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FDA approves non-statin drug to treat high cholesterol | CNN
The US Food and Drug Administration on Friday approved a drug to treat high cholesterol that works differently than statins, according to Esperion Therapeutics, the company that makes the drug.www.google.com
Thanks for responding. Yeah I know. Unfortunately my dad is on statins and since it’s hard to get him to not take his doctors advice on taking them I was hoping for the next best thing. A med that at least doesn’t do as much damage as statins.
Thyroid hormones and PUFA avoidance. Probably aspirin, gelatin and K2 combo too because inflammation tends to accompany high LDL and the one good thing statins do is lower inflammation. That being said:
He is on 15mg K2 and Aspirin as well as avoids PUFA. But his doctor won’t go for that being enough of course. He’ll push the statins on him unless there is another drug he can prescribe him. That’s why I was hoping maybe this new med isn’t as bad.
Yeah I don't think inhibiting cholesterol is good anywhere on the cholesterol pathway.FDA approves non-statin drug to treat high cholesterol | CNN
The US Food and Drug Administration on Friday approved a drug to treat high cholesterol that works differently than statins, according to Esperion Therapeutics, the company that makes the drug.
pubmed.ncbi.nlm.nih.gov
New drug is probably worse.
Thanks for the info JohnYeah I don't think inhibiting cholesterol is good anywhere on the cholesterol pathway.
This new drug is just upstream from HmG Co A reductase but still has some side effects.
Statins do have benefit but not through cholesterol - some are vitamin d analogs, lower inflammation/ros, improve endothelial function, thyroid analogs etc, basically pleiotropic actions not related to cholesterol.
Pharma won't let the Cholesterol thing slide they'll just invent a new class of drugs to get around people avoiding statins.
My doc wants me on a stating but I say no. I'm her boss she's not mine.
Taurine may be good to try:
The effect of taurine on cholesterol metabolism - PubMed
The elevated plasma cholesterol level, in particular, LDL cholesterol is regarded as an important risk factor for the development of atherosclerosis and coronary artery disease. A number of studies provide the evidence that taurine has the efficient action to reduce plasma and liver cholesterol...
pubmed.ncbi.nlm.nih.gov
Thanks manNot sure if you're still looking for non-statin options for your dad.
But here's an older article on policosanol vs lovastatin:
Comparative study of the efficacy and tolerability of policosanol and lovastatin in patients with hypercholesterolemia and noninsulin dependent diabetes mellitus - PubMed
This randomized, double-blind study was undertaken to compare the efficacy and tolerability of policosanol (10 mg/day) and lovastatin (20 mg/day) in patients with hypercholesterolemia and noninsulin dependent diabetes mellitus. After 6 weeks on a lipid lowering diet, 53 patients were randomized...
Policosanol beat lovastatin on all the cholesterol measurements without any of the liver side effects/etc.
Taurine + policosanol would probably be a nice stack hitting multiple cardiovascular, metabolic, inflammatory targets.
I heard the same about this guy on mamounis’ show, but why does he still go by carnivore Aurelius?
Hi, very good input on this thread. I’m wondering if you know whether or not policosanol has any effects on kidney function and blood pressure? ThanksNot sure if you're still looking for non-statin options for your dad.
But here's an older article on policosanol vs lovastatin:
Comparative study of the efficacy and tolerability of policosanol and lovastatin in patients with hypercholesterolemia and noninsulin dependent diabetes mellitus - PubMed
This randomized, double-blind study was undertaken to compare the efficacy and tolerability of policosanol (10 mg/day) and lovastatin (20 mg/day) in patients with hypercholesterolemia and noninsulin dependent diabetes mellitus. After 6 weeks on a lipid lowering diet, 53 patients were randomized...
Policosanol beat lovastatin on all the cholesterol measurements without any of the liver side effects/etc.
Taurine + policosanol would probably be a nice stack hitting multiple cardiovascular, metabolic, inflammatory targets.
Probably because he set up a business selling stuff like dehydrated liver
shop.carnivoreaurelius.com
Oh, I see, that makes perfect sense. My husband is probably right when he doesn’t want to listen to anyone selling something.Probably because he set up a business selling stuff like dehydrated liver
Beef Liver Crisps - Carnivore Aurelius
The First (And Only) Beef Liver That Actually Tastes Good.
There are a lot of things which can help/improve kideny function depending on what the issue(s) is/are.
