niacinamide

  1. haidut

    Glucose + vitamin B3 combo synergistic for treating mitochondrial disease

    A very interesting study, which demonstrates the unique synergy between glucose and vitamin B3 in treating deficiencies of function in Complex I & II of the electron transport chain (ETC). Deficiencies on those metabolic steps are the most common causes for the wide varieties of debilitating...
  2. haidut

    Glaucoma likely a metabolic disease, treatable by pyruvate and/or niacinamide

    About a year ago, a publication came out that demonstrated therapeutic effects of raising the (mitochondrial) NAD/NADH ratio in glaucoma patients. That study used niacinamide (NAM) and suggested that the "irreversible" changes in eye structure seen in glaucoma patients are in fact nothing more...
  3. haidut

    Niacinamide may treat ALS by improving energetic state

    Another study sent to me by the Austrian collaborator. Once again, the energetic origin of "incurable" diseases like amyotrophic lateral sclerosis (ALS) is on full display. The study elucidates that ALL types of ALS are characterized by metabolic/energetic abnormalities and the metabolic...
  4. Razvan

    Pufa Deplition Is Amazing

    Hello ,for the past year i ate a peat inspired diet with sometimes pufa cheats, pretty high calorie i gained some weight (muscle and fat) and a 2 weeks ago i decided to do a pufa deplition to lose some weight. I'm eating 0 fat from skim milk,bananas, homemade beetroot juice ,orange juice and...
  5. pauljacob

    Can I Break Open A Niacinamide, Pregnenolone Capsule?

    Can I break open a Niacinamide 500mg capsule and use about 100mg in water? Same question for Pregnenolone 10mg and use 5mg in water? The reason I'm asking this "Duh" question is because I did it a couple of times already and felt bitterness and a sting when I poured the powders on my tongue and...
  6. Tristan Loscha

    Metabolomics Study Reveals Differences Between Diabetic And Non‐diabetic Patients With Cataract

    An exploratory LC‐MS‐based metabolomics study reveals differences in aqueous humor composition between diabetic and non‐diabetic patients with cataract - PubAg An exploratory LC‐MS‐based metabolomics study reveals differences in aqueous humor composition between diabetic and non‐diabetic...
  7. charlie

    Vitamin B3 (Niacinamide) Shows Promise For Glaucoma Patients In Clinical Trial

    "Results of the trial, led by Professor Jonathan Crowston and Dr. Flora Hui at the Center for Eye Research Australia, are published today in Clinical and Experimental Ophthalmology. They show "significant improvement" in the visual function of glaucoma patients who received a daily high dose of...
  8. haidut

    Niacinamide (vitamin B3) May Cure HIV (human Study)

    The title of the post sounds a bit too good to be true but this is basically what the case study claims and is also reported by the mouthpiece of Big Pharma - the Science Magazine. So, little by little the truth comes out, which is always good news. The only bad news in this case is that the...
  9. haidut

    Vitamin B3 May Treat "incurable" Muscle Disease

    Over the last 2-3 years I have seen a dramatic increase in the number of studies and popular press articles using the keywords "controversial", "paradox", "paradigm shift", "ameliorates an incurable condition X", etc. This is just a thinly veiled attempt to mask the collapse of the corrupt dogma...
  10. haidut

    Raising NAD Levels May Be Therapeutic For COVID-19

    A rather timely study, which demonstrates once again the crucial role energy plays even in "non-metabolic" diseases such as viral infections. At this point, even mainstream medicine admits that every function of the organism requires energy, so it would be plausible to expect an organism with...
  11. haidut

    Vitamin B3 Remarkably Therapeutic For Brain Cancer (glioblastoma)

    As many forum users know, brain cancer rates have been steadily rising over the last 3 decades and are now a leading cause of death in both elderly and also very young people. The most common (and deadly) form of brain cancer is glioblastoma multiforme and the average life expectancy after...
  12. haidut

    Niacinamide May Treat Fibrotic Eye Disease And Prevent Vision Loss

    A great new study that demonstrated nicotinamide (NAM) may also have anti-fibrotic effects in addition to its positive effects on maintaining favorable NAD/NADH ratio and redox balance. The mechanism of action of NAM was inhibition of the TGF-β pathway and overall reduction of inflammation. This...
  13. haidut

    Forcing The Heart To Burn Glucose Instead Of Fat May Cure Heart Failure

    One of the blockbuster studies I have seen over the last 12 months. It reads as if written by Peat himself and discusses tissue regeneration, Randle cycle, dietary control of metabolism, etc. AFAIK this is the first study brave enough to demonstrate that simply switching fuel types in an...
  14. haidut

    Low-dose (but Not High) Niacinamide Reverses Reproductive Decline In Old Females

    A great new study, which once again confirms the importance of metabolism in "aging" disorders such as infertility (both female and male) and menopause. More specifically, it was the increase in NAD/NADH ratio that was the main mechanism of action behind the beneficial effects of nicotinamide...
  15. G

    Niacinamide Long Term Use

    Good afternoon everyone. Just a small question about Niacinamide. I've been using Niacinamide 150 mg daily, 50mg at breakfast, 50mg at lunch and 50mg dinner. Is this the recommended daily dosage for long term use ? Is safe to use Niacinamide long term ? Thank you so much. G.C
  16. haidut

    Dietary Niacinamide (B3) Deficiency May Be A Cause Of Schizophrenia

    As many of my readers know, the link between niacinamide and schizophrenia dates back at least the 1950s and possibly much earlier. The late Abram Hoffer, one of the founders of the orthomolecular approach, was convinced that stress was a huge factor in mental illness and ran several successful...
  17. haidut

    Acidosis (Warburg Effect) Drives Cancer Through Increased Fat Oxidation (Randle Cycle)

    The evidence continues to pile on that naming the (in)famous observation made by Otto Warburg in regards to cancer an "effect" is one of the most profound falsehoods the medical profession has ever concocted. Almost a century after the Warburg "Effect" term was coined, the evidence rapidly...
  18. haidut

    Niacinamide May Restore Female Fertility In Old Age

    The mainstream medical dogma is that after the onset of menopause, female reproductive potential is essentially zero. I posted a thread recently that challenged that dogma and demonstrated that infertility is essentially an energetic dysfunction process and can be reversed with exposure to red...
  19. haidut

    Niacinamide May Improve Symptoms Of ALS

    Just over a week ago I posted a thread on ALS being linked to increased fatty acid oxidation (FAO) and as such a decreased glucose availability/oxidation. ALS Tied To Increased Fat Oxidation (FAO), Increasing Glucose May Treat It Now, the study below further corroborates this FAO-disease...
  20. haidut

    Fibromyalgia May Be Simply A Sign Of Insulin Resistance

    As many of your have seen on TV, there is currently a boom in ads for drigs to treat fibromyalgia. This condition is yet another one of mysterious origins, at least according to mainstream medicine. The treatment consists mainly of GABA agonists like Lyrica but the official version is (of...
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