endotoxin

  1. haidut

    Blocking The Endotoxin (TLR4) Receptor May Protect From Ebola Lethality

    The connection between the "flu" and endotoxin has been explored at length by Peat. However, recent evidence has accumulated that quite a few other viruses and the terrible infections they cause may me mediated either by the endotoxin load they increase or by the viruses themselves activating...
    • haidut
    • Thread
    • antagonist ebola endotoxin infection lps therapeutic tlr4 virus
    • Replies: 4
    • Forum: Scientific Studies
  2. haidut

    Bladder Dysfunction And Incontinence Likely Due To Endotoxin (TLR4)

    Ray has mentioned a few times over email to people that bladder irritation or even kidney problems are likely due to increased endotoxin load. My urologists friends laugh so hard when I mention this in our discussions, but lately they seem more gloomy than amused. I suspect that this new study...
    • haidut
    • Thread
    • bladder diabetes dysfunction endotoxin incontinence inflammation tlr4
    • Replies: 6
    • Forum: Scientific Studies
  3. P

    Voluntary Activation Of The Sympathetic Nervous System And Attenuation Of The Innate Immune Response

    Voluntary activation of the sympathetic nervous system and attenuation of the innate immune response in humans. - PubMed - NCBI Excessive or persistent proinflammatory cytokine production plays a central role in autoimmune diseases. Acute activation of the sympathetic nervous system attenuates...
    • paymanz
    • Thread
    • adrenaline endotoxin epinehprine flu immune system inflammation meditation stress sympathetic nervous system tnf
    • Replies: 1
    • Forum: Articles & Scientific Studies
  4. haidut

    Serotonin Production In The Gut Is Fully Controlled By Microbiome

    A year and a half ago I posted about a study which found that serotonin production in the gut depends on the bacteria living in the colon. Serotonin Production (gut) Depends On Bacteria At the time, the study was considered controversial as the role of microbiome in serotonin production was...
    • haidut
    • Thread
    • bacteria endotoxin gut lps microbiome serotonin serotonin transporter ssri tlr2
    • Replies: 44
    • Forum: Scientific Studies
  5. haidut

    Endotoxin (LPS) Is A Probable Cause For Chronic Fatigue Syndrome (CFS / ME)

    It seems like the bad news about endotoxin (LPS) just don't stop. After the recent studies implicating in many degenerative conditions, and especially Alzheimer, systemic sclerosis, ALS, etc not this study links it to the so-called chronic fatigue syndrome (CFS / ME), which the medical...
    • haidut
    • Thread
    • cfs chronic fatigue syndrome endotoxin lps me myalgic encephalopathy pge2 prostaglandins tlr4
    • Replies: 6
    • Forum: Scientific Studies
  6. haidut

    Endotoxin (LPS) May Be A Causative Factor In Alzheimer Disease (AD)

    I posted recently about a study that found many of the chronic degenerative diseases can be traced back to endotoxin and excess iron. Endotoxin And Iron Finally Recognized As Potential Causes Of Many Diseases This study went a step further and identified endotoxin (LPS) in the brains of AD...
    • haidut
    • Thread
    • alzheimer's bacteria brain endotoxin lps neurodegenerative tlr4
    • Replies: 17
    • Forum: Scientific Studies
  7. haidut

    Low Social Status Damages The Immune System

    I have posted before on the link between status and health and I think user @Such_Saturation also posted a study on reversal of dominant social status leading to serotonergic dominance. This latest study shows that it is the relative difference of social status that matters. So, even though a...
    • haidut
    • Thread
    • chronic stress endotoxin immune system immunity inflammation lps social isolation social status tlr4
    • Replies: 27
    • Forum: Scientific Studies
  8. haidut

    Vitamin B2 (riboflavin) Positively Modulates The Microbiome

    I posted a few studies recently showing that riboflavin has an anti-endotoxin effect and protects from colonic inflammation. Apparently, in addition to its direct effects on the TLR4 receptor, riboflavin is capable of actually changing the microbiome composition when used as a supplement. It...
    • haidut
    • Thread
    • bacteria c. difficile colon endotoxin microbiome modulator riboflavin vitamin b2
    • Replies: 68
    • Forum: Scientific Studies
  9. haidut

    Systemic Sclerosis (scleroderma) May Be Due To Endotoxin; Blocking TLR4 Can Treat It

    In a recent interview Peat explained the connection between endotoxin, hypothyroidism, and rheumatoid arthritis. I recently posted a study claiming that chronic activation of the endotoxin receptor TLR4 synergizes greatly with iron and is probably a causative factor in many degenerative...
    • haidut
    • Thread
    • antagonist endotoxin lps reverse scleroderma systemic sclerosis tlr4 treatment
    • Replies: 5
    • Forum: Scientific Studies
  10. haidut

