endotoxin

  1. haidut

    Pregnenolone Is A Potent (functional) Endotoxin (TLR4) Antagonist

    It seems that pregnenolone is finally starting to look exciting to the medical industry. In addition for its intensive studies for a variety of mental issues, now studies are coming out demonstrating its endotoxin (LPS) antagonism effects. As most forum users know, endotoxin exerts its effects...
    • haidut
    • Thread
    • alcoholism allopregnanolone alzheimer's antagonist cvd depression endotoxin epilepsy immune system inflammation lps ms multiple sclerosis pregnenolone ptsd schizophrenia sepsis tlr4 tnf
    • Replies: 10
    • Forum: Scientific Studies
  2. haidut

    Pyrucet - Liquid (ethyl) Pyruvate/Aceatoacetate Mix

    As many forum users know, I have been interested in the Randle Cycle (glucose/fat competition for oxidation) for quite some time. The topic of limiting fatty acid oxidation (FAO) and promoting glucose oxidation is pretty central to the metabolic theory of health. Peat has written many times on...
    • haidut
    • Thread
    • acetoacetate brain dementia endotoxin ethyl acetoacetate ethyl pyruvate fao fatty acid oxidation glucose oxidation gssg heart attack idealabs metabolism nad/nadh oxidation pdh pyruvate redox sepsis stroke
    • Replies: 602
    • Forum: IdeaLabs
  3. haidut

    A Common Probiotic Strain (lactobacillus) May Cause Lupus

    In one of his articles, Ray briefly mentioned the possible role of lactobacillus strains in the pathology of Lupus. Food-junk and some mystery ailments: Fatigue, Alzheimer's, Colitis, Immunodeficiency. Carrageenan "...The variations in the post-influenza syndromes are very likely influenced by...
    • haidut
    • Thread
    • autoimmune autoimmune disease cause endotoxin exacerbate gut flora lactobacilli lactobacillus lactobacillus reuteri lupus microbiome probiotic sle tlr7 trigger
    • Replies: 34
    • Forum: Scientific Studies
  4. haidut

    Endotoxin (and Baby Formula) May Be The Cause Of IBD And Brain Damage

    It is a well-publicized fact that people with inflammatory bowel disease (IBD) such as Crohn's and ulcerative colitis (UC) struggle with severe cognitive and mood issues. They are also at a much greater risk of developing dementia than the general population, and at a much younger age too...
    • haidut
    • Thread
    • baby formula brain damage cognitive impairment crohn's endotoxin formula ibd inflammatory bowel disease lps mental illness nec necrotizing enterocolitis stress tlr4 uc ulcerative colitis
    • Replies: 29
    • Forum: Scientific Studies
  5. ecstatichamster

    LPS (endotoxins) Kills Pain

    https://www.sciencedirect.com/science/article/pii/0006899394919089 Abstract Activation of the immune system in response to either infection or lipopolysaccharide (LPS) produces neurophysiological, neuroendocrine and behavioral changes. Some of the physiological consequences of LPS are mediated...
  6. haidut

    Low-protein High-carb Diet Has The Same Benefits As Caloric Restriction

    A recent study posted on the forum claimed that low carb is better for weight loss than other diets. Low Carb More Effective In Weight Loss Than High Carb? But the key question which so far most dieting studies ignore is this. Is the diet actually improving health and increasing lifespan...
    • haidut
    • Thread
    • benefit caloric restriction casein diet endotoxin fasting health high-carb lifespan longevity low-protein sucrose
    • Replies: 92
    • Forum: Scientific Studies
  7. haidut

    Soluble Fiber Causes Liver Cancer, Insoluble And Antibiotics Prevent/stop It

    Perhaps one of the most controversial topics in Peat-land is fiber. Over the years he has consistently recommended insoluble fiber, such as found in carrots/mushrooms/bamboo, while recommending explicitly against soluble fiber such as pectin and other fermentable starches. I think in one of his...
    • haidut
    • Thread
    • cancer cause dysbiosis endotoxin fos fructooligosaccharadise guar gum hcc inulin liver cancer lps microbiome pectin soluble fiber
    • Replies: 205
    • Forum: Scientific Studies
  8. haidut

    Periodontal Disease Can Cause Alzheimer's Disease (AD)

    Peat has written many times on the link between periodontal disease, and endotoxin. He mentioned how a few dentists he knows stopped doing dental cleaning after they found that that giving their patients laxatives or antibiotics cured their gum disease. In addition, a few studies came out...
    • haidut
    • Thread
    • alzheimer's bacteria cause endotoxin gingivitis gum disease inflammation neurodegenerative periodontal disease
    • Replies: 47
    • Forum: Scientific Studies
  9. haidut

    Saturated Fat (palmitate) Does NOT Activate TLR4

    We must have had hundreds of discussions on this topic on the forum. Some forum users strongly believe that saturated fat (SFA) increases inflammation by binding to and activating the endotoxin (LPS) receptor TLR4. Among all SFA, palmitate is the one most commonly blamed and has been...
    • haidut
    • Thread
    • disease endotoxin inflammation jnk lps obesity palmitate palmitic acid saturated fat sfa tlr4 vindicated
    • Replies: 28
    • Forum: Scientific Studies
  10. haidut

    The Benefits Of Fasting Are Due To Lowering Endotoxin (LPS), Not Less Calories

    As many of you know, the argument for/against fasting has been raging on the forum for several years at this point. While Ray has spoken several times favorably about potentially skipping a meal or two, he has repeatedly said that chronic fasting is not something he recommends due to its...
    • haidut
    • Thread
    • antagonist benefits caloric restriction cr diabetes endotoxin fasting inflammation lps microbiome obesity tlr4
    • Replies: 39
    • Forum: Scientific Studies
  11. haidut

