Amazoniac
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Members that installed carpets at home to assist locomotion by gliding over colonies of microbes,
In this study, they randomly selected 54 hospitalized people and treated them with a "nourishing diet and supplements"*, then compared the outcome with 386 other hospitalized patients, and, as they noted, treated or not, they were more advanced cases. There was this premise that if infections (or other problems) were present (very common and varied), they were only accentuating the malnutrition; preceding and then contributing to the liver degeneration**. Treated patients were grouped by recovery, improvement (sometimes the length of monitoring was not long enough to consider the case a recovery) or failure. Regardless of the group, most of them were malnourished before admission, not just the ones that responded to the dietary intervention*** (crosses are scary).
In all groups there were some early deaths related or unrelated to degenerative processes.
TREATMENT OF CIRRHOSIS OF THE LIVER BY A NUTRITIOUS DIET AND SUPPLEMENTS RICH IN VITAMIN B COMPLEX
"Evidence of malnutrition was striking. [..] 81 per cent had eaten poor diets, and that 78 per cent had lost weight (allowing for ascites). Although careful dietary histories were taken, the data were not reliable enough to measure quantitatively."
"The most constant defects in the diets lay in the sparing use of meat and dairy products. Many patients gave histories of having subsisted entirely on alcoholic liquor for intervals of several days and of having refused all food during these sprees."
--
"It is known that the incidence of cirrhosis of the liver is high in certain countries where nutritional deficiencies are endemic (1, 2). Although malaria is blamed popularly for the high incidence of cirrhosis in these countries (3, 4), there is no direct evidence that malaria produces cirrhosis of the liver (5, 6)."
"It has been known that starvation renders the liver more vulnerable to injury by hepatotoxins (9). Lack of certain food factors contained in yeast are said to cause fatty changes in the liver (10) and impaired function (11)."
"It has also been shown that the feeding of excess fat (14) or of excess cystine (15) results in fibrotic changes in the liver."
"In a preliminary report on the treatment of 13 patients with alcoholic cirrhosis of the liver (21), it was noted that, in addition to signs of liver failure, there was evidence of specific malnutrition, notably of the vitamin B complex. These patients were fed a nutritious diet together with vitamin supplements. The improvement that followed treatment appeared to be outside chance expectations."
"The initial serum albumin value was low (below 4.0 grams per cent) in 96 per cent of the patients. The initial serum globulin value was high (above 3.0 grams per cent) in 83 per cent of the patients. ***It is noteworthy that the average initial value for serum albumin is higher in those patients who made clinical improvement than in those who failed to improve."
*
"In Table II is outlined the dietary regimen employed. The diet differs radically from that commonly advocated in this country for the treatment of cirrhosis of the liver, which is high in carbohydrate but low in protein and fat. The present diet contains a moderate amount of protein and fat. In addition to the protein of the diet (114 grams) the patients receive 50 grams of powdered Brewer's yeast 2 daily, of which the protein content is about 50 per cent. There has been no evidence of intolerance to fat in the amounts given. The stools do not contain excessive fat. Salt intake is restricted in patients with ascites and edema to the extent of omitting a salt shaker from the tray, and fluids are allowed up to 2,000 cc. daily. In the first group of 13 patients reported (21), vitamin B " complex " was provided daily in the form of autolyzed yeast (Vegex) or of aqueous liver extract (Valentine). Brewer's yeast was then substituted for these concentrates because it was found to be more palatable in large amounts. In addition to the yeast, the patients generally received intramuscular injections of concentrated liver extract, 5 cc. twice weekly (Lilly or Lederle), and of thiamin chloride,8 5 mgm [mg]. daily."
"The typical patient with cirrhosis of the liver might be described as follows: Characteristically, he has been bedridden for weeks or months. He has lost much weight. At entry he is weak and tired, mentally dull and at times confused. Food is loathsome. He complains of thirst, of abdominal fullness and pain. There is often lowgrade fever. The pulse rate is rapid. Breathing is shallow because of an elevated diaphragm."
"Although jaundice usually is of low grade, it takes weeks or months for this to subside completely."
"Recovery from polyneuritis in these patients is slow and usually incomplete. Functional improvement is striking in most instances, but the return of vibratory sensation may be partial, and the tendon reflexes may fail to return even after several years of intensive treatment with vitamin B concentrates."
"Several patients, whose ascites had disappeared for considerable periods of time and who had made clinical recovery from cirrhosis, died from intercurrent illness or accident."
**
"Studies on the metabolism of vitamin A (50) and vitamin K (51), for example, indicate that cirrhosis of the liver may interfere with the utilization of these vitamins. However, in many instances our patients gave histories of deficiency disease long antedating the symptoms or signs of cirrhosis. From these observations it seems likely that nutritional deficiency precedes the development of cirrhosis, and that the cirrhotic process, once established, tends to perpetuate or even aggravate the state of nutritional deficiency."
"It is difficult to separate signs of general bodily improvement from those that pertain to the funiction of the liver alone."
"It is realized that cirrhosis of the liver often is discovered at autopsy in persons dying from other causes. In these cases cirrhosis may have been latent for many years. In a series of 245 autopsies that showed cirrhosis of the liver, McCartney (47) found that 35 per cent had no previous clinical manifestations of the disease."
