cholesterol

  1. haidut

    Statins More Than Double The Risk Of Diabetes Compared To Non-users

    Yet another damning study on the toxic effects of drugs whose main effect (lowering cholesterol by blocking its synthesis) is already known to be harmful and has no evidence behind its claimed benefits. So, we can now add diabetes to the list of cancer, ALS, dementia, birth defects...
  2. haidut

    PUFA/Statins Promote UV Damage & Skin Cancer (melanoma), Cholesterol Is Protective

    Several people asked Peat over email about the dangers of sun exposure. He responded by saying that the main danger is the lipid (PUFA) perodixation caused by the UV lights and that taking some aspirin, vitamin E, or niacinamide greatly reduces the damage. The study below confirms that PUFA may...
  3. haidut

    Increased Cholesterol Esterification As A Cause Of Alzheimer Disease (AD)

    Peat's most recent newsletter was on the topic of cholesterol and its increased esterification as a possible cause of the many pathologies that occur with aging. Nov 2018: Dr. Peat Talks About Cholesterol Esters Causing Aging One of the organs most vulnerable to cholesterol esterification is...
  4. Mito

    Dietary Cholesterol Contained In Whole Eggs Is Not Well Absorbed

    Abstract Whole egg is a food source of dietary cholesterol and inconsistent research findings exist about the effect of dietary cholesterol from whole egg on blood cholesterol concentration. We assessed the effect of co-consuming cooked whole egg (CWE) on dietary cholesterol absorption from two...
  5. haidut

    Eating 12 Eggs A Week Does Not Increase Risk Of Heart Disease

    This study probably won't come as surprise to forum users given what Ray has said and written about cholesterol. Without much fanfare, after more than 60 years of officially demonizing cholesterol in 2017 the FDA quietly reversed its position on recommending avoiding cholesterol. However, to...
  6. Luann

    Lowered Cholesterol In EFAD, Good Or Bad?

    "Cholesterol synthesis appears to be substantially decreased in livers of EFA deficient rats, whether deficiency is produced by a fat-free diet or a diet which contains 30% hydrogenated coconut oil. Nevertheless, cholesterol collects in the liver, primarily as cholesterol esters..." I wonder if...
  7. H

    Cholesterogenesis To Steroidogenesis: Role Of B2 In The Biosynthesis Of D

    Cholesterogenesis to Steroidogenesis: Role of B2 in the Biosynthesis of D From Cholesterogenesis to Steroidogenesis: Role of Riboflavin and Flavoenzymes in the Biosynthesis of Vitamin D From Cholesterogenesis to Steroidogenesis: Role of Riboflavin and Flavoenzymes in the Biosynthesis of...
  8. Travis

    On Pellagra

    Pellagra is fairly well understood, but there is still some persistent mythology surrounding the etiology. Everyone knows that niacin is the characteristic deficiency, but few are aware of the central importance that leucine plays in this. The somewhat low tryptophan and niacin content of corn...
  9. P

    Statins May Exert Beneficial Effects Through A Pathway Other Than It's Cholesterol Lowering Action

    Was surprised when saw a study showing statins have positive effects on bones, did a bit of searching and it turned out that it has some positive action,generally, through inhibiting rho kinase, which also is protective against heart disease. Im not promoting statin use at all(for obvious...
  10. haidut

    Taurine And T3 As Treatment For Multiple Sclerosis (MS)

    As most of the forum users know, MS is a chronic demyelination disease for which there is officially no cure. However, it is know that pregnant women experience complete remission and the condition exacerbates post-pregnancy, which emphasizes the protective role of progesterone and the...
  11. haidut

    High HDL Levels Are Associated With High All-cause Mortality

    I posted a few studies some time ago showing that HDL is associated with CVD mortality. Good (HDL) Cholesterol Is Not So Good After All Peat has spoken many times about the false claims of the medical industry that HDL is in fact the "good" cholesterol. HDL is most commonly elevated by stress...
  12. W

    PUFA Suppress Hepatic Farnesyl Diphosphate Synthase Expression

    Hepatic farnesyl diphosphate synthase expression is suppressed by polyunsaturated fatty acids. - PubMed - NCBI Abstract Dietary vegetable oils and fish oils rich in PUFA (polyunsaturated fatty acids) exert hypocholesterolaemic and hypotriglyceridaemic effects in rodents. The plasma...
  13. Westside PUFAs

    What Is The Raw Material Cholesterol Is Made From?

    Please don't just say "fat" or "amino acids." Please don't just post a link to "cholesterol synthesis." Please be specific. Not dietary cholesterol. Cholesterol made by your liver. The liver makes it, but from what? Answer the question, what is the raw material cholesterol is made from? .
  14. Dan W

    HDL Composition And Its Connections To Different Disease States

    I'm shockingly uninformed on the Peat-ey perspective on HDL, but maybe this explains some of the flaws in the "you should blindly increase HDL levels" idea: HDL Composition May Help Predict Health Risks and Design Therapeutics And the actual study: HDL Glycoprotein Composition and Site-Specific...
  15. haidut

    Strong Androgens (DHT) As Treatment For CVD, Obesity And Metabolic Syndrome

    The study used DHT as the active drug but since the positive effects were due to androgen receptor agonism, any other strong androgen agonist should do. I think the lack of estrogenicity also contributed to the benefits of DHT observed in this study, so this would explain the mixed results with...
  16. haidut

    The Thyromimetic Mechanism Of Androsterone (and Other Androgens)

    As I posted in one of the androsterone threads, studies in the first half of the 20th century discovered hypocholesteremic and pyrogenic effects of androsterone and many animal models and also in humans. However, the direct mechanism for these effects of androsterone was not elucidated by these...
  17. H

    Effects Of Excess Dietary Tyrosine On Cholesterol

    Effects of excess dietary tyrosine on cholesterol, bile acid metabolism and mixed-function oxidase system in rats. - PubMed - NCBI Effects of excess dietary tyrosine on cholesterol, bile acid metabolism and mixed-function oxidase system in rats. Nagaoka S1, Miyazaki H, Oda H, Aoyama Y, Yoshida...
  18. H

    Substances That Help Conversion Of Cholesterol Into Downstream Steroids And Bile Acids?

    @haidut has mentioned Androsterone (Thyroid mimetic) and Thyroid as substances that can help force 'the conversion of cholesterol into downstream steroids and bile acids'. Are there any other substances that are particularly good at doing this (as opposed to inhibiting cholesterol synthesis)?
  19. F

    Eggs Cut Chances Of Stroke. Massive New Study Confirms

    http://www.thetimes.co.uk/edition/news/an-egg-a-day-can-cut-chances-of-suffering-fatal-stroke-kr3lf0m3t
  20. haidut

    Androsterone As A Thyromimetic Treatment For Gout And CVD

    These studies are old, but I am just posting them here as further support of the thyromimetic properties of androsterone. As we know, thyroid hormone is the primary regulator of levels of uric acid and serum lipids and Ray has recommended improvement of thyroid function as the primary method for...
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