamin B6 and zinc in rats receiving ethanol. - PubMed - NCBI

And here is another article I just found about "Dementia" might actually be Pellagra.

Dementia Or Pellagra? Niacin Deficiency In The 21st Century

 

[Astolfo]

@charlie

It's an irrelevant question, but is it worth taking a B complex containing titanium dioxide. It's the only product I could found with a good amount of vit B's and a reasonable price.

Also does it matter to take niacinamide instead of niacin? Which form is the more powerful for dementia or IBS?

 

[ilhanxx]

Did you use niacinamide? Also I think all the B vitamins work together so making sure to hit them all along with their co-factors would be prudent. Zinc and B6 status come into play also:
Interaction among niacin, vitamin B6 and zinc in rats receiving ethanol. - PubMed - NCBI

And here is another article I just found about "Dementia" might actually be Pellagra.

Dementia Or Pellagra? Niacin Deficiency In The 21st Century

I used niacinamide version before. for b complex i drink bewers yeast water about 1 month. tastes awful but It feels good (stress, sleep, skin quality vs.) . I didnt see any difference digestive tracks. Maybe peaty diet enough for me. then It increased belly fat (bewers yeast) . I stopped. when i take b vitamins, i gain weight.

 

[ecstatichamster]

Thank you for this!!!

So my theory is that SIBO, LPR, IBS, UCC and all the other alphabet letter digestive malfunction names are nothing more than vitamin B deficiencies. Although the co-factors will of course need to be with them, and like Amazoniac et el has said, the vitamins run as a constellation.

According to my theory "SIBO-C" aka constipation SIBO is Beriberi. Due to the work of Amazoniac et el 2027(a man ahead of his time) I picked up on that thiamine deficiency(Beriberi) always presented with constipation as the norm. Then you get all other kind of wonderful deficiency symptoms along with it that people report all over the SIBO forums.

So then "SIBO-D" which is SIBO diarrhea would be Pellagra. One of the big symptoms that people report on the SIBO forums is "brain fog". Well, dementia is one of the four D's of Pellagra, dermatitis, diarrhea, dementia, and the final D, death.

So yeh that is my theory I am kicking around right now. When I started researching my theory and found someone else who figured out that Celiac "disease" might actually be Pellagra, and that Ulcerative Colitis was reversed with Niacin. That showed me I was on the right track and this should probably be investigated more thoroughly.

It’s easy to test and downsides minimal. Thank you.

 

[gaze]

Thank you for this!!!

So my theory is that SIBO, LPR, IBS, UCC and all the other alphabet letter digestive malfunction names are nothing more than vitamin B deficiencies. Although the co-factors will of course need to be with them, and like Amazoniac et el has said, the vitamins run as a constellation.

According to my theory "SIBO-C" aka constipation SIBO is Beriberi. Due to the work of Amazoniac et el 2027(a man ahead of his time) I picked up on that thiamine deficiency(Beriberi) always presented with constipation as the norm. Then you get all other kind of wonderful deficiency symptoms along with it that people report all over the SIBO forums.

So then "SIBO-D" which is SIBO diarrhea would be Pellagra. One of the big symptoms that people report on the SIBO forums is "brain fog". Well, dementia is one of the four D's of Pellagra, dermatitis, diarrhea, dementia, and the final D, death.

So yeh that is my theory I am kicking around right now. When I started researching my theory and found someone else who figured out that Celiac "disease" might actually be Pellagra, and that Ulcerative Colitis was reversed with Niacin. That showed me I was on the right track and this should probably be investigated more thoroughly.

Charlie, do you think in trying to cure beri beri, that one should avoid high doses of b6 so it doesn’t interfere? I know some Bs can take over when deficient in others but I havnt seen anything regarding deficiency recovery and how Bs interact with one another

 

[gaze]

I used niacinamide version before. for b complex i drink bewers yeast water about 1 month. tastes awful but It feels good (stress, sleep, skin quality vs.) . I didnt see any difference digestive tracks. Maybe peaty diet enough for me. then It increased belly fat (bewers yeast) . I stopped. when i take b vitamins, i gain weight.

You should consider nutritional yeast. it’s nearly the exact same thing but the yeast is deactivated and isn’t hoppy like brewers yeast(I think)

 

[charlie]

It's an irrelevant question, but is it worth taking a B complex containing titanium dioxide.

I personally would not if I could help it. Titanium dioxide can be a neuro-toxin if I remember correctly.

Also does it matter to take niacinamide instead of niacin? Which form is the more powerful for dementia or IBS?

Ray Peat suggest niacinamide. However, Gerson used nicotinic acid. @Amazoniac is our local nutrient specialist and can maybe weigh in.

Charlie, do you think in trying to cure beri beri, that one should avoid high doses of b6 so it doesn’t interfere? I know some Bs can take over when deficient in others but I havnt seen anything regarding deficiency recovery and how Bs interact with one another

I honestly do not know.