    Blocking Endotoxin (TLR4) Can Prevent Pre-term Birth

    The number of so-called preemies has been steadily rising over the last 2 decades. The official explanation is that the cause is unknown, but the only officially approved treatment is progesterone. This study sheds a bit more light and claims that endotoxin is behind the majority of cases of...
    • haidut
    • Thread
    • article endotoxin naloxone pre-term labor preemie prevention tlr4
    • Replies: 5
    • Forum: Scientific Studies
  11. haidut

    Glycine Is An Endotoxin (TLR4) Antagonist

    We can now add glycine to the substances that inhibit endotoxin or its effects. The endotoxin antagonism probably explains a good deal of glycine's protective effects on the liver from all sorts of assaults, but especially ethanol/alcohol (which is a known TLR4 agonist). The in-vivo study used a...
    • haidut
    • Thread
    • antagonist endotoxin glycine lipopolysaccharide liver lps study tlr4 tnf
    • Replies: 37
    • Forum: Scientific Studies
  12. raypeatclips

    Caffeine Decreases Nitric Oxide (NO) , Cox-2 Inhibitor

    Didn't see this posted and is a fairly new study. Also, does anyone any ideas how this relates to endotoxin? I am quite new at looking at studies. Caffeine prevents LPS-induced inflammatory responses in RAW264.7 cells and zebrafish. - PubMed - NCBI " Caffeine decreased the LPS-induced...
  13. haidut

    Nitrix Oxide (NO) Is A Likely Cause Of Migraines

    The good thing about this study is that it finally makes the connection between the known neurotoxin NO and the pathology of migraines. The bad thing about this study is that it still refers to NO as a heart-protective chemical and it also tries to blame the elevated levels of NO on specific gut...
    • haidut
    • Thread
    • endotoxin gut flora microbiome migraine nitrates nitric oxide study
    • Replies: 54
    • Forum: Scientific Studies
  14. S

    Endotoxin, Obesity And Diabetes (Podcast)

    Greetings, this is the first in a series of podcasts looking at our old friend endotoxin. I have a look at some rodent studies relating to diabetes, obesity, "metabolic syndrome" and NAFLD/NASH. Biocast Episode 009 – Endotoxin, Obesity and Diabetes | Resonant FM
    • Sucrates
    • Thread
    • diabetes endotoxin obesity
    • Replies: 14
    • Forum: Blogs
  15. haidut

    Low-dose DHEA Inhibits Aromatase By 35% And Endotoxin Blocks That Effect

    I found this study while researching the conversion of DHEA into steroids with immunomodulating effects. As you can see (attached picture), a DHEA concentration of 1µM inhibited aromatase activity by about 35%. This concentration of DHEA can be easily achieved with 3mg - 5mg topical DHEA in...
  16. haidut

    DHEA Protects From Endotoxin Effects And Lethality

    Sepsis is the leading cause of death in patients hospitalized for infections. There is no accepted treatment, at least officially, that can change the course of the sepsis for the better. This study shows that a single HED dose of as little as 5mg - 7mg daramatically increased survival from a...
    • haidut
    • Thread
    • cortisol dhea endotoxin lethality lps prevention protective tnf
    • Replies: 2
    • Forum: Scientific Studies
  17. M

    Endotoxin And Iron Finally Recognized As Potential Causes Of Many Diseases

    [ moderator edit: threads merged ] Bacteria lurking in blood could be culprit in countless diseases
    • Miso
    • Thread
    • als alzheimer's arthritis bse cancer clotting cvd endotoxin fibrin heart attack inflammation iron lps stroke thrombosis
    • Replies: 55
    • Forum: Scientific Studies
  18. M

    K2 And Endotoxin

    Does anyone know (or is able to venture an educated guess) on whether or not you need to swallow the vitamin K2 in order for it to have an effect on endotoxin? I've been rubbing the K2 into my gums but am now thinking I might be better off putting the drops in a liquid and drinking it in order...
    • marikay
    • Thread
    • endotoxin supplemental vitamin k vitamin k2
    • Replies: 14
    • Forum: K
  19. haidut

    Vitamin A (retinol) Is Endotoxin (LPS / TLR4) Antagonist

    Another one in the series of endotoxin antagonism featuring so far vitamins D and B2. Vitamin B2 (riboflavin) Is Endotoxin Antagonist Vitamin B2 Remarkably Effective Against Endotoxin, Sepsis, And Other Bacterial Infections Vitamin D Is Endotoxin (LPS / TLR4) Antagonist, May Treat LPS-linked...
    • haidut
    • Thread
    • antagonist endotoxin fibrosis inflammation lps retinol tlr4 vitamin a
    • Replies: 19
    • Forum: Scientific Studies
  20. haidut

    Vitamin B2 (riboflavin) Is Endotoxin (LPS / TLR4) Antagonist

    This is just a follow up on the recent post on both riboflavin and vitamin D. Vitamin B2 Remarkably Effective Against Endotoxin, Sepsis, And Other Bacterial Infections https://raypeatforum.com/community/threads/vitamin-d-is-endotoxin-lps-tlr4-antagonist-may-treat-lps-linked-conditions.12060/...
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