Why Does Abilify Lower Prolactin

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why does abilify lower prolactin is it a good drug

Aripiprazole and Prolactin Study - Full Text View - ClinicalTrials.gov

 

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Adding aripiprazole can reduce stubborn prolactin​

Unlike most antipsychotics, which have antagonistic activity at the dopamine-2 receptors, aripiprazole (Abilify) is a dopamine receptor agonist. As such, it does not have the same dopamine-blocking effect – which allows dopamine to continue regulating prolactin production in the pituitary gland, Dr. Carlson said at a psychopharmacology update held by the American Academy of Child and Adolescent Psychiatry.

"This gives it the ability to actually lower prolactin, which is something we can use therapeutically," said Dr. Carlson, chief of the division of endocrinology at Stony Brook (N.Y.) University.