serotonin

  1. Jwicks1995

    Wanting to start thyroid - energy / metabolism issues

    I’m only 26 and these issues have been plaguing me for over 8 years now. It seems my system is always running on empty and overdrive at the same time. My cognition is dismal. I feel like I don’t actually sleep. I’m never rested, my mood is blank and I always feel hungry. Yet food doesn’t satisfy...
  2. haidut

    10-Methoxy-Harmalan - liquid product for R&D

    The chemical has already been discussed in another thread (see 1st link in References below), so this is just the announcement that it is now available for purchase. The units listed on the label are just for measurement purposes. They do not indicate or suggest optimal dose. Please note that...
    • haidut
    • Thread
    • 10-meo-harmalan 10-methoxy-harmalan 5-ht antagonist carboline ergot harmalan serotonin
    • Replies: 398
    • Forum: IdeaLabs
  3. A

    Stearic acid attenuates profibrotic signalling in idiopathic pulmonary fibrosis

    Background and objective: Lipid metabolism dysregulation has been implicated in the pathogenesis of IPF; however, the roles of most lipid metabolites in lung fibrosis remain unexplored. Therefore, we aimed to identify changes in lipid metabolites in the lung tissues of IPF patients and determine...
  4. JamesGatz

    What causes the feelings of having a crush on someone and having difficulty getting over an ex ? Is it just serotonin and oxytocin ?

    I notice that when I am low serotonin - I don't really have feelings in the sense of romantic relationships - I don't get jealous nor do I care for any of my exes or any girl that I have ever talked to or made a connection with - I feel like talking to girls and having relations with them but I...
  5. JamesGatz

    Does the mere action of gripping an object firmly reduce serotonin ?

    I believe I recall a quote I read by RP that said something along the lines of when speaking about serotonin in dogs - I believe it was a situation where they needed to restrain the dog - that if the dog was given something hard to clamp down on (like a bone) then their serotonin would lower...
  6. haidut

    High (extracellular) serotonin causes Alzheimer's and depression

    The utter corruption of "journalism" is once again on full display in MSM. The actual scientific study is very clear in its statements/conclusions that a decrease in the levels of serotonin transporter (5-HTT) led to accumulation of beta-amyloid and onset of depression. Lower levels of 5-HTT -...
    • haidut
    • Thread
    • 5-ht 5-htt alzheimer dementia depression serotonin serotonin transporter sert
    • Replies: 22
    • Forum: Scientific Studies
  7. JamesGatz

    Laughing increases serotonin and seems to increase Nitric Oxide ?

    I think most of us can agree that we all "feel better" when laughing but a few things I found interesting was this: https://www.forbes.com/sites/daviddisalvo/2017/06/05/six-science-based-reasons-why-laughter-is-the-best-medicine/?sh=6acf1467f04f "Laughter has an effect similar to...
  8. JamesGatz

    Why are squirrels so jumpy and why are Black Bears cowards ?

    I think we should have a discussion on the true nature of squirrels - I notice that squirrels typical diet (nuts) is high in PUFA - Every squirrel I meet seems to exhibit high-serotonin behavior and seems to jump away at the first sign of trouble. I saw this degenerate video on YouTube of a...
    • JamesGatz
    • Thread
    • bears serotonin squirrels
    • Replies: 11
    • Forum: Animals
  9. JamesGatz

    Choosing the right air filter - Why most air filters on the market are DANGEROUS

    Why many air filters are Dangerous I wanted to create this thread because of the topic of air filters - they seem to really help in my room and household with reducing serotonin - However in another thread @Mr.Bollox brought up ionizing and UV air filters so I think it's good to have a...
  10. JamesGatz

    Why there is no such thing as children being afraid of the dark and why people like sleeping "under the covers"

    Why are night lights so popular especially among young children ? Why do people like laying "under the covers" while sleeping ? Because darkness increases serotonin and what decreases serotonin ? Being in a dimly lit room would decrease the serotonergic response from being in a pitch black...
  11. JamesGatz

