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niacin

  1. aliml

    Niacin receptor agonists may prevent the progression of Alzheimer’s disease

    The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer’s disease Abstract Increased dietary intake of niacin has been correlated with reduced risk of Alzheimer’s disease (AD). Niacin serves as a high-affinity ligand for the receptor...
  2. L

    Problems with Niacinamide

    OK so like a couple weeks ago I have a decided to take niacin again but this time I made sure to take Niacinamide I only took one 500 mg tablet I had a good reaction at first but soon it seem to get worse but not on the same level maybe close too but it was more milder and there were still...
  3. C

    Guy claims high dose Melatonin & Niacin is a cure all and also cures Covid/long Covid and vaccine damage

    I wondered what you guys think about this. Dmitry Kat's who is supposedly an epidemiologist/PHD was recently gaining a lot of attention on twitter promoting his protocol of Niacin and Melatonin to cure Covid and vaccine damage. He's since been banned and is now on telegram. He's kicked me out of...
  4. Mauritio

    Picamilon - a better GABA alternative ?

    Picamilon is a molecular combination of vitamin B3 and GABA , created in russia . It crossed the blood brain barrier and then gets metabolized into B3 and GABA . Thus it was shown to have brain protective , mood enhancing, and lactate lowering effects . It helps to treat parkinsons ,by...
  5. IROM

    Alpecin shampoo: Caffeine, Taurine and Niacinamide (are corporations on to Peating?)

    Just bough this German brand: Alpecin. It contains caffeine, taurine and niacinamide. After a long search for a perfect ready-made shampoo, I may have found it. I was looking in American stores for the longest time and all the caffeine shampoos have garbage like hemp oil or other seed oils...
  6. SOMO

    Niacinamide + Vit C = Niacin?

    Recently I saw an ad for a popular skincare brand called "The Ordinary" which contains 10% Niacinamide. The commercial stated that if you use any sort of Vitamin-C containing product, to use it apart from the Niacinamide cream. That is, several hours apart. Their rationale for this was that...
  7. haidut

    Vitamin B3 May Treat "incurable" Muscle Disease

    Over the last 2-3 years I have seen a dramatic increase in the number of studies and popular press articles using the keywords "controversial", "paradox", "paradigm shift", "ameliorates an incurable condition X", etc. This is just a thinly veiled attempt to mask the collapse of the corrupt dogma...
  8. haidut

    Vitamin B3 Remarkably Therapeutic For Brain Cancer (glioblastoma)

    As many forum users know, brain cancer rates have been steadily rising over the last 3 decades and are now a leading cause of death in both elderly and also very young people. The most common (and deadly) form of brain cancer is glioblastoma multiforme and the average life expectancy after...
  9. haidut

    Dietary Niacinamide (B3) Deficiency May Be A Cause Of Schizophrenia

    As many of my readers know, the link between niacinamide and schizophrenia dates back at least the 1950s and possibly much earlier. The late Abram Hoffer, one of the founders of the orthomolecular approach, was convinced that stress was a huge factor in mental illness and ran several successful...
  10. charlie

    Niacin - Intestinal Permeability And Oxidative Stress In Patients With Alcoholic Pellagra

    CONCLUSIONS: The results suggest that niacin and vitamin E deficiency in patients with pellagra could be important factors in increased intestinal permeability and decreased antioxidant conditions, recovering to normal values after treatment with niacin, associated to alcohol abstinence and a...
  11. redsun

    Testimonial For Niacin - It Just Works

    Per the title, this is just my personal successful experience with using niacin that I wanted to share. Usually I don't care to make posts like this, but seeing as there are just too many members here running around aimlessly playing with foods, food timings, avoiding nutritious foods like...
  12. charlie

    SIBO, GERD, LPR, IBS, & Colitis Could Be Vitamin B3 Deficiency - "Niacin Treats Digestive Problems"

    "Many digestive problems such as bloating, abdominal distention or pain, heartburn and belching are caused by a lack of stomach acid (hypochlorhydria) which can be traced to a lack of niacin. An adequate output of stomach acid is required in order to prevent fungal and bacterial overgrowth in...
  13. Travis

    On Pellagra

    Pellagra is fairly well understood, but there is still some persistent mythology surrounding the etiology. Everyone knows that niacin is the characteristic deficiency, but few are aware of the central importance that leucine plays in this. The somewhat low tryptophan and niacin content of corn...
  14. haidut

    More Than One Third Of Men And Almost Half Of Women Are Energy Deficient

    I wanted to note from the start that this is NOT about calories, this is about ENERGY deficiency as a result of bad metabolism. So, while not the same as hypothyroidism, this study shows just how sick the general population is (if we assume that energetic deficiency is behind all diseases). Now...
  15. P

    Vitamin B3/NAD Fully Prevents The Development Of Glaucoma In Mice And Halts Its Progression If Alrea

    Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice | Science "Oral administration of the NAD+ precursor nicotinamide (vitamin B3), and/or gene therapy (driving expression of Nmnat1, a key NAD+-producing enzyme), was protective both prophylactically and as an...
  16. haidut

    Cancer Addiction To Fat Confirmed; Niacinamide As Possible Treatment

    This is the latest of a number of studies over the last year or so that point the finger at fat (and not sugar) as the primary factor in tumor growth. I posted a few studies in the past showing that tumor cells are highly dependent on fat for growth and proliferation, and a number of...
  17. P

    Prolonged Niacin Treatment Leads To Increased Adipose Tissue Polyunsaturated Fatty Acid Synthesis

    This regards niacin. I don't know if would also apply to niacinamide, hence posting it here to get opinions. http://www.jlr.org/content/early/2014/10/15/jlr.M051938.full.pdf
  18. haidut

    Positive Impact Of Vitamin B3 On CVD Is Not Due To Lowering Cholesterol

    Comparisons with treatment with niacin to raise HDL and lower LDL has been considered the gold-standard for all new statin drugs. However, it has been shown that both niacin and niacinamide have the same protective effects on cardiovascular disease (CVD) despite the fact that niacinamide has...
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