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- Aug 24, 2017
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I thought I saw someone on the Solban thread say it's around there, but upon further investigation, it's much lower.Do you have a study that shows 20-30% absorption ?
I saw a study showing 10-15%
"The bioavailability of cutaneous aspirin was 4%-8% that of oral aspirin. Cutaneous aspirin (750 mg/day for 10 days) significantly lowered serum thromboxane (by 85%) and gastric and duodenal prostaglandins (by 49%-71%); placebo had no effect. Moreover, cutaneous aspirin, but not placebo, resulted in significant gastric mucosal injury. These findings demonstrate that even tiny amounts of aspirin in the blood (2 microM) have inhibitory effects on prostaglandin production in the human stomach and duodenum that result in gastric mucosal damage, even without direct exposure of the stomach to aspirin." (R)
This one found higher absorption: "The percutaneous absorption of salicylic acid is normally 60% with intact skin" (R)