    My theory on why being born with curly hair is superior and perceived as more physically attractive

    I notice that when I wear headwear (such as a cap or a beanie or over a t-shirt over my head - I get a great boost in temps/metabolism and serotonin is lowered tremendously - I suspect because a raise in temps in the brain (head insulation) helps boost metabolism I notice that people with very...
  12. haidut

    Maternal SSRI/SNRI use leads to offspring addiction/withdrawal

    After being told for decades that SSRI/SNRI drugs are safe for usage during pregnancy, now the truth finally starts to come out. Well, technically it has been out for a long time considering the skyrocketing autism rates and the strong causal link between serotonin and autism. However, up until...
    • haidut
    • Thread
    • 5-ht addiction pregnancy serotonin snri ssri withdrawal
    • Replies: 1
    • Forum: Scientific Studies
  13. haidut

    Lowering/blocking serotonin is therapeutic for cancer

    One of the few studies that is brave enough to point the finger directly at serotonin as a tumor-promoter. Mainstream medicine has acknowledged that serotonin has a growth-promoting effects, but only in one specific tumor - carcinoid syndrome - and refuses to admit that the same growth-promoting...
    • haidut
    • Thread
    • 5-ht cancer colon immune system pancreatic serotonin t-cell tph
    • Replies: 2
    • Forum: Scientific Studies
  14. miquelangeles

    Serotonin derivatives, phytoserotonin

    Anyone knowledgeable on this subject? Some of them seem beneficial. Serotonin derivatives from safflower seed for example seem to improve vascular elasticity and decrease atherosclerosis in animal experiments, which suggests they might act as serotonin antagonists.
  15. haidut

    SSRI drugs decrease androgens / progestogens, increase estrogens

    As hard as it is to believe, this is the actual title of the study - i.e. SSRI drugs are bonafide endocrine disruptors. As it turns out, all of the six most-prescribed SSRI drugs the study looked at behaved not only as inhibitors of gonadal androgen synthesis (e.g. testosterone, DHT), but also...
    • haidut
    • Thread
    • antiandrogenic antidepressant aromatase endocrine disruptor estrogenic serotonin ssri
    • Replies: 6
    • Forum: Scientific Studies
  16. limitless77

    Can SSRIs help someone who is depressed

    I've been following raypeat ideas for some time now and I know that he is against serotonin, but I'm desperate and I've did some research about SSRIs and from my understanding they don't raise the production of serotonin in the body like tryptophan and 5-htp do, but they keep the serotonin...
  17. A

    Real-world evidence for improved outcomes with Famotidine and Aspirin in 22,560 COVID-19 patients

    When delivered at high doses (the equivalent of about 10 Pepcid tablets), famotidine appears to improve the odds of survival for COVID-19 patients, especially when it is combined with aspirin. It also seems to hinder the severity of disease progression, making patients less likely to reach the...
  18. haidut

    Serotonin puts the brakes on libido, by lowering dopamine

    Nothing really surprising, as far as Peatarians are concerned, in the findings of this study. I am only posting it here as it is one of the few that officially acknowledge that serotonergic drugs cause sexual dysfunction - i.e. something mainstream medicine has vehemently denied for decades. As...
    • haidut
    • Thread
    • dopamine fertility infertility libido pssd serotonin ssri stress
    • Replies: 2
    • Forum: Scientific Studies
  19. Drareg

    Regulation of systemic energy homeostasis by serotonin in adipose tissues

    Not sure if this was posted on here yet, it’s interesting that 5ht is so active in adipose tissue. Maybe topical application of a 5HT3 antagonist on adipose tissue may be helpful for people struggling in this area? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403443/ Inhibition of 5-HT...
  20. A

    !COVID-19 or Tryptophan Syndrome

    SARS-CoV-2, a new virus, which has been causing the catastrophic pandemic in the world in 2020, triggers numerous physiologic changes in humans, with potentially fatal evolution due to COVID-19. COVID-19 can trigger immunoparalysis with deep and silent immunosuppression and a state of tolerance...
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