10 PSSD Recovery Tips And Tricks (herbs, Drugs And Strategies)

CalmAmygdala

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Oct 23, 2020
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Thank you. So here is something that has always perplexed me. Paroxetine has helped my anxiety tremendously. As I am tapering off, my anxiety is elevating. Do you know why this is? Why would paroxetine alleviate anxiety if it increases serotonin so potently? How can i combat this and is it temporary? Thanks for your insight
 

Frankdee20

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Thank you. So here is something that has always perplexed me. Paroxetine has helped my anxiety tremendously. As I am tapering off, my anxiety is elevating. Do you know why this is? Why would paroxetine alleviate anxiety if it increases serotonin so potently? How can i combat this and is it temporary? Thanks for your insight
Increasing the reuptake of serotonin will eventually downregulate receptors...
 

Hans

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Thank you. So here is something that has always perplexed me. Paroxetine has helped my anxiety tremendously. As I am tapering off, my anxiety is elevating. Do you know why this is? Why would paroxetine alleviate anxiety if it increases serotonin so potently? How can i combat this and is it temporary? Thanks for your insight
There could be a few reasons, but it potently increases brain neurosteroids, such as allopregnanolone (R, R). Perhaps you can try progesterone or 5a-DHP from Idealabs.
 

CalmAmygdala

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Oct 23, 2020
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It seems paroxetine reduces hyperactivity in the amygdala because of increased serotonin transporter binding. This would cause a reduction in arousal/anxiety. I wonder what other ways there are to soothe amygdala sensitivity.
 
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