Coconut Oil makes wounds in rats heal faster



Effect of topical application of virgin coconut oil on skin components and antioxidant status during dermal wound healing in young rats.
Nevin KG, Rajamohan T.

Department of Biochemistry, University of Kerala, Thiruvananthapuram, India.


The present study was undertaken to evaluate the effect of a topical application of virgin coconut oil (VCO) on excision wounds in young rats.
Three sets of experiments with 3 groups of female Sprague-Dawley rats each consisting of 6 animals were used for studying wound closure time, antioxidant status and biochemical parameters. Group 1 was the control; groups 2 and 3 were treated with 0.5 and 1.0 ml VCO, respectively, 24 h after wound creation for 10 days. After the experimental period, the healing property of VCO was evaluated by monitoring the time taken for complete epithelization as well as levels of various parameters of the wound's granulation tissue. The collagen solubility pattern, glycohydrolase activity, and histopathology of the granulation tissue were also analyzed. The antioxidant status during wound healing was monitored continuously for 14 days.
VCO-treated wounds healed much faster, as indicated by a decreased time of complete epithelization and higher levels of various skin components. Pepsin-soluble collagen showed a significant increase in VCO- treated wounds, indicating a higher collagen cross-linking. Glycohydrolase activities were also found to be increased due to a higher turnover of collagen. Antioxidant enzyme activities, and reduced glutathione and malondialdehyde levels were found to be increased on the 10th day after wounding, which were found to have returned to normal levels on day 14 in the treated wounds. The lipid peroxide levels were found to be lower in the treated wounds. A histopathological study showed an increase in fibroblast proliferation and neovascularization in VCO-treated wounds compared to controls.
The beneficial effect of VCO can be attributed to the cumulative effect of various biologically active minor components present in it.


Jan 27, 2013
I wonder if refined contains the same biologically active minor components.
Similar threads
Thread starter Title Forum Replies Date
2thecloudsabove Olive Oil, Not Coconut Oil, Makes Skin Ageing Slower Fats 40
Hgreen56 Ray said: "animals on coconut oil got lean". this study say the opposite? Coconut Oil 3
R Coconut Oil and Fructose Coconut Oil 2
M Does coconut oil kill bacteria or not? Ask For Help or Advice 32
Sam321 Asprin/Coconut Oil Enema Potential Solution For Fungus Digestion 9
Rinse & rePeat Removing Skin Growths With Coconut MCT Oil Skin 73
SuperStressed Vegetaline - claims to be 100% saturated fat hydrogenated coconut oil Coconut Oil 3
Hans Coconut oil for lowering blood sugar, insulin requirements, inflammation and appetite Scientific Studies 24
M Good Coconut Oil in Germany Diet 6
F Coconut Oil & Xylitol Toothpaste Recipe? Oral Health 24
S Coconut Oil Reduces DHT Orally? Coconut Oil 10
R J Deep Frying With Hydrogenated Coconut Oil? Coconut Oil 18
S My Experience With Coconut Oil Ask For Help or Advice 6
pauljacob Confusing Info From RP About Coconut Oil And Butter Diet 15
orewashin Why Does Coconut Oil/MCT Oil Burn My Throat? Coconut Oil 1
B Fractionated Coconut Oil As Sunscreen? Coconut Oil 1
L Can Micronized DHEA Dissolve In Coconut Oil? Digestion 3
Cecil Roids Coconut Oil Goes Rancid On My Skin, Any Ideas Why? Ask For Help or Advice 8
Velve921 Unrefined Coconut Oil Made Me Burn Coconut Oil 9
J Coconut Oil Ask For Help or Advice 6
Hgreen56 Coconut Oil + Starch = Weight Gain Or Weight Loss? Coconut Oil 6
J Coconut Oil And Mold Ask For Help or Advice 11
L This Coq10 Supplement I Found In The Mainstream Supermarket Has Coconut Oil In It Supplements, Pharmaceutical Drugs 1
milkboi Hydrogenated Coconut Oil German/European Source Coconut Oil 80
L Can Refined/hydrogenated Coconut Oil Cause Diarrhea? Coconut Oil 8
Z Coconut Oil Dog Weight Gain? Animals 3
S Study Claims That Coconut Oil Increase Oxidative Stress Compared To Sesame Oil (High PUFA) Diet 7
C How To Consume Coconut Oil By Itself Without Tasting Or Touching It Ask For Help or Advice 18
L Are Mashed Potatoes Okay With Coconut Oil Recipes 6
K What's The Deal With Liquid Coconut Oil? Coconut Oil 10
Locutus High Quality Tortilla Chips Fried In Coconut Oil Ask For Help or Advice 5
Momado965 Distillation Of Caprylic Acid/ Capric Acid Of Coconut Oil Supplements, Pharmaceutical Drugs 0
LiveWire Coconut Oil Irritating My Throat. Concern? Coconut Oil 2
K How To Make My Own Coconut Oil Based Lotion Body Care 0
L Ray's Carrot Salad - Coconut Oil Vs EVOO Carrot Salad, Bamboo Shoots, Mushrooms 0
L Hydrogenated Coconut Oil In A Plastic Container? Coconut Oil 11
J Coconut Oil And Kids Coconut Oil 1
C Who Experienced Benefits With Coconut Oil? Diet 16
michael94 2 Alternative To Coconut Oil Diet 3
H Coconut Oil Disturbing Digestion? Coconut Oil 6
T Olive Oil/coconut Oil With Lemon Empty Stomach Digestion 16
T What Is The Best Method For Combining Coconut Oil And Activated Charcoal? Ask For Help or Advice 23
jzeno Looking For Suggestions To Soften, Liquify Coconut Oil Quickly During Winter Months Miscellaneous 5
jzeno Tillamook Cheese, OJ, Coffee, Aspirin, Coconut Oil Are The Foods That Shot My Body Temperature Up Testimonials 10
Centsmom Coconut Oil/ Store Bought Eggs Ask For Help or Advice 8
Kartoffel Coconut Oil As Effective As Chlorhexidine For Plaque Reduction Oral Health 12
jzeno Here Me Out: Coconut Oil French Fries Coconut Oil 26
L Use Of Coconut Oil As Enema Saves Woman’s Colon From Being Surgically Removed Due To Colitis Coconut Oil 37
bzmazu COCONUT OIL KILLS Coconut Oil 16
whit To Arms! Mama Llama Cereal Controversy. Malt-o-Meal Replaces Coconut Oil With PUFA Canola Coconut Oil 11

Similar threads