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Some resources about betaine.
Betaine in Inflammation: Mechanistic Aspects and Applications
Betaine is known as trimethylglycine and is widely distributed in animals, plants, and microorganisms. Betaine is known to function physiologically as an important osmoprotectant and methyl group donor. Accumulating evidence has shown that betaine has ...www.ncbi.nlm.nih.govBetaine is a positive regulator of mitochondrial respiration - PubMed
Betaine protects cells from environmental stress and serves as a methyl donor in several biochemical pathways. It reduces cardiovascular disease risk and protects liver cells from alcoholic liver damage and nonalcoholic steatohepatitis. Its pretreatment can rescue cells exposed to toxins such as...pubmed.ncbi.nlm.nih.govBetaine enhances the cellular survival via mitochondrial fusion and fission factors, MFN2 and DRP1
Betaine is a key metabolite of the methionine cycle and known for attenuating alcoholic steatosis in the liver. Recent studies have focused on the protection effect of betaine in mitochondrial regulation through the enhanced oxidative phosphorylation ...www.ncbi.nlm.nih.govBetaine attenuates LPS-induced downregulation of Occludin and Claudin-1 and restores intestinal barrier function - BMC Veterinary Research
Background The intestinal epithelial barrier, which works as the first line of defense between the luminal environment and the host, once destroyed, it will cause serious inflammation or other intestinal diseases. Tight junctions (TJs) play a vital role to maintain the integrity of the...bmcvetres.biomedcentral.comThe effects of 14-week betaine supplementation on endocrine markers, body composition and anthropometrics in professional youth soccer players: a double blind, randomized, placebo-controlled trial - Journal of the International Society of Sports Nutr
Objective Betaine supplementation may enhance body composition outcomes when supplemented chronically during an exercise program. The purpose of this study was to evaluate the effect of betaine supplementation on development-related hormones, body composition, and anthropometrics in professional...jissn.biomedcentral.comDietary Betaine Addition Promotes Hepatic Cholesterol Synthesis, Bile Acid Conversion, and Export in Rats
It is widely reported how betaine addition regulates lipid metabolism but how betaine affects cholesterol metabolism is still unknown. This study aimed to investigate the role of betaine in hepatic cholesterol metabolism of Sprague-Dawley rats. Rats were ...www.ncbi.nlm.nih.govBetaine treatment protects liver through regulating mitochondrial function and counteracting oxidative stress in acute and chronic animal models of hepatic injury - PubMed
Betaine is a derivative of the amino acid glycine widely investigated for its hepatoprotective properties against alcoholism. The protective properties of betaine in different other experimental models also have been documented. On the other hand, the exact cellular mechanism of cytoprotection...pubmed.ncbi.nlm.nih.govBetaine supplementation enhances anabolic endocrine and Akt signaling in response to acute bouts of exercise - PubMed
Our aim was to examine the effect of betaine supplementation on selected circulating hormonal measures and Akt muscle signaling proteins after an acute exercise session. Twelve trained men (age 19.7 ± 1.23 years) underwent 2 weeks of supplementation with either betaine (B) (1.25 g BID) or...pubmed.ncbi.nlm.nih.govLow dose betaine supplementation leads to immediate and long term lowering of plasma homocysteine in healthy men and women - PubMed
High plasma homocysteine is a risk for cardiovascular disease and can be lowered through supplementation with 6 g/d of betaine. However, dietary intake of betaine is approximately 0.5-2 g/d. Therefore, we investigated whether betaine supplementation in the range of dietary intake lowers plasma...pubmed.ncbi.nlm.nih.govEffects of betaine on performance and body composition: a review of recent findings and potential mechanisms - PubMed
Betaine is a methyl derivative of glycine first isolated from sugar beets. Betaine consumed from food sources and through dietary supplements presents similar bioavailability and is metabolized to di-methylglycine and sarcosine in the liver. The ergogenic and clinical effects of betaine have...pubmed.ncbi.nlm.nih.govBetaine supplementation is associated with the resilience in mice after chronic social defeat stress: a role of brain-gut-microbiota axis - PubMed
These findings suggest that betaine supplementation contributed to resilience to anhedonia in mice subjected to CSDS through anti-inflammation action. Therefore, it is likely that betaine could be a prophylactic nutrient to prevent stress-related psychiatric disorders.pubmed.ncbi.nlm.nih.govInvestigation of betaine as a novel psychotherapeutic for schizophreniaDietary Betaine Supplementation Increases Fgf21 Levels to Improve Glucose Homeostasis and Reduce Hepatic Lipid Accumulation in Mice
Identifying markers of human insulin resistance may permit development of new approaches for treatment and prevention of type 2 diabetes. To this end, we analyzdiabetes.diabetesjournals.org