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"Many scientists doing microbiome experiments with mice use antibiotics to clear out bacteria before their intervention," says Amir Zarrinpar, an assistant professor at UC San Diego and the paper's first author. "We show that such clearing out has a tremendous effect on the metabolism of the mouse. So some metabolic effects can be attributed to this depletion rather than the intervention."
https://www.sciencedaily.com/releases/2018/07/180723155722.htm
Study in mice finds microbiome-induced changes in liver may influence diabetes
A new study from the Salk Institute has found that mice that have their microbiomes depleted with antibiotics have decreased levels of glucose in their blood and better insulin sensitivity. The research has implications for understanding the role of the microbiome in diabetes. It also could lead to better insight into the side effects seen in people who are being treated with high levels of antibiotics. The study appeared in the journal Nature Communications on July 20, 2018.
https://www.sciencedaily.com/releases/2018/07/180723155722.htm
Study in mice finds microbiome-induced changes in liver may influence diabetes
A new study from the Salk Institute has found that mice that have their microbiomes depleted with antibiotics have decreased levels of glucose in their blood and better insulin sensitivity. The research has implications for understanding the role of the microbiome in diabetes. It also could lead to better insight into the side effects seen in people who are being treated with high levels of antibiotics. The study appeared in the journal Nature Communications on July 20, 2018.