    Aspirin May Prevent / Reduce HIV Infection In Humans

    A few years ago, I posted some studies showing that endotoxin is key in the development of AIDS. Those studies also found that without endotoxin, the HIV poses little risk to (healthy) organisms...
    • haidut
    • Thread
    • aids aspirin endotoxin hiv inflammation low-dose prevent prevention reduce systemic
    • Replies: 6
    • Forum: Scientific Studies
  12. haidut

    Endotoxin Causes (liver) Steatosis, Insulin Resistance And Atherosclerosis

    I know this study was in hepatitis C patients only, but there is nothing about Hep C that would invalidate this finding in the general population too. Quite a few people on the forum reported that when they tried to talk to their doctor about endotoxin and its possible role in their health...
    • haidut
    • Thread
    • atherosclerosis cvd endotoxemia endotoxin hepatitis inflammation insulin resistance liver lps steatosis tlr4
    • Replies: 16
    • Forum: Scientific Studies
  13. haidut

    Sterilizing The Gut Restores Insulin Sensitivity By Reducing Fatty Acid Oxidation

    I am posting this study just as an example of how important the role of endotoxin is in insulin resistance and diabetes. Similarly to the human study with aspirin, sterilizing the gut with antibiotics did not reduce the weight in the obese subjects (in this case mice). So, obesity may be a less...
    • haidut
    • Thread
    • antibiotics bacteria beta oxidation colon diabetes endotoxin fatty acid oxidation ffa gut insulin resistance insulin sensitivity lps microbiome obesity sterile sterilizing
    • Replies: 71
    • Forum: Scientific Studies
  14. haidut

    Pulmonary Fibrosis May Be Caused By Endotoxin (LPS)

    Ray spoken and written at length about endotoxin (LPS) and its role in virtually all chronic conditions. Mianstream medicine vehemently denies that LPS is an issue, except possibly for people with liver disease. But in thoses cases, the claim is that endotoxin may cause fever and diarrhea but...
    • haidut
    • Thread
    • endotoxin fibrosis inflammation lps pulmonary fibrosis scleroderma systemic sclerosis tlr4
    • Replies: 9
    • Forum: Scientific Studies
  15. haidut

    Simple Intestinal Antiseptic As A Cure For Rheumatoid Arthritis (RA)

    The role of endotoxin in RA and other "autoimmune" conditions has been discussed by Ray many times in his articles and interviews. Apparently, the connection was firmly established as causative back in the early 20th century and complete cures were often readily obtained using a simple phenolic...
    • haidut
    • Thread
    • autoimmune disease bacteria cure dimol emodin endotoxin intestinal permeability lps rheumatoid arthritis treat
    • Replies: 69
    • Forum: Scientific Studies
  16. haidut

    Osteoarthritis (OA) Is Driven By Endotoxin, Can Be Completely Reversed

    Unlike rheumatoid arthritis (RA), its "cousin" known as osteoarthritis (OA) is not generally believe to be due to chronic inflammation. The official cause of OA is "unknown" (just like RA) but often cited factors include genetics, excess weight, and advanced age. The study below points the...
    • haidut
    • Thread
    • arthritis endotoxin gut permeability inflammation lipopolysaccharide lps osteoarthritis prebiotic tlr4
    • Replies: 4
    • Forum: Scientific Studies
  17. haidut

    Pancreatic Cancer Driven By Bacteria/endotoxin; Antibiotics Can Prevent/treat

    I just posted a seminal study showing that possibly ALL autoimmune conditions may be caused by a chronic low-grade infection. This infection stems from a gut bacteria, which has translocated from the gut to the liver/lymphs due to compromised gut barrier and lingers there chronically thus...
    • haidut
    • Thread
    • ampicillin antibiotics bacteria bifidobacterium cancer cause endotoxin gut gut permeability lps microbiome pancreas pancreatic cancer tlr tlr4 tlr6 translocation
    • Replies: 15
    • Forum: Scientific Studies
  18. haidut

    Gut Bacteria May Cause ALL Autoimmune Conditions; Antibiotics Can Cure

    Ray has spoken/written at length about the importance of gut bacteria and the endotoxin they produce in virtually all chronic conditions. I posted a number of recent studies confirming the role of endotoxin (and iron) in a number of very serious conditions for which modern medicine claims there...
    • haidut
    • Thread
    • cirrhosis colon endotoxin gut gut permeability liver lps mesenteric lymph nodes microbiome mln
    • Replies: 263
    • Forum: Scientific Studies
  19. haidut

    Serotonin Causes Obesity And Diabetes In Humans

    This study is presented as groundbreaking and unexpected but in fact big pharma has been quietly working on anti-serotonin therapy for obesity/diabetes for more than a decade. I think the importance of this study is the admission that serotonin causes obesity/diabetes in humans, as one of the...
    • haidut
    • Thread
    • causative diabetes endotoxin gut humans insulin resistance metabolism obesity serotonin
    • Replies: 63
    • Forum: Scientific Studies
  20. haidut

    PUFA And Endotoxin (LPS) Inhibit Vitamin D And Thyroid Transport / Activity

    The "good" news for PUFA and endotoxin just keep on coming. I already posted a few studied showing that PUFA inhibits binding of androgens to their receptor and increases binding of estrogens to their receptor. This new study shows that PUFA and endotoxin inhibit the binding of vitamin D to...
    • haidut
    • Thread
    • activity binding endotoxin lps pufa receptor thyroglobulin thyroid thyroxine transport vitamin d
    • Replies: 8
    • Forum: Scientific Studies
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