Hey guys,
I'm observing an interesting sensation: every time I eat whole eggs, I get this kind of chest pain that lasts for a few hours, sometimes even until the next morning.
I don't feel that comfortable with this and also makes me a bit concerned about my heart health.
Back when I was...
I have always had very low cholesterol, and the necessity of taking thyroid meds has lowered it further. Various ways have been reported to increase cholesterol. The typically suggested methods to increase cholesterol include consuming extra cholesterol and consuming extra sugar.
I found only...
Abstract
Background: A recent cluster of pneumonia cases in Wuhan, China, was caused by a novel coronavirus COVID-19. Meanwhile, as the infection progressed, a large number of cases were also diagnosed in Wenzhou, China. The objective of the study is to describe the clinical laboratory features...
A pair of interesting study and a commentary in the highly respected Journals of Gerontology. Namely, higher cholesterol intake is associated with much higher lean muscle mass accrual as a result of weight lifting. Interestingly, higher protein intake was not. Even more interestingly, and much...
Yet another damning study on the toxic effects of drugs whose main effect (lowering cholesterol by blocking its synthesis) is already known to be harmful and has no evidence behind its claimed benefits. So, we can now add diabetes to the list of cancer, ALS, dementia, birth defects...
Several people asked Peat over email about the dangers of sun exposure. He responded by saying that the main danger is the lipid (PUFA) perodixation caused by the UV lights and that taking some aspirin, vitamin E, or niacinamide greatly reduces the damage.
The study below confirms that PUFA may...
Peat's most recent newsletter was on the topic of cholesterol and its increased esterification as a possible cause of the many pathologies that occur with aging.
Nov 2018: Dr. Peat Talks About Cholesterol Esters Causing Aging
One of the organs most vulnerable to cholesterol esterification is...
Abstract
Whole egg is a food source of dietary cholesterol and inconsistent research findings exist about the effect of dietary cholesterol from whole egg on blood cholesterol concentration. We assessed the effect of co-consuming cooked whole egg (CWE) on dietary cholesterol absorption from two...
This study probably won't come as surprise to forum users given what Ray has said and written about cholesterol. Without much fanfare, after more than 60 years of officially demonizing cholesterol in 2017 the FDA quietly reversed its position on recommending avoiding cholesterol. However, to...
"Cholesterol synthesis appears to be substantially decreased in livers of EFA deficient rats, whether deficiency is produced by a fat-free diet or a diet which contains 30% hydrogenated coconut oil. Nevertheless, cholesterol collects in the liver, primarily as cholesterol esters..."
I wonder if...
Cholesterogenesis to Steroidogenesis: Role of B2 in the Biosynthesis of D
From Cholesterogenesis to Steroidogenesis: Role of Riboflavin and Flavoenzymes in the Biosynthesis of Vitamin D
From Cholesterogenesis to Steroidogenesis: Role of Riboflavin and Flavoenzymes in the Biosynthesis of...
Pellagra is fairly well understood, but there is still some persistent mythology surrounding the etiology. Everyone knows that niacin is the characteristic deficiency, but few are aware of the central importance that leucine plays in this. The somewhat low tryptophan and niacin content of corn...
Was surprised when saw a study showing statins have positive effects on bones, did a bit of searching and it turned out that it has some positive action,generally, through inhibiting rho kinase, which also is protective against heart disease.
Im not promoting statin use at all(for obvious...
As most of the forum users know, MS is a chronic demyelination disease for which there is officially no cure. However, it is know that pregnant women experience complete remission and the condition exacerbates post-pregnancy, which emphasizes the protective role of progesterone and the...
I posted a few studies some time ago showing that HDL is associated with CVD mortality.
Good (HDL) Cholesterol Is Not So Good After All
Peat has spoken many times about the false claims of the medical industry that HDL is in fact the "good" cholesterol. HDL is most commonly elevated by stress...
Hepatic farnesyl diphosphate synthase expression is suppressed by polyunsaturated fatty acids. - PubMed - NCBI
Abstract
Dietary vegetable oils and fish oils rich in PUFA (polyunsaturated fatty acids) exert hypocholesterolaemic and hypotriglyceridaemic effects in rodents. The plasma...
Please don't just say "fat" or "amino acids."
Please don't just post a link to "cholesterol synthesis."
Please be specific.
Not dietary cholesterol. Cholesterol made by your liver.
The liver makes it, but from what?
Answer the question, what is the raw material cholesterol is made from?
.
I'm shockingly uninformed on the Peat-ey perspective on HDL, but maybe this explains some of the flaws in the "you should blindly increase HDL levels" idea:
HDL Composition May Help Predict Health Risks and Design Therapeutics
And the actual study:
HDL Glycoprotein Composition and Site-Specific...
The study used DHT as the active drug but since the positive effects were due to androgen receptor agonism, any other strong androgen agonist should do. I think the lack of estrogenicity also contributed to the benefits of DHT observed in this study, so this would explain the mixed results with...