Looking For Advice Regarding Methotrexate And Ototoxicity

[MistyH]

My 35 year old daughter was treated with methotrexate for an ectopic pregnancy about 3 months ago. She is now suffering from tinnitus and an audiologist said she shows hearing loss. This all came on post treatment so she and I are convinced this is truly a side effect of the drug as noted in side effects to look for. The audiologist is arguing time frame.

Supplements mentioned that she's considering include melatonin, zinc, manganese and B, with emphasis on B12.

We're working on her estrogen because she is clearly ED with several other symptoms. Varicose veins, obesity, Plantar Fascitis, a TSH of 11 previously with no treatment (working on that now without Physician's help, daughter has Kaiser and is quite passive)

Any help and advice is very much appreciated.

 

[Let Go]

Do you have a copy of her Audiogram?

 

[Let Go]

Possibly Otosclerosis? Fairly common after pregnancy. If she has a low frequency loss or a conductive loss that's more than likely the case. If she has a high frequency sensorineural loss than possibly the
methotrexate.
She could have already had a mild sensorineural loss and the stress of the situation has made it worse

 

[MistyH]

Just asked for it. Thank you for your reply.

 

[Let Go]

No problem, if you can post a copy or PM me I can at least tell you what type of loss and maybe where to start.
Has she seen an ENT or an Otolaryngologist or just an Audiologist?

 

[MistyH]

No problem, if you can post a copy or PM me I can at least tell you what type of loss and maybe where to start.
Has she seen an ENT or an Otolaryngologist or just an Audiologist?

I believe just an audiologist at this point. She just e-mailed Kaiser for her records.

 

[Trix]

My 35 year old daughter was treated with methotrexate for an ectopic pregnancy about 3 months ago. She is now suffering from tinnitus and an audiologist said she shows hearing loss. This all came on post treatment so she and I are convinced this is truly a side effect of the drug as noted in side effects to look for. The audiologist is arguing time frame.

Supplements mentioned that she's considering include melatonin, zinc, manganese and B, with emphasis on B12.

We're working on her estrogen because she is clearly ED with several other symptoms. Varicose veins, obesity, Plantar Fascitis, a TSH of 11 previously with no treatment (working on that now without Physician's help, daughter has Kaiser and is quite passive)

Any help and advice is very much appreciated.

Methotrexate depletes Folate, but I would also look into B1 (allithiamine), which I've read helps with hearing loss by increasing oxygen to the ear area. Consider B2 (R-5-P) and B6 (P-5-P). If you get a B Complex supplement, get one that have the activated vitamins, that goes for B12 too.

 

[MistyH]

Methotrexate depletes Folate, but I would also look into B1 (allithiamine), which I've read helps with hearing loss by increasing oxygen to the ear area. Consider B2 (R-5-P) and B6 (P-5-P). If you get a B Complex supplement, get one that have the activated vitamins, that goes for B12 too.

Thank you. I've had her taking desiccated liver for her B vitamins.

 

[MistyH]

No problem, if you can post a copy or PM me I can at least tell you what type of loss and maybe where to start.
Has she seen an ENT or an Otolaryngologist or just an Audiologist?

Thank you for your offer. I just sent you the report