Taurine And Wound Healing

[Dan W]

Thanks to the large-brained Flávio:

The locally administreated taurine significantly increased wound tensile strength by decreasing the MDA and histamine levels and prevented the degranulation of the mast cells. These observations suggest that taurine may be useful on wound healing.

Pubmed source

And a second study with similar results from a gel form (maybe a product is in development?):

It was found that locally administered TAU-GEL form significantly increased wound tensile strength by decreasing the MDA and increasing HPX levels. These results were supported by histological findings. All observations suggest that taurine gel may be effective in wound healing.

Pubmed source

 

[aguilaroja]

Thanks for the findings!

This reference suggests that skin lesions from the parasite infection Leishmaniasis have improved healing with taurine either topical or systemic (injected). (Taurine did not reduce the number of parasites from the infection itself.)

Taurine improves the wound healing process in cutaneous leishmaniasis in mice model, based on stereological parameters. - PubMed - NCBI
Taurine improves the wound healing process in cutaneous leishmaniasis in mice model, based on stereological parameters.
Ashkani-Esfahani S1, Zarifi F1, Asgari Q2, Samadnejad AZ1, Rafiee S1, Noorafshan A3.
Adv Biomed Res. 2014 Oct 7;3:204. doi: 10.4103/2277-9175.142314. eCollection 2014.

There are, notably, two recent studies suggesting taurine may help gingival wound healing. (The first has different authors but comes from the same university center as the first article mentioned in the original post).

Effect of the topical use of the antioxidant taurine on the two basement membrane proteins of regenerating oral gingival epithelium. - PubMed - NCBI
Effect of the topical use of the antioxidant taurine on the two basement membrane proteins of regenerating oral gingival epithelium.
Gültekin SE1, Sengüven B, Sofuoğlu A, Taner L, Koch M.
J Periodontol. 2012 Jan;83(1):127-34. doi: 10.1902/jop.2011.100568. Epub 2011 May 16.
"RESULTS: Complete new epithelial formation was observed in 1% taurine-treated gingivectomy specimens, whereas incomplete regeneration of the epithelium was observed in control gingivectomy specimens (P <0.05). The length of the newly formed epithelium showed a negative correlation with inflammation in the taurine group (P = -0.712; P <0.05)."

This study used oral Taurine (only 500 mg once per day) after gum surgery, in a cross-over trial:

Evaluation of the efficacy of taurine as an antioxidant in the management of patients with chronic periodontitis. - PubMed - NCBI
Evaluation of the efficacy of taurine as an antioxidant in the management of patients with chronic periodontitis
Evaluation of the efficacy of taurine as an antioxidant in the management of patients with chronic periodontitis.
Sree SL1, Sethupathy S2.
Dent Res J (Isfahan). 2014 Mar;11(2):228-33
"...taurine seems to improve the antioxidant status of chronic periodontitis patients by influencing the levels of lipid peroxidation products (TBARS) and the antioxidant enzymes GPX and GSH. The apparent improvement observed in the clinical parameters (namely probing pocket depth and clinical attachment level) following administration of taurine also reflects the same."

 

[Lin]

I have receding gums. Wondering if they would benefit from a mouthwash of taurine powder diluted in water... or maybe even put the taurine solution in the waterpik...

 

[seano]

I have receding gums. Wondering if they would benefit from a mouthwash of taurine powder diluted in water... or maybe even put the taurine solution in the waterpik...

Did you try this?

 

[LeeLemonoil]

https://www.ncbi.nlm.nih.gov/m/pubmed/27412859/?i=11&from=taurine skin