niacinamide

I wondered what you guys think about this. Dmitry Kat's who is supposedly an epidemiologist/PHD was recently gaining a lot of attention on twitter promoting his protocol of Niacin and Melatonin to cure Covid and vaccine damage. He's since been banned and is now on telegram. He's kicked me out of...

There has been a steady increase in human studies with vitamin B3 analogs over the last 3-5 years. Most of that human research is sponsored by the company ChromaDex, which sells a proprietary formulation of nicotinamide riboside (NR), despite its own studies demonstrating that niacinamide /...

I would like to ask for your opinion on some skin care products as I am not yet fully aware of the harmful ingredients from Ray Peat's point of view and I am trying to review a line of products that I am familiar with. Thanks in advance. The first is a tranexamic acid cream: > Aqua (Water)...

Endotoxin can significantly negatively affect your health, from chronic low-grade inflammation, joint degeneration, organ inflammation and dysfunction, brain degeneration, insulin resistance, etc. Most people know that gut dysbiosis can increase endotoxin production and absorption into the body...

Hello all. My mother has borderline diabetes. Have heard that niacinamide can help lower blood sugar. Does anybody have any sources or experience indicating what dosages she should try for desired effect? I am also having her try using fructose as well as getting ketamine treatment since Peat...

This is about a family member. She is 56yo. This morning she was diagnosed with head cancer... doctors gave her a short term to live. They want to put her on chemotherapy. What can i do for her ? Is there any way possible to reverse this ? @haidut @mrchibbs @Tarmander

A very interesting study, which demonstrates the unique synergy between glucose and vitamin B3 in treating deficiencies of function in Complex I & II of the electron transport chain (ETC). Deficiencies on those metabolic steps are the most common causes for the wide varieties of debilitating...

About a year ago, a publication came out that demonstrated therapeutic effects of raising the (mitochondrial) NAD/NADH ratio in glaucoma patients. That study used niacinamide (NAM) and suggested that the "irreversible" changes in eye structure seen in glaucoma patients are in fact nothing more...

Another study sent to me by the Austrian collaborator. Once again, the energetic origin of "incurable" diseases like amyotrophic lateral sclerosis (ALS) is on full display. The study elucidates that ALL types of ALS are characterized by metabolic/energetic abnormalities and the metabolic...

Hello ,for the past year i ate a peat inspired diet with sometimes pufa cheats, pretty high calorie i gained some weight (muscle and fat) and a 2 weeks ago i decided to do a pufa deplition to lose some weight. I'm eating 0 fat from skim milk,bananas, homemade beetroot juice ,orange juice and...

Can I break open a Niacinamide 500mg capsule and use about 100mg in water? Same question for Pregnenolone 10mg and use 5mg in water? The reason I'm asking this "Duh" question is because I did it a couple of times already and felt bitterness and a sting when I poured the powders on my tongue and...

An exploratory LC‐MS‐based metabolomics study reveals differences in aqueous humor composition between diabetic and non‐diabetic patients with cataract - PubAg An exploratory LC‐MS‐based metabolomics study reveals differences in aqueous humor composition between diabetic and non‐diabetic...

"Results of the trial, led by Professor Jonathan Crowston and Dr. Flora Hui at the Center for Eye Research Australia, are published today in Clinical and Experimental Ophthalmology. They show "significant improvement" in the visual function of glaucoma patients who received a daily high dose of...

The title of the post sounds a bit too good to be true but this is basically what the case study claims and is also reported by the mouthpiece of Big Pharma - the Science Magazine. So, little by little the truth comes out, which is always good news. The only bad news in this case is that the...

Over the last 2-3 years I have seen a dramatic increase in the number of studies and popular press articles using the keywords "controversial", "paradox", "paradigm shift", "ameliorates an incurable condition X", etc. This is just a thinly veiled attempt to mask the collapse of the corrupt dogma...

A rather timely study, which demonstrates once again the crucial role energy plays even in "non-metabolic" diseases such as viral infections. At this point, even mainstream medicine admits that every function of the organism requires energy, so it would be plausible to expect an organism with...

As many forum users know, brain cancer rates have been steadily rising over the last 3 decades and are now a leading cause of death in both elderly and also very young people. The most common (and deadly) form of brain cancer is glioblastoma multiforme and the average life expectancy after...

A great new study that demonstrated nicotinamide (NAM) may also have anti-fibrotic effects in addition to its positive effects on maintaining favorable NAD/NADH ratio and redox balance. The mechanism of action of NAM was inhibition of the TGF-β pathway and overall reduction of inflammation. This...

One of the blockbuster studies I have seen over the last 12 months. It reads as if written by Peat himself and discusses tissue regeneration, Randle cycle, dietary control of metabolism, etc. AFAIK this is the first study brave enough to demonstrate that simply switching fuel types in an...

A great new study, which once again confirms the importance of metabolism in "aging" disorders such as infertility (both female and male) and menopause. More specifically, it was the increase in NAD/NADH ratio that was the main mechanism of action behind the beneficial effects of nicotinamide...