Serotonin As Inflammatory Mediator Of Chronic Eczema

[knockinondoors]

RP: Oh well -­ Coeliac disease is one of the causes of both skin disease and Arthritis. Coeliac disease, among other things, will allow endotoxin into your circulation and low thyroid is probably the most common thing associated with just ordinary eczema and that's because when your thyroid is low the circulation to your intestine is poor, the serotonin is high. The combination of endotoxin and the serotonin for example will cause the skin to have abnormal growth patterns.

The above quote is based on the notion of Ray Peat that
1. "autoimmune" doesn't exist
2. Eczema is a metabolic disorder leading to inflammation, and Serotonin is the player

There was a significantly stronger expression of serotonin in the prickle cells, sweat gland cells, sebaceous gland cells, and hair roots of the lesions in patients with chronic eczema. There was no positive expression of serotonin in normal skin.

Serotonin is probably important in the pathogenesis of chronic eczema. We demonstrated alterations in the expression of serotonin in chronic eczema lesions, which may in turn provide new insight into the pathogenesis of chronic eczema. Serotonin, along with cytokines, T lymphocytes, B lymphocytes, and macrophages, participates in the immune response and influences the inflammatory process by means of keratinocytes.

http://www.ncbi.nlm.nih.gov/pubmed/15485527

 

[mirc12354]

How would you go about healing eczema in (otherwise healthy) 3 years old?

 

[lexis]

Yellow color therapy can help