In this study, they randomly selected 54 hospitalized people and treated them with a "nourishing diet and supplements"*, then compared the outcome with 386 other hospitalized patients, and, as they noted, treated or not, they were more advanced cases. There was this premise that if infections (or other problems) were present (very common and varied), they were only accentuating the malnutrition; preceding and then contributing to the liver degeneration**. Treated patients were grouped by recovery, improvement (sometimes the length of monitoring was not long enough to consider the case a recovery) or failure. Regardless of the group, most of them were malnourished before admission, not just the ones that responded to the dietary intervention*** (crosses are scary).
In all groups there were some early deaths related or unrelated to degenerative processes.
TREATMENT OF CIRRHOSIS OF THE LIVER BY A NUTRITIOUS DIET AND SUPPLEMENTS RICH IN VITAMIN B COMPLEX
"Evidence of malnutrition was striking. [..] 81 per cent had eaten poor diets, and that 78 per cent had lost weight (allowing for ascites). Although careful dietary histories were taken, the data were not reliable enough to measure quantitatively."
"The most constant defects in the diets lay in the sparing use of meat and dairy products. Many patients gave histories of having subsisted entirely on alcoholic liquor for intervals of several days and of having refused all food during these sprees."
--
"It is known that the incidence of cirrhosis of the liver is high in certain countries where nutritional deficiencies are endemic (1, 2). Although malaria is blamed popularly for the high incidence of cirrhosis in these countries (3, 4), there is no direct evidence that malaria produces cirrhosis of the liver (5, 6)."
"It has been known that starvation renders the liver more vulnerable to injury by hepatotoxins (9). Lack of certain food factors contained in yeast are said to cause fatty changes in the liver (10) and impaired function (11)."
"It has also been shown that the feeding of excess fat (14) or of excess cystine (15) results in fibrotic changes in the liver."
"In a preliminary report on the treatment of 13 patients with alcoholic cirrhosis of the liver (21), it was noted that, in addition to signs of liver failure, there was evidence of specific malnutrition, notably of the vitamin B complex. These patients were fed a nutritious diet together with vitamin supplements. The improvement that followed treatment appeared to be outside chance expectations."
"The initial serum albumin value was low (below 4.0 grams per cent) in 96 per cent of the patients. The initial serum globulin value was high (above 3.0 grams per cent) in 83 per cent of the patients. ***It is noteworthy that the average initial value for serum albumin is higher in those patients who made clinical improvement than in those who failed to improve."
*
"In Table II is outlined the dietary regimen employed. The diet differs radically from that commonly advocated in this country for the treatment of cirrhosis of the liver, which is high in carbohydrate but low in protein and fat. The present diet contains a moderate amount of protein and fat. In addition to the protein of the diet (114 grams) the patients receive 50 grams of powdered Brewer's yeast 2 daily, of which the protein content is about 50 per cent. There has been no evidence of intolerance to fat in the amounts given. The stools do not contain excessive fat. Salt intake is restricted in patients with ascites and edema to the extent of omitting a salt shaker from the tray, and fluids are allowed up to 2,000 cc. daily. In the first group of 13 patients reported (21), vitamin B " complex " was provided daily in the form of autolyzed yeast (Vegex) or of aqueous liver extract (Valentine). Brewer's yeast was then substituted for these concentrates because it was found to be more palatable in large amounts. In addition to the yeast, the patients generally received intramuscular injections of concentrated liver extract, 5 cc. twice weekly (Lilly or Lederle), and of thiamin chloride,8 5 mgm [mg]. daily."
"The typical patient with cirrhosis of the liver might be described as follows: Characteristically, he has been bedridden for weeks or months. He has lost much weight. At entry he is weak and tired, mentally dull and at times confused. Food is loathsome. He complains of thirst, of abdominal fullness and pain. There is often lowgrade fever. The pulse rate is rapid. Breathing is shallow because of an elevated diaphragm."
"Although jaundice usually is of low grade, it takes weeks or months for this to subside completely."
"Recovery from polyneuritis in these patients is slow and usually incomplete. Functional improvement is striking in most instances, but the return of vibratory sensation may be partial, and the tendon reflexes may fail to return even after several years of intensive treatment with vitamin B concentrates."
"Several patients, whose ascites had disappeared for considerable periods of time and who had made clinical recovery from cirrhosis, died from intercurrent illness or accident."
**
"Studies on the metabolism of vitamin A (50) and vitamin K (51), for example, indicate that cirrhosis of the liver may interfere with the utilization of these vitamins. However, in many instances our patients gave histories of deficiency disease long antedating the symptoms or signs of cirrhosis. From these observations it seems likely that nutritional deficiency precedes the development of cirrhosis, and that the cirrhotic process, once established, tends to perpetuate or even aggravate the state of nutritional deficiency."
"It is difficult to separate signs of general bodily improvement from those that pertain to the funiction of the liver alone."
"It is realized that cirrhosis of the liver often is discovered at autopsy in persons dying from other causes. In these cases cirrhosis may have been latent for many years. In a series of 245 autopsies that showed cirrhosis of the liver, McCartney (47) found that 35 per cent had no previous clinical manifestations of the disease."
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