Here's Chris Masterjohn doing some complicated mental gymnastics to bring together the apparent toxicity of retinol with his idea that everyone is deficient in it:
"I posited that a respiratory chain disorder was causing one of my clients to require much higher than normal doses of vitamin A and zinc, was causing paradoxical coexistence of vitamin A deficiency and toxicity symptoms, and was driving her apparent autoimmune condition.
It later turned out that I was right on the money. This client had a complex III disorder traceable to six homozygous mutations in the MT-CYB gene. The whole genome sequencing reports did not report this at all. It was my analysis of the raw data file that found six homozygous mutations that lined up perfectly with a functional test of the respiratory chain."
Hopefully he will at one point realize that retinol simply suppresses the toxicity by making the body temporarily shuffle more retinol and retinyl esters into the liver.
It is simply not possible to have both toxicity and deficiency in a nutrient at the same time. The reason people come up with these ideas is that they don't understand that there is neither a vitamin A or a copper deficiency in the first place.
The faulty early rat studies that poisoned the rats and killed them with retinoic acid, which led to the establishment of "vitamin A deficiency" still rear their ugly head here, with people confusing deficiency symptoms with toxicity.
"I posited that a respiratory chain disorder was causing one of my clients to require much higher than normal doses of vitamin A and zinc, was causing paradoxical coexistence of vitamin A deficiency and toxicity symptoms, and was driving her apparent autoimmune condition.
It later turned out that I was right on the money. This client had a complex III disorder traceable to six homozygous mutations in the MT-CYB gene. The whole genome sequencing reports did not report this at all. It was my analysis of the raw data file that found six homozygous mutations that lined up perfectly with a functional test of the respiratory chain."
How I Found My Health “Super Unlock” After 20 Years of Research and 20,000 Genes Tested
Each person has one to six highly unique unlocks that will only work for them, and this is how to find them.
chrismasterjohnphd.substack.com
Hopefully he will at one point realize that retinol simply suppresses the toxicity by making the body temporarily shuffle more retinol and retinyl esters into the liver.
It is simply not possible to have both toxicity and deficiency in a nutrient at the same time. The reason people come up with these ideas is that they don't understand that there is neither a vitamin A or a copper deficiency in the first place.
The faulty early rat studies that poisoned the rats and killed them with retinoic acid, which led to the establishment of "vitamin A deficiency" still rear their ugly head here, with people confusing deficiency symptoms with toxicity.
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