Electrisio
Member
- Joined
- Feb 25, 2017
- Messages
- 73
I've done posts before on symptoms of heart pounding and bounding pulse that I can't get rid of. I've had all the cardiac tests which show nothing is drastically wrong, except perhaps that my left ventricle is relatively large and my blood volumes are high, especially my stroke volume. My heart rate is low, around 45-50 and my blood pressure is lowish at 100/60. My cardiologist suggests that I need to get my heart rate up in order to reduce stroke volume. The high stroke volume is in theory what is causing my excessively strong pulse. There aren't really any medications that can help me that much. I tried beta blockers but they actually made the problem worse, which I believe is due to the slowing of the heart and increased stoke volume. The problem is unusual so I am having to think out of the box in terms of things to try as I've exhausted the normal avenues. I came across some studies showing that famotidine may be able to achieve the effects of what I am looking for:
Anyone had experience with it or perhaps know anything else that could exert the effect I am looking for?
Negative effects of famotidine on cardiac performance assessed by noninvasive hemodynamic measurements - PubMed
In a randomized placebo-controlled study 12 healthy volunteers were treated for 1 wk each with 10 mg of nifedipine four times daily plus placebo or the same dose of nifedipine concurrently with 40 mg of famotidine once a day. Famotidine did not significantly alter pharmacokinetic parameters of...
pubmed.ncbi.nlm.nih.gov
Hemodynamic effects of quinidine and famotidine in patients with congestive heart failure - PubMed
In a randomized, placebo-controlled, double-blind study, 12 patients with congestive heart failure (New York Heart Association class II) were successively treated for 1 week each with placebo, 40 mg famotidine, and 1000 mg quinidine. On the seventh treatment day, heart rate, blood pressure...
pubmed.ncbi.nlm.nih.gov
Changes in the effects of nizatidine and famotidine on cardiac performance after pretreatment with ranitidine - European Journal of Clinical Pharmacology
This was an open, randomized study of the cardiovascular effects of the histamine H2 receptor antagonists ranitidine, famotidine, and nizatidine after single oral doses alone or in combination in healthy volunteers.When compared with placebo ranitidine (450 mg) did not have any haemodynamic...
link.springer.com
Anyone had experience with it or perhaps know anything else that could exert the effect I am looking for?