serotonin

  1. NewACC

    Aspirin Cause Antiserotonine Effect Only At Low Doses (My Vision of the Non-Linear Dose-Dependent Antiserotonin Effect of Aspirin)

    Dear peats! As you all know, serotonin has a direct aggregative coagulant effect through the 5-ht2 family of receptors. And so, aspirin has the strongest antiplatelet effect at doses below 325 mg. We also know that aspirin has the most potent beneficial effect on tyrosine hydroxylase at a...
    • NewACC
    • Thread
    • 5-ht2 antiaggregation antiserotonin aspirin aspirin low dose low dose microdosing serotonin trh tyrosine-hydroxylase
    • Replies: 10
    • Forum: Cortisol, Serotonin, Histamine
  2. NewACC

    My Vision of the Non-Linear Dose-Dependent Antiserotonin Effect of Aspirin

    Dear peats! As you all know, serotonin has a direct aggregative coagulant effect through the 5-ht2 family of receptors. And so, aspirin has the strongest antiplatelet effect at doses below 325 mg. We also know that aspirin has the most potent beneficial effect on tyrosine hydroxylase at a...
  3. haidut

    BOMBSHELL: Serotonin High in Depression, Not a "Happy" Chemical, Lowers Energy, Depression Self-Resolves

    When I first saw the article pop up in my feed, I could hardly believe my eyes that a mainstream mouthpiece of Big Pharma will publish such frank admission of psychiatry's utter failure - i.e. the claims in regards to serotonin (5-HT), its role in mental illness, and even its social "label". In...
    • haidut
    • Thread
    • 5-ht depression energy metabolism oxphos serotonin ssri suicide
    • Replies: 32
    • Forum: Scientific Studies
  4. haidut

    Just a week-long break from social media alleviates anxiety and depression

    I don't think this study will come as a surprise to my readers, but it still helps to have some peer-reviewed evidence confirming what many people intuitively sense, yet are afraid to verbalize due to FOMO or being ostracized - i.e. social media, and digitization in general, is a bane on human...
    • haidut
    • Thread
    • abstinence anxiety depression fomo mental health routine serotonin social media
    • Replies: 19
    • Forum: Scientific Studies
  5. Hans

    Shilajit on testosterone, dopamine and sexual function

    https://men-elite.com/2022/05/13/shilajit-on-testosterone-dopamine-and-sexual-function/ What has been your experience with shilajit?
  6. haidut

    Dopamine agonists can treat anhedonia

    The title may sound obvious to many, but this study is one of the few to bring up the taboo topic of serotonin's role in symptoms of depression. The current dogma still holds that raising serotonin levels (or activating its receptors) is the most beneficial mechanism to treating depression and...
  7. tastyfood

    What number do you aim for when you test blood serotonin?

    I've been testing blood serotonin occasionally. Six months ago I was at 199 ng/mL. The lab range is 21-321. Two weeks ago I tested 148. The main differences I introduced were taking fewer oral supplements, and eating 1/3 a cup of oat bran every morning which has been really helpful for bowel...
  8. haidut

    Quinine - liquid product for R&D

    Just a placeholder thread for now, until I organize all the references I think would be interesting/relevant to post here. For now, a quote from Peat on a recent interview about quinine and inflammation/ACE2, a very long thread/discussion in regards to quinine's anti-serotonin effects, and some...
    • haidut
    • Thread
    • 5-ht ace2 angiotensin carnitine carnitine depletion dopamine fatty acid oxidation inflammation meldonium oct2 octn2 quinine serotonin
    • Replies: 98
    • Forum: IdeaLabs
  9. haidut

    Cyproheptadine (12mg daily) cures patient's metastatic liver cancer in just 2 weeks

    A truly shocking case study, which demonstrates once again how even terminal disease are often curable with cheap, safe, and widely available compounds that have long ago been written off as "obsolete" by mainstream medicine. More importantly, the case study highlights the core role metabolism...
    • haidut
    • Thread
    • 5-ht cure cyproheptadine hcc histamine liver cancer metastatic serotonin
    • Replies: 21
    • Forum: Scientific Studies
  10. Grouptose

