PAIN - Unusual Causes & Unusual Remedies

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“Bee pollen has been used traditionally to reduce inflammation and swelling.

An animal study showed that bee pollen extract reduced swelling of rats’ paws by 75% (15Trusted Source).

In fact, its anti-inflammatory effects have been compared to several nonsteroidal anti-inflammatory drugs, such as phenylbutazone, indomethacin, analgin and naproxen (7Trusted Source).

Bee pollen packs several compounds that can reduce inflammation and swelling, including the antioxidant quercetin, which lowers the production of inflammatory omega-6 fatty acids, such as arachidonic acid (16Trusted Source).

What’s more, plant compounds in bee pollen may suppress biological processes that stimulate the production of inflammatory hormones such as tumor necrosis factor (TNF) (17Trusted Source).“

 
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“Stellaria plants have long been prescribed in homeopathic and traditional systems of medicine for managing painful symptoms tied to rheumatism, arthritis, PMS, digestive and respiratory issues, and more. plants have long been prescribed in homeopathic and traditional systems of medicine for managing painful symptoms tied to rheumatism, arthritis, PMS, digestive and respiratory issues, and more.”

 
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Peroxide is naturally present in raw honey.
Hydrogen peroxide is an antibacterial substance that is sold in pharmacies. It is made naturally in honey by an enzyme called glucose oxidase, which is added to the plant nectar by bees.

Glucose oxidase is not active in full strength honey because of the honey’s high acidity. However, when the honey is diluted (for example by the release of body fluids from a wound) the honey becomes less acid, the enzyme becomes active, and hydrogen peroxide is produced.

Honey contains plant-derived factors
Some honeys have antibacterial action that appears to be caused by phytochemicals that are found naturally in the nectar that the bees collect. For example, honey made from the flowers of New Zealand’s mānuka trees seems to be particularly powerful at killing bacteria.

Methylglyoxal is thought to be the major contributor to mānuka honey’s non-peroxide antibacterial activity. The antibacterial activity of mānuka honey is graded and given a 'UMF" number — the Unique Mānuka Factor. You can look at some of the early research that contributed to this identification of the UMF compund in Hunting for honey's healing power.”

 
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“Hydrogen peroxide can kill bacteria on contact and has been widely used for that purpose. However, straight hydrogen peroxide is unstable and rapidly loses its effectiveness when exposed to air or light. Hydrogen peroxide in high concentrations can also damage skin tissue. Therefore, the use fo pure hydrogen peroxide has lost its popularity among doctors and other medical professionals.

What most people don’t know is that honey has the necessary components to produce small amounts of hydrogen peroxide in a slow-release manner. This makes honey an ideal substance to use in the treatment of infected wounds and other bacterial disorders. The slow-release mechanism in honey that produces hydrogen peroxide is a chemical reaction. Honey contains glucose and an enzyme added by honeybees called glucose oxidase. Under the right conditions, glucose oxidase has the ability to break down glucose into hydrogen peroxide

Honey itself does not have the right conditions for this reaction to oocur. To become active and begin breaking down the glucose in honey, the glucose oxidase requires a pH of 5.5 to 8.0. The pH of undiluted honey is between 3.2 and 4.5 which is far too low to activate the enzyme. Another condition is also required before the glucose oxidase becomes active. For the enzyme to break glucose down into hydrogen peroxide, a certain amount of sodium must be present..

Honey alone does not contain enough sodium to make this happen. However, skin and body fluids have relatively high pH and sodium levels. When honey comes in contact with skin or an open wound, the high pH and sodium levels activate the glucose oxidase and it begins to break down the glucose, releasing hydrogen peroxide.“

 
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“Many people have noticed that pregnenolone has a "face-lifting" action. This effect seems to be produced by improved circulation to the skin, and by an actual contraction of some muscle-like cells in the skin. A similar effect can improve joint mobility in arthritis, tissue elasticity in the lungs, and even eyesight. Many studies have shown it to be protective of "fibrous tissues" in general, and in this connection it was proven to prevent the tumors that can be caused by estrogen.

