vitamin b3

Another study sent to me by the Austrian collaborator. Once again, the energetic origin of "incurable" diseases like amyotrophic lateral sclerosis (ALS) is on full display. The study elucidates that ALL types of ALS are characterized by metabolic/energetic abnormalities and the metabolic...

A very interesting study, sent to me by a collaborator who lives in Austria. It demonstrated that depression is accompanied by increased SIRT1 activity (i.e. increased fatty acid oxidation), lower ATP levels and redox balance shifted towards reduction. The study demonstrated that animals without...

"Results of the trial, led by Professor Jonathan Crowston and Dr. Flora Hui at the Center for Eye Research Australia, are published today in Clinical and Experimental Ophthalmology. They show "significant improvement" in the visual function of glaucoma patients who received a daily high dose of...

The title of the post sounds a bit too good to be true but this is basically what the case study claims and is also reported by the mouthpiece of Big Pharma - the Science Magazine. So, little by little the truth comes out, which is always good news. The only bad news in this case is that the...

Over the last 2-3 years I have seen a dramatic increase in the number of studies and popular press articles using the keywords "controversial", "paradox", "paradigm shift", "ameliorates an incurable condition X", etc. This is just a thinly veiled attempt to mask the collapse of the corrupt dogma...

And also factor in ACE2 and Iron. Lots of peaty points here. Wait a bit until I link and translate.

As many forum users know, brain cancer rates have been steadily rising over the last 3 decades and are now a leading cause of death in both elderly and also very young people. The most common (and deadly) form of brain cancer is glioblastoma multiforme and the average life expectancy after...

A great new study that demonstrated nicotinamide (NAM) may also have anti-fibrotic effects in addition to its positive effects on maintaining favorable NAD/NADH ratio and redox balance. The mechanism of action of NAM was inhibition of the TGF-β pathway and overall reduction of inflammation. This...

A great new study, which once again confirms the importance of metabolism in "aging" disorders such as infertility (both female and male) and menopause. More specifically, it was the increase in NAD/NADH ratio that was the main mechanism of action behind the beneficial effects of nicotinamide...

As many of my readers know, the link between niacinamide and schizophrenia dates back at least the 1950s and possibly much earlier. The late Abram Hoffer, one of the founders of the orthomolecular approach, was convinced that stress was a huge factor in mental illness and ran several successful...

Just over a week ago I posted a thread on ALS being linked to increased fatty acid oxidation (FAO) and as such a decreased glucose availability/oxidation. ALS Tied To Increased Fat Oxidation (FAO), Increasing Glucose May Treat It Now, the study below further corroborates this FAO-disease...

There is an old study often cited by Peat in regards to liver health and estrogen. That study found that vitamins B1 (thiamine) and B2 (riboflavin) are crucial for the deactivation/metabolism of estrogen by the liver. Vitamins B1 & B2 Are Required For Estrogen Inactivation By Liver The study...

This is a human study, so the findings are that much more relevant even though they probably do not come as a surprise to users of this forum. The duration of the study was just 6 weeks and the dose was 500mg nicotinamide riboside (NR) twice a day (for a total of 1,000mg). There were no side...

Neuroblastoma is one of the most common brain cancers and one of the most lethal ones of all cancers. Senator John McCain is probably the most famous recent victims of this cancer, and others famous cases include Senator Ted Kennedy and one of Joe Biden's son. The latter two died from the cancer...

Yet another study on the beneficial effects of raising NAD levels, and unlike other recent studies this one is not sponsored by ChromaDex. This study used nicotinamide mononucleotide (NMN), and human studies have shown that niacinamide is equally effective as NMN in raising NAD levels. Also, as...

The effect of niacinamide on osteoarthritis: A pilot study In the 1940's and 50's William Kaufman treated several hundred patients with both osteo and rheumatoid arthritis with large doses of niacinamide. The researchers here are following Kaufman's approach. They conducted a three month...

I posted a few studies recently on vitamin C and niacinamide as potential cancer treatments. Linus Pauling May Have Been Vindicated - Vitamin C May Treat Cancer Inhibiting Lipolysis May Treat / Cure Cancer This new study corroborates these initial findings. Unfortunately, the study is worded in...

About 2 years ago an Australian study hit frontpage news. It found that ingesting 1g niacinamide daily significantly reduced the risk of non-melanoma skin cancers. Vitamin B3 Prevents And Reverses Skin Cancer Now, a new study and a review found that the same dose of niacinamide may work for...

Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice. - PubMed - NCBI Glaucomas are neurodegenerative diseases that cause vision loss, especially in the elderly. The mechanisms initiating glaucoma and driving neuronal vulnerability during normal aging are...

This study shows that depletion of NAD is a direct cause of the so-called hepatocellular carcinoma (HCC), which is the most common type of liver cancer. People with HCC often develop metastases in the pancreas and in advanced stages, the condition is indistinguishable from pancreatic cancer...