 

[Amazoniac]

@charlie

It's an irrelevant question, but is it worth taking a B complex containing titanium dioxide. It's the only product I could found with a good amount of vit B's and a reasonable price.

Also does it matter to take niacinamide instead of niacin? Which form is the more powerful for dementia or IBS?

I doubt that it beats the price of buying them in bulk if you compare similar amounts, they will last you a long time and you can adjust according to your needs. The amount should be small and there could be a greater exposure from unsuspected sources; I would avoid ingesting it, but even applying topically is questionable in spite of people lathering their skins with it as sunnyscreen.

- A pilot study on the percutaneous absorption of microfine titanium dioxide from sunscreens

- Titanium Dioxide as Food Additive (they touch on particle size)
- The food additive E171 and titanium dioxide nanoparticles indirectly alter the homeostasis of human intestinal epithelial cells in vitro

- Particles March 2019 Excellent

A company that still has these in their products is probably one that doesn't care about the quality of the active ingredients anyway, so it's likely not the only problem in the formula.

Join with 2 friends, and with $50 or so divided between you, there will be enough B-vitamins to last you an entire deciphering of Terma's acronyms.

Regarding niacin, both are safe, the concerns that people usually have with nicotinic acid also apply to nicotinamide, so if you're using human doses that don't induce flushing (without adaptation), it shouldn't make much difference.

 

[thirdcatgy]

I've also be curious about B-Vits and Magnesium, etc. which SIBO depletes causing a vicious cycle. Interesting about the duration to heal mucousal.

With the gut/intestinal damage, might it might more advantageous to get the vitamins via injection for a period?

 

[charlie]

Ran across this today. The co-factors are important!!!

Abstract
A patient with Crohn's disease and long-standing diarrhea resulting in a combined thiamine and magnesium deficiency is presented. Despite massive doses of thiamine i.v., the symptoms of thiamine deficiency could not be suppressed until the magnesium deficiency was corrected as well. This case report emphasizes the dependence of thiamine on magnesium for an adequate function in the body.

Aggravation of thiamine deficiency by magnesium depletion. A case report. - PubMed - NCBI

 

[Cirion]

I'm taking epsom salt baths virtually every night now myself for the magnesium (and relaxation).

 

[MetabolicTrash]

Any idea or people who may have seen help with hiatal hernias due to high/higher niacin/niacinamide dosing?

I know it is more regarded as a "mechanical issue" but I think some people have noted certain supplements or such has helped it subside at least.

I ask because this pertains to the gut/is an issue related to the subjects mentioned.

 

[Inaut]

fyi i've switched from gelatin to hydrolyzed collagen (3 tbsps a day) and my gut feels much better. Gelatin was tough to tolerate as I didnt always do a good job dissolving it.

 

[MetabolicTrash]

I'm going to switch to hydrolyzed collagen at some point too.

Also -- back at the main topic -- is there to be any benefit from supplementing with niacin/niacinamide for digestive/gut issues when thyroid may still be poor? My understanding is that the thyroid is like a master regulator of all this stuff. What would happen if one made a combined cocktail of vitamins/etc. to try and help with digestive issues head on, but did not address the actual underlying thyroid issue first? Would this be more harmful or just be more like a temporary patch that can work so long as the supplementation is constant, even despite the poor thyroid? Would be interesting to know how this might work (fixing "sub-processes" rather than main ones).

 

[Bart1]

I'm coming back to this as well. Antibiotics, phages etc. It helps a bit, but still the bloating remains. I think for me it's probably a sort of congested liver because the liver cannot properly do it's functions because of deficiencies, especially in the B department. Probably also a fatty liver from the sugar that is not properly metabolised.

Doesn't sucrose require more B vitamins ?

What kind of protocol do you guys suggest ? I take a dosage of B complex but feel I do very good on additional Thiamine and Niacinamide and maybe Riboflavin. I noticed I have nail clubbing and with multiple dosages through the day of thiamin and niacinamide my nails start to straighten more. I notice when I take niacin with fruit juice I start to get more CO2.

Does a lot of coffee deplete b vitamins ? I read somewhere it might deplete B6?

 

[Jem Oz]

Bump. Anyone have any updates on this/these topics? Anyone know what a good 6 month niacinamide protocol would be? (500 mg spread through the day?). If adding magnesium, any ideas on dose?

 

[Tarmander]

@charlie

Did you ever collect more anecdotal evidence on B3 for these alphabet digestive diseases?

 

[mbachiu]

Any idea or people who may have seen help with hiatal hernias due to high/higher niacin/niacinamide dosing?

I know it is more regarded as a "mechanical issue" but I think some people have noted certain supplements or such has helped it subside at least.

I ask because this pertains to the gut/is an issue related to the subjects mentioned.

Just seeing this. I have a hiatal hernia. I have been experimenting with high dose B vitamins (including methylated b vitamins, which aren’t Peaty, I know). Hiatal hernia has been 90% over the last month