Pregnenolone is largely converted into two other "youth-associated" protective hormones, progesterone and DHEA. At the age of 30, both men and women produce roughly 30 to 50 mg. of pregnenolone daily. When taken orally, even in the powdered form, it is absorbed fairly well. One dose of approximately 300 mg (the size of an aspirin tablet) keeps acting for about a week, as absorption continues along the intestine, and as it is "recycled" in the body. Part of this long lasting effect is because it improves the body's ability to produce its own pregnenolone. It tends to improve function of the thyroid and other glands, and this "normalizing" effect on the other glands helps to account for its wide range of beneficial effects.” -Ray Peat
 
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“Researchers from Denmark and France found in the paper Proceedings of the National Academy of Sciences that prolonged use of the commonly consumed painkiller could have some nasty side effects.

Net Doctor reported: “The small study, made up of just 31 male participants aged 18 to 35 years old, showed that taking ibuprofen increased the risk of compensated hypogonadism – a hormone imbalance whereby an individual has higher levels of luteinizing hormone (LH) than testosterone.

“For the research, participants were split into two groups. one group received 600mg or ibuprofen twice a day two weeks before and 30 days after an exercise session while the other acted as a control group. For the ibuprofen group, blood tests showed an 18% decrease in testosterone after 14 days, rising to a 23% decrease after 44 days.”

What is particularly alarming about the study is the participants were consuming around a third of what is considered a safe daily dose.”

 
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“Walking barefoot on grass and dirt stimulates almost an immediate catharsis to reduce overall pain levels by reducing inflammation and thereby allowing oxygenated blood to flow more freely and efficiently throughout the body.”

 
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“In addition to causing poor posture, wearing shoes also reduces the flexibility and strength of our feet. Each of these undesirable effects can lead to issues such as neck pain, back pain, and knee pain. By walking barefoot every day, you can retrain your feet to move naturally. Thus, you can correct the tone, balance, and function of the legs, pelvis, and lumbar spine.

The improvement of posture from grounding helps to prevent aches and pains in the human body. This is truly one of the best earthing advantages out there!“

 
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“Like its effects on chronic pain, grounding is encouraged for patients who suffer from knee and hip pain. Poor alignment in the feet can cause a ripple effect into the legs, knees, hips, and even lower back. As evidenced in this study, the natural movement from barefoot walking increases the blood flow to these areas, which can reduce inflammation around the nerves.”
 
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“As you’ve likely experienced firsthand, wearing shoes can lead to issues such as calluses and ingrown toenails. This is often due to the size, shape, and material of the shoe. Tight-fit shoes, in particular, can create friction that aggravates the skin around the feet.

By wearing no shoes (or barefoot/minimalist shoes), you can prevent calluses, ingrown toenails, bunions, and hammertoes from forming. You can also reverse many of these foot conditions through barefoot walking. This enhanced mobility increases blood flow, which promotes healing. Therefore, walking on the ground ensures that our feet stay in a healthy condition.”
 
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“Experienced barefoot runners are known to have strong feet that protects them from impact-related wounds and injuries. Alternatively, shoes with lots of support do not promote foot strength and functionality.

Dr. Daniel Lieberman, a researcher and professor at Harvard, suggests that “the energy that gets shot up your leg is about three times bigger in a cushioned shoe than if you’re barefoot.” This implies that while cushioned shoes may be comfortable, the force of impact remains high. As a result, this puts significant pressure on the joints.

Given that walking barefoot provides optimal strength and functionality of the feet, it could help to protect joints and even prevent issues like arthritis.”

 
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“Earth grounding techniques lead to all kinds of beneficial health outcomes. And perhaps no benefit of earthing is more profound than the one on the body’s inflammatory response.”


“In another study by the Journal of Alternative and Complementary Medicine, grounding was shown to reduce inflammation and blood markers, resulting in quicker healing for the groups tested.”
 
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“Many of the events involved in inflammation are increased by estrogen, and decreased by vitamin E.” -Ray Peat
 
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“ Excess clotting is known to be caused by too much estrogen, and also by a vitamin E deficiency.

