Dr. Peat commonly refers to calcium being important for mitochondrial respiration, hence why milk/dairy consumption is advocated in the diet.
In one study I found online recently, the authors discussed a view quite contrarian to Peat’s (study found here:
“Calcium inhibits mitochondrial respiration in a dose-dependent manner...
Though the oxygen consumption increased initially upon addition of calcium and returned to State II respiration rates (Figure (Figure5),5), the later response to ADP was markedly affected, and this could be due to the transient depolarizing effect experienced with calcium on membrane potential. In one study, mitochondria exposed to a low Ca2+concentration (4 μM) resulted in a VDAC-mediated reversible cytochrome c release, whereas at a higher Ca2+ concentration (100 μM), there was mitochondrial inhibition due to mPT induced irreversible cytochrome c release (Schild et al., 2001).”
What do you guys make of this? I remember feeling good on tons of calcium initially but it quickly tapered off later on.
In one study I found online recently, the authors discussed a view quite contrarian to Peat’s (study found here:
“Calcium inhibits mitochondrial respiration in a dose-dependent manner...
Though the oxygen consumption increased initially upon addition of calcium and returned to State II respiration rates (Figure (Figure5),5), the later response to ADP was markedly affected, and this could be due to the transient depolarizing effect experienced with calcium on membrane potential. In one study, mitochondria exposed to a low Ca2+concentration (4 μM) resulted in a VDAC-mediated reversible cytochrome c release, whereas at a higher Ca2+ concentration (100 μM), there was mitochondrial inhibition due to mPT induced irreversible cytochrome c release (Schild et al., 2001).”
What do you guys make of this? I remember feeling good on tons of calcium initially but it quickly tapered off later on.