    Serotonin causes autism

    I really don't know what it is, but every single serotonergic substance or medication I have ever tried turned me into either an aspie, or a complete autist. It all started back in 2017 when I had insomnia, I was a pretty normal person but had trouble sleeping, a doctor prescribed melatonin...
    • Grouptose
    • Thread
    • autism serotonin ssri
    • Replies: 5
    • Forum: Autism
  11. haidut

    Blocking serotonin may treat leukemia and other blood cancers

    Yet another cancer is revealed to be metabolic of origin and potentially treatable with cheap and widely available anti-serotonin chemicals (e.g. Benadryl, cyproheptadine, the ergot derivatives, etc). Conversely, the study raises serious questions in regards to whether the explosion in blood...
    • haidut
    • Thread
    • 5-ht cancer kynurenine leukemia myelodysplastic osteoblasts serotonin tryptophan
    • Replies: 1
    • Forum: Scientific Studies
  12. C

    Need some help with SSRI/Faverin Withdrawal

    So my friend's younger sister has been prescribed faverin and other SSRIs for her BPD, and after 4 months and increasingly depressive behaviour and suicidal ideation(she was tired all the time, felt like she "needed" to kill herself jumping off a roof, amongst other deeply concerning symptons)...
  13. A

    Charles Darwin’s Mitochondrial Disorder: Possible Neuroendocrine Involvement

    Abstract Charles Darwin, the famous naturalist, suffered relapsing, debilitating illness for most of his adult life with a plethora of symptoms. The diagnosis favoured here for this illness is that of an adult-onset mitochondrial disorder due to a maternally inherited, pathological mitochondrial...
  14. JamesGatz

    Is low serotonin always associated with higher social status ? Throughout the animal kingdom there seems to be conflicting ideas

    I was reading through an older thread on the forum and saw a user say something along the lines of serotonergic chimpanzees being the leaders of their group ? I am not sure what to think because from what I notice in people - low-serotonin attitudes seems to always imply higher social status...
    • JamesGatz
    • Thread
    • anti-depressant chimpanzees primates prozac serotonin social status
    • Replies: 14
    • Forum: Miscellaneous
  15. A

    Post-Traumatic Stress Disorder as an Endothelial Disease: Insights From COVID-19

    SARS-CoV-2 virus, the etiologic agent of COVID-19, has affected almost every aspect of human life, precipitating stress-related pathology in vulnerable individuals. As the prevalence rate of posttraumatic stress disorder in pandemic survivors exceeds that of the general and special populations...
  16. A

    The Anti Depression Pills that may Kill Cancer

    https://www.cancertreatmentsresearch.com/the-anti-depression-pills-that-kill-cancer Introduction Due to various reasons such as fast cellular division, cancer treatments, or during the spread through the body, cancer cells often end up with damaged cell membrane (Ref.). This is why cancer cells...
    • aliml
    • Thread
    • cancer imipramine nicolsamide serotonin
    • Replies: 1
    • Forum: Cancer
  17. Lokzo

    Does serotonin deficiency lead to anosmia, ageusia, dysfunctional chemesthesis and increased severity of illness in COVID-19?

    Does serotonin deficiency lead to anosmia, ageusia, dysfunctional chemesthesis and increased severity of illness in COVID-19? Amarnath Sen Author information Article notes Copyright and License information Disclaimer This article has been cited by other articles in PMC. Go to: Abstract...
  18. P

    Best way to approach gut issues

    Hello all, My journey peating has been wonderful so far. Diet, thyroid, etc. have all been addressed and I feel better than I have for years. I'm still seeing near daily improvements primarily from supplementing thyroid. The next thing I want to tackle is my gut. I pretty much don't tolerate...
    • PointOutside
    • Thread
    • brain fog constipation gut gut inflammation serotonin
    • Replies: 23
    • Forum: Digestion
  19. Lokzo

    The High Serotonin Personality

    View: https://www.youtube.com/watch?v=UjBpfAQFRuM
  20. haidut

    Serotonin, SSRI drugs may be the cause of IBD, Parkinson's, diabetes, etc.

    A great new study that points the finger straight at serotonin (5-HT). It has been known since the 1940s that not only is 5-HT produced predominantly in the GI tract, but also that elevated serotonin levels are causally linked to a plethora of chronic conditions, especially various inflammatory...
    • haidut
    • Thread
    • 5-ht autoimmune autophagy cancer diabetes ibd inflammation parkinson serotonin
    • Replies: 31
    • Forum: Scientific Studies
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