Phenothiazine

[LeeLemonoil]

Impressive results in this study:

Phenothiazine normalizes the NADH/NAD+ ratio, maintains mitochondrial integrity and protects the nigrostriatal dopamine system in a chronic rotenone ... - PubMed - NCBI

Wouldn’t have expected that since this class of substances actually blocks D2-receptors

 

[GAF]

Phenothiazine - Wikipedia

Phenothiazine, abbreviated PTZ, is an organic compound that has the formula S(C6H4)2NH and is related to the thiazine-class of heterocyclic compounds. Derivatives of phenothiazine are highly bioactive and have widespread use and rich history. The derivatives chlorpromazine and promethazinerevolutionized the field of psychiatry and allergy treatment., respectively. An earlier derivative, methylene blue, was one of the first antimalarial drugs, and derivatives are under investigation as possible anti-infective drugs. Phenothiazine is a prototypical pharmaceutical lead structure in medicinal chemistry.