Clotting leads to fibrosis, and there is clear evidence that vitamin E prevents and cures fibrotic diseases, but this still isn't generally accepted by the powerful medical institutions. Estrogen and polyunsaturated fats increase fibrosis.” -Ray Peat
 
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“In this study, aqueous extracts of peels of best known citrus fruits namely grapefruit (Citrus paradisi), lemon (C. limon), lime (C. aurantifolia) and orange (C. sinensis) were used. Depending on polyphenols content, the extracts were graded as orange > lemon > lime > grapefruit. Effects of the extracts on the release of histamine from rat peritoneal exudate cells (PECs) was measured to know anti-allergic activity. All extracts inhibited the release of histamine from rat PECs induced by the calcium ionophore A23187. Heating of the extracts at 100 °C for 10 min enhanced inhibition of histamine release. Effect of the oral administration of aqueous extract of grapefruit peel on the effusion of Chicago sky blue dye into the intraperitoneal cavity of mice was measured to know the anti-inflammatory activity. The extract potentially suppressed inflammation in the mice cavity as like indometacin, an anti-inflammatory drug. Therefore, the extracts of citrus peels are useful for developing anti-allergic and anti-inflammatory foods and supplements.“

 
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“Sadly, neither of these health foods lives entirely up to the hype. Spinach is loaded with iron and even contains a decent amount of protein, but it’s high in oxalates. Almonds are packed with fiber, protein, healthy fat, vitamin E, manganese, and magnesium, but like spinach, they’re high in oxalates.

In this post, we dig into the potential health issues related to oxalates and explain how to reduce your oxalate load.

Recognizing the Symptoms of High Oxalates

If you research oxalates, you’ll find many articles associating oxalic acid with kidney stones, but oxalic acid crystals can form in tissues and joints throughout the body and cause a wide range of health issues, including the following:

  • Arthritis
  • Gout
  • Inflammation
  • Inflammatory bowel disease (IBD)
  • Joint pain
  • Kidney stones
  • Mast cell activation syndrome (MCAS), which causes allergic-like reactions
  • Muscle pain
  • Painful urination
  • Rashes
  • Urinary tract infections (UTIs)
Ironically, people often encounter problems with oxalates when they’re trying to be healthy. We frequently see patients who try elimination diets, such as a dairy-free or a gluten-free diet. Some overshoot the mark with spinach, kale, and almonds. In their smoothie for instance, they might be adding kale and almond milk daily, in addition to consuming almond butter, almond flour, and lots of salad. The best approach is a moderate one. Don’t overdo a food type on your way to wellness.

Reducing Consumption of High-Oxalate Foods

One of the keys to preventing oxalates from becoming a health problem is to limit your consumption of foods high in oxalates. Here are some foods that are highest in oxalates:

  • Beans: Navy beans and black beans are the worst, and other beans may also be relatively high in oxalates
  • Berries: Raspberries top the list, and blueberries, black berries, and gooseberries are relatively high in oxalates
  • Beverages: Black tea, chocolate drinks (like hot cocoa), soy milk, and nut milks (such as almond milk)
  • Fruits: Figs, kiwi, dates, and currants
  • Grains: Amaranth, buckwheat, bran, and high-fiber cereals
  • Nuts and seeds: Almonds, peanuts, sesame seeds, and all nut butters
  • Soy products: Soy milk, tofu, and other foods made from soybeans
  • Vegetables: Leafy greens (spinach, kale, chard, beet greens, and dandelion greens), rhubarb, okra, and baked potatoes (with the skin)“

 
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“More specifically, hydrogen peroxide has been shown to form in honey by the action of the enzyme glucose oxidase that produces gluconic acid and hydrogen peroxide from glucose. Flavonoids have been shown to have antibacterial properties (Mundo et al., 2004), and high sugar concentrations produce a hypertonic condition causing plasmolysis of microbial cells resulting in growth inhibition and death (Cai and Wu, 1996).
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5. Conclusions​

Within the limitations of the study it can be concluded that topical application of honey can modify the pH, reduce bacterial counts, and inhibit bacterial growth. These data suggested that topical application/chewing of honey might help prevent gingivitis and caries in patients undergoing orthodontic treatment. Further studies will be required to substantiate these preliminary observations.“

 
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