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Selenium may protect from EMR

Discussion in 'Scientific Studies' started by haidut, Oct 8, 2014.

  1. haidut

    haidut Member

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    The study was in vitro, but I think it still has some merit. Once again EMR appears to act primarily through suppressing metabolism. The only caveat is that selenium supplementation seems to generate toxicities for some people when administered chronically UNLESS vitamin E is also taken. When both selenium and vitamin E are taken the effects are synergistic and there is no toxicity of selenium.

    http://www.ncbi.nlm.nih.gov/pubmed/24965080

    "...Selenium suppressed EMR-induced oxidative cell damage and cell viability (MTT) through a reduction of oxidative stress and restoring mitochondrial membrane potential. Additionally, selenium indicated anti-apoptotic effects, as demonstrated by plate reader analyses of apoptosis levels and caspase-3 and caspase-9 values. In conclusion, 900 MHz EMR appears to induce apoptosis effects through oxidative stress and mitochondrial depolarization although incubation of selenium seems to counteract the effects on apoptosis and oxidative stress."
     
  2. Such_Saturation

    Such_Saturation Member

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    Interesting how vitamin E is associated with prostate cancer but not combined with selenium.
     
  3. Parsifal

    Parsifal Member

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    Which dosages for selenium and vitamin E should be considered for the protection? I've read that we should not have more than 400mcg/day? Does the vitamin E help selenium toxicity by balancing the thyroid T4/T3 ratio?

    :hattip
     
  4. OP
    haidut

    haidut Member

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    This study was in vivo and used a human equivalent dose of about 200mcg for 8 weeks.
    http://www.ncbi.nlm.nih.gov/pubmed/19396408

    And this human study used 350mcg selenium for reducing damage from ionizing radiation.
    http://www.ncbi.nlm.nih.gov/pubmed/12694822
     
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